{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T16:24:26Z","timestamp":1773073466325,"version":"3.50.1"},"reference-count":49,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2013,8,1]],"date-time":"2013-08-01T00:00:00Z","timestamp":1375315200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Periodontology"],"published-print":{"date-parts":[[2013,8]]},"abstract":"<jats:p><jats:bold>Background:<\/jats:bold> Gingival recession (GR) defects can be treated by various methods, including acellular dermal matrix (ADM) or coronally advanced flaps (CAFs). The aim of this histomorphometric experiment is to compare the efficacy of ADM and CAF for treating GR defects in dogs.<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold> In eight beagle dogs, a critical\u2010size labial GR defect was surgically induced on bilateral maxillary cuspids under general anesthesia. Test sites received ADM and CAF, and control sites underwent CAF treatment alone. Plaque index (PI), bleeding index (BI), and gingival index (GI) were measured at 4 weeks (baseline), 8 weeks, and 16 weeks. Width of keratinized gingiva (KG) was determined at baseline and at 16 weeks. Depth of recession and width of GR below the cemento\u2010enamel junction (CEJ) was also determined. After 4 months, animals were sacrificed, and jaw blocks were histomorphometrically assessed for tissue thickness and distance from the stent to the gingival margin (GM) and to the CEJ.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> At 4\u2010, 8\u2010, and 16\u2010week intervals, there was no significant difference in the BI, GI, and PI at the test and control sites. At 16 weeks, thickness of KG was significantly higher at the control sites than test sites (<jats:italic>P<\/jats:italic> &lt;0.01). There was no difference in the midfacial recession depth and recession width at the test and control sites at baseline and before euthanasia (16 weeks). Histomorphometrically, there was no significant difference in tissue thicknesses and distances from the stent to the GM and CEJ in the test and control sites.<\/jats:p><jats:p><jats:bold>Conclusion:<\/jats:bold> ADM might yield similar results to a CAF alone and could decrease the amount of KG.<\/jats:p>","DOI":"10.1902\/jop.2012.120380","type":"journal-article","created":{"date-parts":[[2012,10,22]],"date-time":"2012-10-22T17:24:20Z","timestamp":1350926660000},"page":"1172-1179","source":"Crossref","is-referenced-by-count":8,"title":["Efficacy of Acellular Dermal Matrix and Coronally Advanced Flaps for the Treatment of Induced Gingival Recession Defects: A Histomorphometric Study in Dogs"],"prefix":"10.1002","volume":"84","author":[{"given":"Khalid","family":"Al\u2010Hezaimi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ivan","family":"Rudek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khalid Saleh","family":"Al\u2010Hamdan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fawad","family":"Javed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanna","family":"Iezzi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adriano","family":"Piattelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hom\u2010Lay","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,8]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.2011.0275"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1985.56.12.715"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1973.44.4.248"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1980.51.12.681"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.4103\/0970-9290.42959"},{"issue":"2","key":"e_1_2_6_7_1","first-page":"14","article-title":"Root coverage using the free soft tissue autograft following citric acid application. III. A successful and predictable procedure in areas of deep\u2010wide recession","volume":"5","author":"Miller PD","year":"1985","journal-title":"Int J Periodontics Restorative Dent"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1993.64.4.315"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3913(80)90090-6"},{"key":"e_1_2_6_10_1","first-page":"22","article-title":"The subepithelial connective tissue graft. A new approach to the enhancement of anterior cosmetics","volume":"2","author":"Langer B","year":"1982","journal-title":"Int J Periodontics Restorative Dent"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2011.100586"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2010.100292"},{"key":"e_1_2_6_13_1","first-page":"462","article-title":"Modified coronally positioned flap for obtaining new attachment in Class 2 and 3 furcation defects. Part I: Rationale and surgical technique","volume":"15","author":"Froum SJ","year":"1995","journal-title":"Int J Periodontics Restorative Dent"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1984.55.6.352"},{"key":"e_1_2_6_15_1","unstructured":"AllenEP. AlloDerm: An effective alternative to palatal donor tissue for treatment of gingival recession.Dent Today2006;25:48 50\u201052 quiz 52."