{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T15:57:35Z","timestamp":1789660655277,"version":"4.0.1"},"reference-count":37,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Periodontology"],"published-print":{"date-parts":[[2011,1]]},"abstract":"<jats:p><jats:bold>Background:<\/jats:bold> The goal of this study is to evaluate the degree of staining and clinical efficacy of a chlorhexidine mouthwash with an antidiscoloration system (ADS) versus 0.2% chlorhexidine mouthwash (traditional). Secondary objectives are to evaluate the patient \u201ccompliance\u201d factor according to patterns assigned by the clinician and to observe the side effects of the two mouthwashes.<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold> This comparative study is carried out on a sample of 15 non\u2010smoking patients with chronic periodontitis at the Department of Periodontology, the International University of Catalunya, Barcelona, Spain. All patients used either 0.2% chlorhexidine mouthwash (control group = bottle B) or chlorhexidine with ADS (test group = bottle A) for 15 days. Each patient first rinsed with a randomly assigned mouthwash for 15 days followed by a 15\u2010day washout period. Subsequently, each patient used a second mouthwash. Before each cycle, a full dental prophylaxis was performed. The plaque, gingival, and Brecx staining indexes were used.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> The results showed less tooth staining with the test group (<jats:italic>P<\/jats:italic> &lt;0.01). No statistically significant differences were observed in plaque (<jats:italic>P<\/jats:italic> = 0.1496) and gingival indexes (<jats:italic>P<\/jats:italic> = 0.1688). Eighty\u2010eight percent of patients followed the instructions outlined in the protocol. In terms of other adverse effects, two patients reported a bad taste with both mouthwashes.<\/jats:p><jats:p><jats:bold>Conclusions:<\/jats:bold> The test group with ADS had less staining than the control group during a usage period of 15 days. However, the two mouthwashes seemed to be equally effective as antiplaque and antigingivitis agents.<\/jats:p>","DOI":"10.1902\/jop.2010.100289","type":"journal-article","created":{"date-parts":[[2010,7,23]],"date-time":"2010-07-23T14:56:08Z","timestamp":1279896968000},"page":"80-85","source":"Crossref","is-referenced-by-count":27,"title":["0.2% Chlorhexidine Mouthwash With an Antidiscoloration System Versus 0.2% Chlorhexidine Mouthwash: A Prospective Clinical Comparative Study"],"prefix":"10.1002","volume":"82","author":[{"given":"Carols","family":"Sol\u00eds","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Santos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9","family":"Nart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deborah","family":"Violant","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,1]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0757.1997.tb00199.x"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1987.tb00968.x"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2004.00563.x"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1989.tb01661.x"},{"key":"e_1_2_7_6_1","first-page":"78","article-title":"The status, future, and problems of oral antiseptics","volume":"3","author":"Bouwsma OJ","year":"1996","journal-title":"Curr Opin Periodontol"},{"key":"e_1_2_7_7_1","first-page":"15","article-title":"Chemotherapeutic agents in the prevention and treatment of periodontal disease","volume":"64","author":"Wolff LF","year":"1985","journal-title":"Northwest Dent"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0757.2004.03671.x"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0757.1997.tb00104.x"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0757.1995.tb00046.x"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1159\/000261043"},{"key":"e_1_2_7_12_1","first-page":"31","article-title":"Effects of an oral rinse on experimental gingivitis plaque formation, and formed plaque","volume":"4","author":"Lusk SS","year":"1974","journal-title":"J Am Soc Prev Dent"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1993.tb00780.x"},{"key":"e_1_2_7_14_1","first-page":"46","article-title":"The clinical effect of dentifrices containing stabilized stannous fluoride on plaque formation and gingivitis \u2014 A six\u2010month study with ad libitum brushing","volume":"6","author":"Beiswanger BB","year":"1995","journal-title":"J Clin Dent"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1986.tb01434.x"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.1989.0011"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1985.tb01364.x"},{"key":"e_1_2_7_18_1","first-page":"15","article-title":"Hydrogen peroxide, the effect on plaque and gingivitis when used in an oral irrigator","volume":"12","author":"Jones CM","year":"1990","journal-title":"Clin Prev Dent"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0757.1997.tb00106.x"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-5037.2005.00117.x"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0765.1986.tb01512.x"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0757.1997.tb00105.x"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1994.65.10.904"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1982.tb02098.x"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2006.00917.x"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1994.tb00313.x"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-051X.30.s5.5.x"},{"key":"e_1_2_7_28_1","first-page":"59","article-title":"Antiseptics and antibiotics as chemotherapeutic agents for periodontitis management","volume":"21","author":"Ciancio SG","year":"2000","journal-title":"Compend Contin Educ Dent"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1985.tb00924.x"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-5037.2004.00083.x"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1902\/annals.1999.4.1.1"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016356309011240"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016356408993968"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1967.38.6_part2.610"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1981.tb02029.x"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.1177\/00220345930720080601"},{"key":"e_1_2_7_37_1","first-page":"697","article-title":"The optimum characteristics of toothbrushes for personal oral hygiene","volume":"70","author":"Bass CC","year":"1948","journal-title":"Dent Items Interest"},{"key":"e_1_2_7_38_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2008.01238.x"}],"container-title":["Journal of Periodontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/pdf\/10.1902\/jop.2010.100289","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T13:01:26Z","timestamp":1760878886000},"score":1,"resource":{"primary":{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/10.1902\/jop.2010.100289"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,1]]},"references-count":37,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2011,1]]}},"alternative-id":["10.1902\/jop.2010.100289"],"URL":"https:\/\/doi.org\/10.1902\/jop.2010.100289","archive":["Portico"],"relation":{},"ISSN":["0022-3492","1943-3670"],"issn-type":[{"value":"0022-3492","type":"print"},{"value":"1943-3670","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,1]]}}}