{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T03:30:01Z","timestamp":1787023801461,"version":"build-2736575974"},"reference-count":31,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2010,4,1]],"date-time":"2010-04-01T00:00:00Z","timestamp":1270080000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Periodontology"],"published-print":{"date-parts":[[2010,4]]},"abstract":"<jats:p>\n                    <jats:bold>Background:<\/jats:bold>\n                    One of the most common esthetic concerns associated with periodontal tissues is gingival recession. There are multiple periodontal plastic surgery approaches documented in the literature for the treatment of such defects. With the tremendous advances being made in periodontal science and technology, tissue engineering could be considered among the latest exciting techniques for recession management.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Methods:<\/jats:bold>\n                    In this split\u2010mouth, controlled, double\u2010masked clinical case series, 20 sites from 10 patients with Miller Class I or II recessions affecting canines or premolars in the maxillary arch were selected. One tooth in each patient was randomized to receive either a subepithelial connective tissue graft (SCTG) (control group) or an acellular dermal matrix allograft (ADMA) seeded with autologous gingival fibroblasts (test group) under a coronally positioned flap. Clinical parameters, including recession depth, probing depth, clinical attachment level, width of keratinized tissue, attached gingiva, and plaque scores, were recorded by a calibrated examiner at baseline and 3 and 6 months. The inflammation of grafted sites was scored, and the healing time was calculated. The final esthetic outcome of treated sites was assessed by the root coverage esthetic score at the end of 6 months.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results:<\/jats:bold>\n                    There were no significant differences between test and control sites for all measured clinical parameters. However, the test sites demonstrated less inflammation in the early postoperative period.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusion:<\/jats:bold>\n                    Within the limits of this case series, the results indicate that an ADMA seeded with autologous gingival fibroblasts by tissue\u2010engineering technology may be explored as a substitute to an SCTG for the treatment of Miller Class I and II recession defects.\n                  <\/jats:p>","DOI":"10.1902\/jop.2009.090530","type":"journal-article","created":{"date-parts":[[2010,4,6]],"date-time":"2010-04-06T20:19:54Z","timestamp":1270585194000},"page":"616-625","source":"Crossref","is-referenced-by-count":56,"title":["Acellular Dermal Matrix Seeded With Autologous Gingival Fibroblasts for the Treatment of Gingival Recession: A Proof\u2010of\u2010Concept Study"],"prefix":"10.1002","volume":"81","author":[{"given":"Hiral M.","family":"Jhaveri","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahesh S.","family":"Chavan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geetanjali B.","family":"Tomar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vijay L.","family":"Deshmukh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohan R.","family":"Wani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr.","given":"Preston D.","family":"Miller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2010,4]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1956.27.2.92"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1968.39.2.65"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1975.tb01721.x"},{"key":"e_1_2_7_5_1","first-page":"152","article-title":"Free autogenous gingival grafts. III. Utilization of grafts in the treatment of gingival recession","volume":"6","author":"Sullivan HC","year":"1968","journal-title":"Periodontics"},{"key":"e_1_2_7_6_1","first-page":"51","article-title":"A comparative study of root coverage obtained with an acellular dermal matrix versus a connective tissue graft: Results of 107 recession defects in 50 consecutively treated patients","volume":"20","author":"Harris RJ","year":"2000","journal-title":"Int J Periodontics Restorative Dent"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1985.56.12.715"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1985.56.7.397"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1992.63.5.477"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-051X.29.s3.11.x"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1006\/jsre.1996.0210"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.burns.2003.12.007"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2007.060060"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2003.74.2.262"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0142-9612(01)00270-8"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2005.76.6.867"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2005.76.6.881"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2007.070083"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2008.080017"},{"issue":"2","key":"e_1_2_7_20_1","first-page":"8","article-title":"A classification of marginal tissue recession","volume":"5","author":"Miller PD","year":"1985","journal-title":"Int J Periodontics Restorative Dent"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016356408993968"},{"key":"e_1_2_7_22_1","first-page":"3","article-title":"A modified gingival index for use in clinical trials","volume":"8","author":"Lobene RR","year":"1986","journal-title":"Clin Prev Dent"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2009.080565"},{"key":"e_1_2_7_24_1","first-page":"279","article-title":"A single incision technique to harvest subepithelial connective tissue grafts from the palate","volume":"19","author":"H\u00fcrzeler MB","year":"1999","journal-title":"Int J Periodontics Restorative Dent"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1996.tb00608.x"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2001.72.11.1477"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2004.75.5.734"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2005.76.8.1323"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2000.71.8.1297"},{"key":"e_1_2_7_30_1","first-page":"63","article-title":"Bilaminar technique in the treatment of a deep cervical abrasion defect","volume":"28","author":"Mele M","year":"2008","journal-title":"Int J Periodontics Restorative Dent"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2005.00660.x"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2005.76.2.178"}],"container-title":["Journal of Periodontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/pdf\/10.1902\/jop.2009.090530","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T11:55:36Z","timestamp":1760874936000},"score":1,"resource":{"primary":{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/10.1902\/jop.2009.090530"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,4]]},"references-count":31,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2010,4]]}},"alternative-id":["10.1902\/jop.2009.090530"],"URL":"https:\/\/doi.org\/10.1902\/jop.2009.090530","archive":["Portico"],"relation":{},"ISSN":["0022-3492","1943-3670"],"issn-type":[{"value":"0022-3492","type":"print"},{"value":"1943-3670","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,4]]}}}