{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T00:28:45Z","timestamp":1760920125624,"version":"build-2065373602"},"reference-count":56,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2011,5,1]],"date-time":"2011-05-01T00:00:00Z","timestamp":1304208000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Periodontology"],"published-print":{"date-parts":[[2011,5]]},"abstract":"<jats:p><jats:bold>Background:<\/jats:bold> This study clinically evaluates the treatment outcome of coronally positioned flap (CPF) associated with anorganic bone mineral\/peptide\u201015 (ABM\/P\u201015) in terms of root coverage and gain in clinical attachment level (CAL) and bone height (BH) in isolated Class I gingival recession (GR) defects.<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold> Fifteen healthy subjects with bilateral and comparable Miller Class I GR defects were selected. The defects were randomly assigned either to the test group (CPF with ABM\/P\u201015) or to the control group (CPF only).<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> Six months after surgery, a reduction in GR was observed in the test and control groups (2.20 \u00b1 0.54 and 2.40 \u00b1 0.80 mm, respectively; <jats:italic>P<\/jats:italic> &lt;0.001) with no intergroup difference (<jats:italic>P<\/jats:italic> = 0.33). Complete root coverage was obtained in 10 and 11 defects in the test and control groups, respectively. In the test group 85.56% \u00b1 21.69% and in the control group 90.00% \u00b1 18.42% of the exposed root was covered. Although not clinically significant, a statistically greater increase in the gingival thickness was observed in the test group (0.03 mm; <jats:italic>P<\/jats:italic> = 0.01). CAL gain was significant in both groups (test group, 1.93 \u00b1 0.44 mm; control group, 2.13 \u00b1 1.15 mm; <jats:italic>P<\/jats:italic> &lt;0.001) with no intergroup difference (<jats:italic>P<\/jats:italic> = 0.42). Intergroup and intragroup differences in width of keratinized tissue and BH were not significant (<jats:italic>P<\/jats:italic> \u22650.16). In the test group, a positive correlation was observed between BH at baseline and the reduction in GR (<jats:italic>r<\/jats:italic> = 0.56; <jats:italic>P<\/jats:italic> = 0.03).<\/jats:p><jats:p><jats:bold>Conclusions:<\/jats:bold> In isolated Class I GR defects, CPF associated with ABM\/P\u201015 provided no significant difference in root coverage and CAL gain compared to CPF alone. In the ABM\/P\u201015 group, a greater reduction in GR was associated with higher bone level at baseline.<\/jats:p>","DOI":"10.1902\/jop.2010.100434","type":"journal-article","created":{"date-parts":[[2010,11,16]],"date-time":"2010-11-16T10:33:17Z","timestamp":1289903597000},"page":"700-707","source":"Crossref","is-referenced-by-count":17,"title":["Use of Anorganic Bovine\u2010Derived Hydroxyapatite Matrix\/Cell\u2010Binding Peptide (P\u201015) in the Treatment Isolated Class I Gingival Recession of Defects: A Pilot Study"],"prefix":"10.1002","volume":"82","author":[{"given":"Carlos A.","family":"Nazareth","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patricia R.","family":"Cury","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,5]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1902\/annals.1996.1.1.671"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1999.70.1.30"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2004.75.10.1377"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1998.tb02416.x"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1752-7325.1995.tb02335.x"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-051X.2002.290804.x"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1976.tb00040.x"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1997.68.8.779"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2003.74.8.1126"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2000.71.9.1441"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2002.73.1.53"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-4636(199608)31:4<545::AID-JBM15>3.0.CO;2-F"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2005.76.10.1690"},{"key":"e_1_2_7_15_1","first-page":"146","article-title":"Periodontal regeneration following use of ABM\/P\u20101 5: A case report","volume":"22","author":"Yukna R","year":"2002","journal-title":"Int J Periodontics Restorative Dent"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2000.71.11.1671"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1998.69.6.655"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2007.070234"},{"key":"e_1_2_7_19_1","first-page":"8","article-title":"A classification of marginal tissue recession","volume":"5","author":"Miller PD","year":"1985","journal-title":"Int J Periodontics Restorative Dent"},{"key":"e_1_2_7_20_1","first-page":"229","article-title":"Problems and proposals for recording gingivitis and plaque","volume":"25","author":"Ainamo J","year":"1975","journal-title":"Int Dent