},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2006.00969.x"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.4103\/0976-237X.68592"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2001.72.5.571"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2005.76.2.178"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2011.110144"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2004.75.5.734"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2009.080326"},{"key":"e_1_2_6_23_1","first-page":"8","article-title":"A classification of marginal tissue recession","volume":"5","author":"Miller PD","year":"1985","journal-title":"Int J Periodontics Restorative Dent"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2001.72.6.760"},{"key":"e_1_2_6_25_1","first-page":"152","article-title":"Free autogenous gingival grafts. 3. Utilization of grafts in the treatment of gingival recession","volume":"6","author":"Sullivan HC","year":"1968","journal-title":"Periodontics"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2003.74.5.741"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1999.70.9.1077"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1994.65.5.448"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2000.71.2.188"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1999.70.9.1064"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1976.47.5.256"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2001.72.8.998"},{"key":"e_1_2_6_33_1","first-page":"229","article-title":"Problems and proposals for recording gingivitis and plaque","volume":"25","author":"Ainamo J","year":"1975","journal-title":"Int Dent J"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016356309011240"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2001.72.10.1301"},{"key":"e_1_2_6_36_1","doi-asserted-by":"publisher","DOI":"10.1097\/00008505-200101000-00016"},{"key":"e_1_2_6_37_1","first-page":"545","article-title":"Predictability of surgical techniques used for coverage of multiple adjacent gingival recessions \u2014 A systematic review","volume":"43","author":"Hofm\u00e4nner P","year":"2012","journal-title":"Quintessence Int"},{"key":"e_1_2_6_38_1","first-page":"287","article-title":"Comparison of acellular dermal graft and palatal autograft in the reconstruction of keratinized gingiva around dental implants: A case report","volume":"26","author":"Yan JJ","year":"2006","journal-title":"Int J Periodontics Restorative Dent"},{"key":"e_1_2_6_39_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2000.71.8.1297"},{"key":"e_1_2_6_40_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2002.73.3.257"},{"key":"e_1_2_6_41_1","first-page":"378","article-title":"Gingival augmentation with an acellular dermal matrix: Human histologic evaluation of a case \u2014 Placement of the graft on periosteum","volume":"24","author":"Harris RJ","year":"2004","journal-title":"Int J Periodontics Restorative Dent"},{"key":"e_1_2_6_42_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2007.060428"},{"key":"e_1_2_6_43_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2004.75.1.44"},{"key":"e_1_2_6_44_1","first-page":"128","article-title":"Coronally positioned flap with or without acellular dermal matrix graft in gingival recessions: A histometric study","volume":"19","author":"Sallum EA","year":"2006","journal-title":"Am J Dent"},{"key":"e_1_2_6_45_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAJ.0b013e31824d5337"},{"key":"e_1_2_6_46_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2007.070186"},{"key":"e_1_2_6_47_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAJ.0b013e318228283b"},{"key":"e_1_2_6_48_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10266-011-0022-5"},{"key":"e_1_2_6_49_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-481X.2011.00904.x"},{"key":"e_1_2_6_50_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-9657.2011.01019.x"}],"container-title":["Journal of Periodontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/pdf\/10.1902\/jop.2012.120380","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T10:10:53Z","timestamp":1760868653000},"score":1,"resource":{"primary":{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/10.1902\/jop.2012.120380"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,8]]},"references-count":49,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2013,8]]}},"alternative-id":["10.1902\/jop.2012.120380"],"URL":"https:\/\/doi.org\/10.1902\/jop.2012.120380","archive":["Portico"],"relation":{},"ISSN":["0022-3492","1943-3670"],"issn-type":[{"value":"0022-3492","type":"print"},{"value":"1943-3670","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,8]]}}}