{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T15:55:49Z","timestamp":1778687749422,"version":"3.51.4"},"reference-count":47,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2012,3,1]],"date-time":"2012-03-01T00:00:00Z","timestamp":1330560000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Periodontology"],"published-print":{"date-parts":[[2012,3]]},"abstract":"<jats:p><jats:bold>Background:<\/jats:bold> The aim of this study is to determine in a randomized trial the impact on treatment outcome after 12 months of different subgingival irrigation solutions during scaling and root planing (SRP).<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold> Fifty\u2010one adult volunteers with generalized chronic periodontitis were treated by full\u2010mouth SRP using 0.9% sodium chloride, 0.12% chlorhexidine digluconate, or 7.5% povidone\u2013iodine for subgingival irrigation during SRP. Before SRP and after 3 and 12 months, probing depth (PD), clinical attachment level (CAL), and bleeding on probing (BOP) were recorded. Subgingival plaque samples were analyzed for <jats:italic>Aggregatibacter actinomycetemcomitans<\/jats:italic>, <jats:italic>Porphyromonas gingivalis<\/jats:italic>, <jats:italic>Tannerella forsythia,<\/jats:italic> and <jats:italic>Treponema denticola<\/jats:italic>.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> PD, CAL, and BOP were significantly improved in all groups after 12 months (<jats:italic>P<\/jats:italic> &lt;0.001 to <jats:italic>P<\/jats:italic> = 0.044). No significant differences were seen among the groups for all sites and sites with 4 to 6 mm PD at baseline. The povidone\u2013iodine group had the highest clinical improvements. The counts of <jats:italic>A. actinomycetemcomitans<\/jats:italic> and <jats:italic>P. gingivalis<\/jats:italic> were significantly reduced after 12 months (<jats:italic>P<\/jats:italic> = 0.045 and <jats:italic>P<\/jats:italic> = 0.002) using povidone\u2013iodine. Significant differences between the groups were seen after 3 months for <jats:italic>A. actinomycetemcomitans<\/jats:italic> and <jats:italic>P. gingivalis<\/jats:italic>, and after 12 months for <jats:italic>T. forsythia<\/jats:italic>.<\/jats:p><jats:p><jats:bold>Conclusions:<\/jats:bold> No differences were seen among the groups in the clinical results after 12 months. Regarding the microbiologic results, a slight benefit seemed to derive from the use of povidone\u2013iodine.<\/jats:p>","DOI":"10.1902\/jop.2011.110044","type":"journal-article","created":{"date-parts":[[2011,7,12]],"date-time":"2011-07-12T09:07:06Z","timestamp":1310461626000},"page":"312-320","source":"Crossref","is-referenced-by-count":18,"title":["Clinical and Microbiologic Results 12 Months After Scaling and Root Planing With Different Irrigation Solutions in Patients With Moderate Chronic Periodontitis: A Pilot Randomized Trial"],"prefix":"10.1002","volume":"83","author":[{"given":"Carlos","family":"Kr\u00fcck","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sigrun","family":"Eick","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerhild U.","family":"Kn\u00f6fler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Regina 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