{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T05:37:35Z","timestamp":1790919455919,"version":"4.1.0"},"reference-count":53,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2011,9,1]],"date-time":"2011-09-01T00:00:00Z","timestamp":1314835200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Periodontology"],"published-print":{"date-parts":[[2011,9]]},"abstract":"<jats:p><jats:bold>Background:<\/jats:bold> The present study aims to compare the performance of minimally invasive non\u2010surgical and surgical approaches for the therapy of intrabony defects.<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold> Twenty\u2010nine patients who presented with intrabony defects were randomly assigned to: 1) a minimally invasive non\u2010surgical technique (MINST) group, or 2) minimally invasive surgical technique (MIST) group. The chair time of each therapeutic procedure was calculated. The probing depth (PD), position of the gingival margin (PGM) and relative clinical attachment level (RCAL) were evaluated at 3 and 6 months after treatments. The patient perception of discomfort\/pain experienced during and after therapy and patient satisfaction regarding treatments were also evaluated.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> Significant PD reductions, RCAL gains, and no changes in the PGM were obtained at 3 and 6 months in MINST and MIST groups (<jats:italic>P<\/jats:italic> &lt;0.05). No differences were observed between groups at any time points (<jats:italic>P<\/jats:italic> &gt;0.05). Patient\u2010oriented outcomes did not demonstrate differences between therapeutic approaches (<jats:italic>P<\/jats:italic> &gt;0.05). Significant higher chair times were required in the MIST group than in the MINST group (<jats:italic>P<\/jats:italic> &lt;0.05).<\/jats:p><jats:p><jats:bold>Conclusions:<\/jats:bold> Minimally invasive non\u2010surgical and surgical approaches were successfully used for the treatment of intrabony defects and achieved periodontal health in association with negligible morbidity and suitable patient satisfaction. However, non\u2010surgical therapeutic modality presented an advantage in terms of a reduction of treatment chair time.<\/jats:p>","DOI":"10.1902\/jop.2011.100680","type":"journal-article","created":{"date-parts":[[2011,2,2]],"date-time":"2011-02-02T03:13:46Z","timestamp":1296616426000},"page":"1256-1266","source":"Crossref","is-referenced-by-count":86,"title":["Clinical and Patient\u2010Centered Outcomes After Minimally Invasive Non\u2010Surgical or Surgical Approaches for the Treatment of Intrabony Defects: A Randomized Clinical Trial"],"prefix":"10.1002","volume":"82","author":[{"given":"Fernanda V.","family":"Ribeiro","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renato C.V.","family":"Casarin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria A.G.","family":"Palma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco H.N.","family":"J\u00fanior","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enilson A.","family":"Sallum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00e1rcio Z.","family":"Casati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,9]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1902\/annals.1996.1.1.37"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1985.tb00940.x"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1996.67.2.93"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2001.72.1.25"},{"issue":"4","key":"e_1_2_7_6_1","first-page":"CD003875","article-title":"Enamel matrix derivative (Emdogain) for periodontal tissue regeneration in intrabony defects","author":"Esposito M","year":"2005","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2006.01020.x"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1987.tb02249.x"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2010.100150"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2007.01144.x"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2008.01242.x"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2008.080190"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2008.080189"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0103-64402010000100010"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2010.100454"},{"key":"e_1_2_7_16_1","first-page":"960","article-title":"Granulation tissue removal in routine and minimally invasive procedures","volume":"16","author":"Harrel SK","year":"1995","journal-title":"Compend Contin Educ Dent"},{"key":"e_1_2_7_17_1","first-page":"3","volume-title":"Minimally Invasive Surgery","author":"Hunter JG","year":"1993"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2005.76.3.380"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0011-8532(22)01190-9"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1995.66.4.261"},{"key":"e_1_2_7_21_1","first-page":"589","article-title":"The simplified papilla preservation flap. A novel surgical approach for the management of soft tissues in regenerative procedures","volume":"19","author":"Cortellini P","year":"1999","journal-title":"Int J Periodontics Restorative Dent"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2009.090393"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1902\/annals.1999.4.1.1"},{"key":"e_1_2_7_24_1","first-page":"229","article-title":"Problems and proposals for recording gingivitis and plaque","volume":"25","author":"Ainamo J","year":"1975","journal-title":"Int Dent J"},{"key":"e_1_2_7_25_1","first-page":"107","article-title":"Gingival sulcus bleeding \u2013 a leading symptom in initial gingivitis","volume":"15","author":"M\u00fchlemann HR","year":"1971","journal-title":"Helv Odontol Acta"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2004.00615.x"},{"key":"e_1_2_7_27_1","first-page":"744","article-title":"Overdentures supported by ITI implants: A 6.5\u2010year evaluation of patient satisfaction and prosthetic aftercare","volume":"10","author":"Wismeyer D","year":"1995","journal-title":"Int J Oral Maxillofac Implants"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-051X.29.s3.5.x"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0757.2004.03797.x"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-051X.2003.00374.x"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2003.74.2.153"},{"issue":"2","key":"e_1_2_7_32_1","first-page":"6","article-title":"Clinical significance of non\u2010surgical periodontal therapy: An evidence\u2010based perspective of scaling and root planing","volume":"29","author":"Cobb CM","year":"2002","journal-title":"J Clin Periodontol"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1984.tb00902.x"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2008.01202.x"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0765.1986.tb01482.x"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1993.tb00355.x"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-051X.2002.291102.x"},{"key":"e_1_2_7_38_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1993.64.10.934"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1988.59.6.351"},{"key":"e_1_2_7_40_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-051X.1997.00833.x"},{"key":"e_1_2_7_41_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2005.00754.x"},{"key":"e_1_2_7_42_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2006.01007.x"},{"key":"e_1_2_7_43_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2003.74.4.521"},{"key":"e_1_2_7_44_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2008.070315"},{"key":"e_1_2_7_45_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2009.080420"},{"key":"e_1_2_7_46_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2006.050302"},{"key":"e_1_2_7_47_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2007.01120.x"},{"key":"e_1_2_7_48_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0757.2004.03681.x"},{"key":"e_1_2_7_49_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-051X.2002.290407.x"},{"key":"e_1_2_7_50_1","first-page":"CD003875","article-title":"Enamel matrix derivative (Emdogain(R)) for periodontal tissue regeneration in intrabony defects","volume":"7","author":"Esposito M","year":"2009","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_7_51_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2000.71.5.752"},{"key":"e_1_2_7_52_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2008.070380"},{"key":"e_1_2_7_53_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2006.060128"},{"key":"e_1_2_7_54_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2009.080637"}],"container-title":["Journal of Periodontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/pdf\/10.1902\/jop.2011.100680","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T10:07:01Z","timestamp":1760868421000},"score":1,"resource":{"primary":{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/10.1902\/jop.2011.100680"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,9]]},"references-count":53,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2011,9]]}},"alternative-id":["10.1902\/jop.2011.100680"],"URL":"https:\/\/doi.org\/10.1902\/jop.2011.100680","archive":["Portico"],"relation":{},"ISSN":["0022-3492","1943-3670"],"issn-type":[{"value":"0022-3492","type":"print"},{"value":"1943-3670","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,9]]}}}