{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T00:26:22Z","timestamp":1760919982707,"version":"build-2065373602"},"reference-count":39,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2012,7,1]],"date-time":"2012-07-01T00:00:00Z","timestamp":1341100800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Periodontology"],"published-print":{"date-parts":[[2012,7]]},"abstract":"<jats:p><jats:bold>Background:<\/jats:bold> This study evaluates the effect of triclosan\/copolymer dentifrice on the 6\u2010month clinical response of patients with generalized severe chronic periodontitis (GSCP) treated with one\u2010stage, full\u2010mouth ultrasonic debridement (FMUD).<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold> Thirty patients diagnosed with GSCP (\u22658 teeth presenting probing depth [PD] \u22655 mm and bleeding on probing [BOP]) were selected and randomly allocated to a control group (n = 15) subjected to FMUD and daily use of a placebo dentifrice or to a test group (n = 15) subjected to FMUD and daily use of a triclosan\/copolymer dentifrice. Patients were analyzed for the following parameters: full\u2010mouth plaque index (FMPI), full\u2010mouth BOP score (FMBS), gingival recession, PD, and clinical attachment level (CAL). Patients were evaluated at 3 and 6 months by a calibrated and masked examiner.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> Initially, the groups presented similar periodontal conditions, with no significant differences in any of the parameters evaluated (<jats:italic>P<\/jats:italic> &gt;0.05). In both groups, improvements in all periodontal parameters (<jats:italic>P<\/jats:italic> &lt;0.05) were seen at the completion of the experimental period. Additionally, the test group showed lower FMPI (3 months) and FMBS (3 and 6 months) than the control group (<jats:italic>P<\/jats:italic> &lt;0.05). Moreover, the CAL gain was significantly greater in the test group, especially at initially deep pockets (PD \u22647 mm). Whereas in the control group the CAL gain in deep pockets was 2.7 \u00b1 0.6 mm, in the test group the CAL gain was 3.6 \u00b1 1.4 mm (<jats:italic>P<\/jats:italic> &lt;0.05).<\/jats:p><jats:p><jats:bold>Conclusion:<\/jats:bold> Within the limits of the present study, the use of triclosan\/copolymer dentifrice promoted additional clinical benefits in the treatment of GSCP treated by one\u2010stage FMUD.<\/jats:p>","DOI":"10.1902\/jop.2011.110348","type":"journal-article","created":{"date-parts":[[2011,11,17]],"date-time":"2011-11-17T02:00:03Z","timestamp":1321495203000},"page":"909-916","source":"Crossref","is-referenced-by-count":8,"title":["Double\u2010Masked Randomized Clinical Trial Evaluating the Effect of a Triclosan\/Copolymer Dentifrice on Periodontal Healing After One\u2010Stage Full\u2010Mouth Debridement"],"prefix":"10.1002","volume":"83","author":[{"given":"Claudia","family":"Pera","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paulo","family":"Ueda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Renato Corr\u00eaa","family":"Viana Casarin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernanda Vieira","family":"Ribeiro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suzana Peres","family":"Pimentel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M\u00e1rcio Zaffalon","family":"Casati","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabiano 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