J"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2006.050450"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2007.060428"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2003.74.1.3"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2005.00706.x"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1996.tb00624.x"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1996.67.1.7"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2001.72.10.1301"},{"key":"e_1_2_7_28_1","first-page":"444","article-title":"Guided tissue regeneration versus coronally repositioned flap in the treatment of recession with double papillae","volume":"18","author":"Matarasso S","year":"1998","journal-title":"Int J Periodontics Restorative Dent"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2005.76.11.1871"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2005.00831.x"},{"key":"e_1_2_7_31_1","first-page":"398","article-title":"Improved bone regeneration and root coverage using a resorbable membrane with physically assisted cell migration and DFDBA","volume":"20","author":"Dodge JR","year":"2000","journal-title":"Int J Periodontics Restorative Dent"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2003.74.8.1110"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1999.70.9.1077"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2000.71.2.188"},{"key":"e_1_2_7_35_1","first-page":"42","article-title":"Lateral sliding flaps with and without citric acid","volume":"7","author":"Caffesse RG","year":"1987","journal-title":"Int J Periodontics Restorative Dent"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2004.75.1.44"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.1089\/ten.1999.5.53"},{"key":"e_1_2_7_38_1","first-page":"93","article-title":"Biomimetic habitats for cells: Ordered matrix deposition and differentiation in gingival fibroblast cultured on hydroxyapatite coated with a collagen analogue","volume":"9","author":"Bhatnagar RS","year":"1999","journal-title":"Cells Mater"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1996.tb00621.x"},{"key":"e_1_2_7_40_1","first-page":"345","article-title":"Alteration of gingival dimensions in a complicated case of gingival recession","volume":"18","author":"M\u00fcller HP","year":"1998","journal-title":"Int J Periodontics Restorative Dent"},{"key":"e_1_2_7_41_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2009.090187"},{"key":"e_1_2_7_42_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-008-0192-x"},{"key":"e_1_2_7_43_1","first-page":"59","article-title":"Healing of gingival recessions using a collagen membrane with a hemineralized xenograft: A randomized controlled clinical trial","volume":"29","author":"Cardaropoli D","year":"2009","journal-title":"Int J Periodontics Restorative Dent"},{"key":"e_1_2_7_44_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0765.1971.tb00619.x"},{"key":"e_1_2_7_45_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1992.tb01148.x"},{"key":"e_1_2_7_46_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2009.080609"},{"key":"e_1_2_7_47_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1996.67.11.1216"},{"key":"e_1_2_7_48_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2004.75.2.210"},{"key":"e_1_2_7_49_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2004.75.11.1446"},{"key":"e_1_2_7_50_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2000.71.10.1641"},{"key":"e_1_2_7_51_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1997.68.8.770"},{"key":"e_1_2_7_52_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1998.69.11.1271"},{"key":"e_1_2_7_53_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-051x.2000.027001001.x"},{"key":"e_1_2_7_54_1","first-page":"171","article-title":"Failure of root coverage of shallow gingival recessions employing GTR and a bioresorbable membrane","volume":"21","author":"M\u00fcller HP","year":"2001","journal-title":"Int J Periodontics Restorative Dent"},{"key":"e_1_2_7_55_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2004.75.3.413"},{"key":"e_1_2_7_56_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1997.68.10.982"},{"key":"e_1_2_7_57_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1999.70.7.743"}],"container-title":["Journal of Periodontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/pdf\/10.1902\/jop.2010.100434","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T10:27:41Z","timestamp":1760869661000},"score":1,"resource":{"primary":{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/10.1902\/jop.2010.100434"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,5]]},"references-count":56,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2011,5]]}},"alternative-id":["10.1902\/jop.2010.100434"],"URL":"https:\/\/doi.org\/10.1902\/jop.2010.100434","archive":["Portico"],"relation":{},"ISSN":["0022-3492","1943-3670"],"issn-type":[{"type":"print","value":"0022-3492"},{"type":"electronic","value":"1943-3670"}],"subject":[],"published":{"date-parts":[[2011,5]]}}}