{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T21:54:45Z","timestamp":1761947685836,"version":"build-2065373602"},"reference-count":35,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2011,5,1]],"date-time":"2011-05-01T00:00:00Z","timestamp":1304208000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Periodontology"],"published-print":{"date-parts":[[2011,5]]},"abstract":"<jats:p><jats:bold>Background:<\/jats:bold> This meta\u2010analysis investigates the effects of platelet\u2010rich plasma (PRP) on the sinus bone graft.<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold> PubMed, the Cochrane Library, and EMBASE were searched in January 2010.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> Of 61 articles searched, eight controlled clinical trials, which included a total of 352 sinus bone graft cases in 191 patients, were included in the final analysis. In the fixed\u2010effects meta\u2010analysis, the implant survival was not significantly different between two groups in the patient\u2010based data of four studies (relative risk [RR]: 1.02; 95% confidence interval [CI]: 0.97 to 1.08) and in the implant\u2010based data of three studies (RR: 1.02; 95% CI: 0.99 to 1.04). The bone formation was significantly greater in the intervention group in the random\u2010effects model (standardized mean difference [SMD]: 1.30; 95% CI: 0.21 to 2.39) in five studies with significant heterogeneity (I<jats:sup>2<\/jats:sup> = 76.2%). The bone\u2010to\u2010implant contact was not significantly different between two groups in the random\u2010effects model (SMD: 1.02; 95% CI: \u22121.65 to 3.70) in two studies with significant heterogeneity (I<jats:sup>2<\/jats:sup> = 82.4%).<\/jats:p><jats:p><jats:bold>Conclusion:<\/jats:bold> The present study indicates that there was sufficient evidence to support the use of PRP for bone formation on a sinus bone graft, whereas there was no significant effect on the implant survival and bone\u2010to\u2010implant contact.<\/jats:p>","DOI":"10.1902\/jop.2010.100529","type":"journal-article","created":{"date-parts":[[2010,11,23]],"date-time":"2010-11-23T16:26:47Z","timestamp":1290529607000},"page":"660-667","source":"Crossref","is-referenced-by-count":38,"title":["Effects of Platelet\u2010Rich Plasma on Sinus Bone Graft: Meta\u2010Analysis"],"prefix":"10.1002","volume":"82","author":[{"given":"Ji\u2010Hyun","family":"Bae","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Young\u2010Kyun","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seung\u2010Kwon","family":"Myung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,5]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0278-2391(84)90008-9"},{"key":"e_1_2_7_3_1","first-page":"377","article-title":"Sinus augmentation bone grafts for the provision of dental implants: Report of clinical outcome","volume":"18","author":"McCarthy C","year":"2003","journal-title":"Int J Oral Maxillofac Implants"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0722.2008.00571.x"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0011-8532(22)02107-3"},{"key":"e_1_2_7_6_1","first-page":"613","article-title":"Grafting of the maxillary sinus floor with autogenous marrow and bone","volume":"38","author":"Boyne PJ","year":"1980","journal-title":"J Oral Surg"},{"key":"e_1_2_7_7_1","first-page":"843","article-title":"Sinus grafting using platelet\u2010rich plasma \u2013 Initial case presentation","volume":"12","author":"Rosenberg ES","year":"2000","journal-title":"Pract Periodontics Aesthet Dent"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2003.12.003"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1079-2104(98)90029-4"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.id.0000217791.74343.60"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0278-2391(97)90187-7"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0765.2002.01001.x"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-051X.2003.00368.x"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1054\/ijom.2003.0452"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/00001665-200503000-00015"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1089\/ten.2006.12.2555"},{"key":"e_1_2_7_17_1","first-page":"45","article-title":"Effect of platelet\u2010rich plasma on bone growth and osseointegration in human maxillary sinus grafts: Three bilateral case reports","volume":"22","author":"Froum SJ","year":"2002","journal-title":"Int J Periodontics Restorative Dent"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2005.01157.x"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2005.01115.x"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2005.01208.x"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2007.05.023"},{"key":"e_1_2_7_22_1","unstructured":"HigginsJP GreenS.Cochrane Handbook for Systemic Reviews of Interventions.Part 2.8.3 Tools for assessing quality and risk of bias. 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