{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T12:20:53Z","timestamp":1790770853684,"version":"4.1.0"},"reference-count":24,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2010,11,1]],"date-time":"2010-11-01T00:00:00Z","timestamp":1288569600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Periodontology"],"published-print":{"date-parts":[[2010,11]]},"abstract":"<jats:p><jats:bold>Background:<\/jats:bold> The present study considers the correlation between the meaning of keratinized mucosa (KM) and the long\u2010term maintenance of endosseous root\u2010form dental implants placed in fresh sockets and immediately loaded.<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold> Twenty\u2010nine patients requiring extractions of \u22652 teeth in the maxilla and mandible were selected. One\u2010hundred thirty\u2010two maxillary and 32 mandibular teeth, in the incisor, canine, and premolar regions, were extracted. Implants were positioned in fresh sockets and immediately loaded. Based on the amounts of KM, implants were categorized as follows: KM \u22652 mm (group A) and KM &lt;2 mm (group B). Clinical parameters (probing depth, modified plaque index, modified bleeding index, and gingival index) and marginal bone levels were followed at 4 years after implant placement. Comparisons between group A and B values were performed by the Student two\u2010tailed <jats:italic>t<\/jats:italic> test.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> At 4\u2010year follow\u2010up, a survival rate of 100% was reported for all implants. The mean values of group B were significantly higher (<jats:italic>P<\/jats:italic> &lt;0.05) than group A for the following parameters: gingival index (group A, 0.67 \u00b1 0.09; group B, 1.01 \u00b1 0.11); modified plaque index (group A, 1.18 \u00b1 0.09; group B, 1.71 \u00b1 0.12); and modified bleeding index (group A, 0.35 \u00b1 0.05; group B, 0.78 \u00b1 0.05). Gingival recession was significantly elevated in group B. In both group A and group B, up to 60% of gingival recession occurred within the first 6 months. For mean bone loss values, statistically non\u2010significant differences were reported between groups.<\/jats:p><jats:p><jats:bold>Conclusions:<\/jats:bold> At 4\u2010year follow\u2010up, the results suggested that the presence of mid\u2010buccal KM is not a critical factor in the maintenance of interproximal bone level around fresh socket implants immediately loaded. Conversely, less width of KM is significantly associated with more gingival inflammation, more plaque accumulation, and more gingival recession.<\/jats:p>","DOI":"10.1902\/jop.2010.100115","type":"journal-article","created":{"date-parts":[[2010,5,7]],"date-time":"2010-05-07T14:27:30Z","timestamp":1273242450000},"page":"1629-1634","source":"Crossref","is-referenced-by-count":65,"title":["A 4\u2010Year Evaluation of the Peri\u2010Implant Parameters of Immediately Loaded Implants Placed in Fresh Extraction Sockets"],"prefix":"10.1002","volume":"81","author":[{"given":"Roberto","family":"Crespi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Cappar\u00e8","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enrico","family":"Gherlone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2010,11]]},"reference":[{"key":"e_1_2_7_2_1","first-page":"439","article-title":"Immediate restoration of implants placed into fresh extraction sockets for single\u2010tooth replacement: A prospective clinical study","volume":"25","author":"Cornelini R","year":"2005","journal-title":"Int J Periodontics Restorative Dent"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2006.060072"},{"key":"e_1_2_7_4_1","first-page":"955","article-title":"Immediate occlusal loading of implants 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