{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T07:27:47Z","timestamp":1790321267455,"version":"4.1.0"},"reference-count":28,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2010,8,1]],"date-time":"2010-08-01T00:00:00Z","timestamp":1280620800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Periodontology"],"published-print":{"date-parts":[[2010,8]]},"abstract":"<jats:p>\n                    <jats:bold>Background:<\/jats:bold>\n                    For root coverage therapy, the connective tissue graft (CTG) plus coronally advanced flap (CAF) is considered the gold standard therapy against which alternative therapies are generally compared. When evaluating these therapies, in addition to traditional measures of root coverage, subject\u2010reported, qualitative measures of esthetics, pain, and overall preferences for alternative procedures should also be considered. This study determines if a xenogeneic collagen matrix (CM) with CAF might be as effective as CTG+CAF in the treatment of recession defects.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Methods:<\/jats:bold>\n                    This study was a single\u2010masked, randomized, controlled, split\u2010mouth study of dehiscence\u2010type recession defects in contralateral sites; one defect received CTG+CAF and the other defect received CM+CAF. A total of 25 subjects (8 male, 17 female; mean age: 43.7 \u00b1 12.2 years) were evaluated at 6 months and 1 year. The primary efficacy endpoint was recession depth at 6 months. Secondary endpoints included traditional periodontal measures, such as width of keratinized tissue and percentage of root coverage. Subject\u2010reported values of pain, discomfort, and esthetic satisfaction were also recorded.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results:<\/jats:bold>\n                    At 6 months, recession depth was on average 0.52 mm for test sites and 0.10 mm for control sites. Recession depth change from baseline was statistically significant between test and control, with an average of 2.62 mm gained at test sites and 3.10 mm gained at control sites for a difference of 0.4 mm (\n                    <jats:italic>P<\/jats:italic>\n                    = 0.0062). At 1 year, test percentage of root coverage averaged 88.5%, and controls averaged 99.3% (\n                    <jats:italic>P<\/jats:italic>\n                    = 0.0313). Keratinized tissue width gains were equivalent for both therapies and averaged 1.34 mm for test sites and 1.26 mm for control sites (\n                    <jats:italic>P<\/jats:italic>\n                    = 0.9061). There were no statistically significant differences between subject\u2010reported values for esthetic satisfaction, and subjects' assessments of pain and discomfort were also equivalent.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusion:<\/jats:bold>\n                    When balanced with subject\u2010reported esthetic values and compared to historical root coverage outcomes reported by other investigators, CM+CAF presents a viable alternative to CTG+CAF, without the morbidity of soft tissue graft harvest.\n                  <\/jats:p>","DOI":"10.1902\/jop.2010.090698","type":"journal-article","created":{"date-parts":[[2010,3,29]],"date-time":"2010-03-29T12:39:13Z","timestamp":1269866353000},"page":"1108-1117","source":"Crossref","is-referenced-by-count":171,"title":["Xenogeneic Collagen Matrix With Coronally Advanced Flap Compared to Connective Tissue With Coronally Advanced Flap for the Treatment of Dehiscence\u2010Type Recession Defects"],"prefix":"10.1002","volume":"81","author":[{"given":"Michael K.","family":"McGuire","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E. Todd","family":"Scheyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2010,8]]},"reference":[{"issue":"2","key":"e_1_2_7_2_1","first-page":"CD007161","article-title":"Root coverage procedures for the treatment of localized recession\u2010type defects","author":"Chambrone L","year":"2009","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1902\/annals.2003.8.1.303"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2005.76.9.1588"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2008.070325"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2006.050296"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2004.75.3.413"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1998.69.2.138"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2003.74.8.1110"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2005.76.6.881"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2001.72.8.998"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2009.080502"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2008.01267.x"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2008.080017"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2009.090041"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-051X.29.s3.11.x"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1985.56.12.715"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1982.tb02105.x"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1977.48.8.456"},{"key":"e_1_2_7_20_1","first-page":"103","article-title":"Evaluation of a special collagen implant material as a substitute for free mucosal or skin grafts in oral soft tissue surgery","author":"Boyne PJ","year":"2002","journal-title":"Proc Am Institute Oral Biol"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2009.01460.x"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1972.43.10.623"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1981.tb02041.x"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1902\/annals.1996.1.1.671"},{"key":"e_1_2_7_25_1","first-page":"40","article-title":"Marginal tissue recession in general dental practice: A preliminary study","volume":"3","author":"Wilson R","year":"1983","journal-title":"Int J Periodontics Restorative Dent"},{"key":"e_1_2_7_26_1","first-page":"145","article-title":"Surgical therapy","volume":"9","author":"Periodontal Literature Reviews","year":"1996","journal-title":"J Periodontol"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1708-8240.1999.tb00414.x"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1902\/annals.2003.8.1.193"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2005.76.12.2205"}],"container-title":["Journal of Periodontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/pdf\/10.1902\/jop.2010.090698","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T13:34:47Z","timestamp":1760880887000},"score":1,"resource":{"primary":{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/10.1902\/jop.2010.090698"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,8]]},"references-count":28,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2010,8]]}},"alternative-id":["10.1902\/jop.2010.090698"],"URL":"https:\/\/doi.org\/10.1902\/jop.2010.090698","archive":["Portico"],"relation":{},"ISSN":["0022-3492","1943-3670"],"issn-type":[{"value":"0022-3492","type":"print"},{"value":"1943-3670","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,8]]}}}