{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T16:17:40Z","timestamp":1779293860566,"version":"3.51.4"},"reference-count":30,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2010,4,1]],"date-time":"2010-04-01T00:00:00Z","timestamp":1270080000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Periodontology"],"published-print":{"date-parts":[[2010,4]]},"abstract":"<jats:p><jats:bold>Background:<\/jats:bold> A 47\u2010year\u2010old male non\u2010smoker with a history of psoriasis sought a consultation because of a painless, hard\u2010on\u2010palpation, 1\u2010cm exophytic lesion with a smooth and speckled surface located on the hard palate adjacent to tooth #12. The radiologic examination revealed no bone destruction. The lesion was clinically diagnosed as a fibrous hyperplasia or chronic pyogenic granuloma.<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold> The lesion was surgically removed, fixed in 10% neutral buffered formalin for 24 hours, and, following common practice, embedded in paraffin. Sections, 4 \u03bcm thick, were stained with hematoxylin and eosin, periodic acid\u2010Schiff, and alcian blue, pH 2.5. An immunohistochemical study was also performed.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> A definitive diagnosis of a mucinous adenocarcinoma (MAC), a very rare, high\u2010grade malignancy tumor that more frequently appears in the elderly, was made. With the definitive diagnosis of an MAC of the palate, the upper\u2010left premolars were extracted using a box osteotomy, and the surgical wound was reconstructed with a Bichat fat\u2010pad flap. After a 6\u2010month follow\u2010up, no recurrence or cervical metastases were identified.<\/jats:p><jats:p><jats:bold>Conclusions:<\/jats:bold> An MAC of a minor salivary gland may arise as a gingival exophytic lesion with a clinical appearance similar to a pyogenic granuloma. The existence of a light speckled pattern on the surface of the lesion indicates that an incisional biopsy is needed before surgical treatment to make possible a definitive diagnosis. To avoid delays in diagnosis and erroneous clinical approaches to exophytic gingival lesions, periodontists and practitioners should routinely perform a pathologic analysis to confirm the diagnosis when dealing with these kinds of lesions.<\/jats:p>","DOI":"10.1902\/jop.2009.090370","type":"journal-article","created":{"date-parts":[[2010,4,6]],"date-time":"2010-04-06T20:19:54Z","timestamp":1270585194000},"page":"626-631","source":"Crossref","is-referenced-by-count":10,"title":["Gingival Mucinous Adenocarcinoma of a Minor Salivary Gland"],"prefix":"10.1002","volume":"81","author":[{"given":"Juan","family":"Seoane","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pablo","family":"Varela\u2010Centelles","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Javier","family":"L\u00f3pez\u2010Ni\u00f1o","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"In\u00e9s","family":"V\u00e1zquez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ihab","family":"Abdulkader","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tom\u00e1s","family":"Garc\u00eda\u2010Caballero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2010,4]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"E414","article-title":"A retrospective analysis of gingival biopsied lesions in South Indian population: 2001\u20102006","volume":"13","author":"Shamim T","year":"2008","journal-title":"Med Oral Patol Oral Cir Bucal"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2006.050408"},{"key":"e_1_2_6_4_1","first-page":"97","article-title":"Squamous cell carcinoma of the gingiva presenting as localized periodontal disease","volume":"38","author":"Yoon TY","year":"2007","journal-title":"Quintessence Int"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-051X.2003.00391.x"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1994.tb01173.x"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/bdj.2007.994"},{"key":"e_1_2_6_8_1","first-page":"E489","article-title":"Primary oral squamous cell carcinoma arising around dental osseointegrated implants mimicking peri\u2010implantitis","volume":"13","author":"Eguia del Valle A","year":"2008","journal-title":"Med Oral Patol Oral Cir Bucal"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.10004"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1991.62.9.573"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1368-8375(01)00077-X"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/0964-1955(95)00031-3"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/0278-2391(89)90385-6"},{"key":"e_1_2_6_14_1","first-page":"362","volume-title":"Soft tissue tumors","author":"Neville BW","year":"1995"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0714.1993.tb00128.x"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2009.01407.x"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00428-008-0699-1"},{"key":"e_1_2_6_18_1","first-page":"234","volume-title":"Pathology & Genetics Head and Neck Tumors. 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