{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T12:20:47Z","timestamp":1763036447954,"version":"build-2065373602"},"reference-count":65,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2009,12,1]],"date-time":"2009-12-01T00:00:00Z","timestamp":1259625600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Periodontology"],"published-print":{"date-parts":[[2009,12]]},"abstract":"<jats:p><jats:bold>Background:<\/jats:bold> The gingival cyst of the adult (GCA) is an uncommon developmental cyst of odontogenic origin most frequently seen near mandibular canines and premolars and is routinely treated with excisional biopsy. This article presents a case of a GCA treated with a combined regenerative approach and reviews the GCA literature with an emphasis on the clinical aspects of this lesion.<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold> A 54 year\u2010old man presented for treatment of generalized severe chronic periodontitis. Clinical examination revealed a cystic lesion in the gingiva of the mandibular canine\u2010premolar area. Radiographs revealed a well\u2010defined radiolucency in the coronal one\u2010third of the tooth roots. Surgical enucleation of the lesion revealed root exposure of the second premolar. Because of the anatomy of the lesion\u2010associated defect, regenerative treatment, using a combination of freeze\u2010dried bone allograft and a collagen membrane, was considered the therapeutic approach of choice.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> The biopsy revealed histologic features consistent with a GCA. Clinical and radiographic examinations 1 year post\u2010surgery indicated uneventful soft tissue healing and bone fill of the initial defect. The review of the literature revealed only one other case of root exposure associated with GCA and no previous report of regenerative therapy.<\/jats:p><jats:p><jats:bold>Conclusions:<\/jats:bold> In rare instances, a GCA lesion may result in tooth\u2010root exposure. In such cases, a combined regenerative treatment approach may be used to achieve resolution.<\/jats:p>","DOI":"10.1902\/jop.2009.090311","type":"journal-article","created":{"date-parts":[[2009,12,7]],"date-time":"2009-12-07T08:57:14Z","timestamp":1260176234000},"page":"2073-2081","source":"Crossref","is-referenced-by-count":11,"title":["Gingival Cyst of the Adult: Regenerative Therapy of Associated Root Exposure. A Case Report and Literature Review"],"prefix":"10.1002","volume":"80","author":[{"given":"W. 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