{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T23:01:20Z","timestamp":1785366080756,"version":"3.55.0"},"reference-count":32,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2014,3,1]],"date-time":"2014-03-01T00:00:00Z","timestamp":1393632000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001868","name":"National Science Council","doi-asserted-by":"publisher","award":["NSC 99\u20102314\u2010B\u2010038\u2010004\u2010MY3"],"award-info":[{"award-number":["NSC 99\u20102314\u2010B\u2010038\u2010004\u2010MY3"]}],"id":[{"id":"10.13039\/501100001868","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001868","name":"National Science Council","doi-asserted-by":"publisher","award":["NSC 99\u20102323\u2010B\u2010038\u2010003"],"award-info":[{"award-number":["NSC 99\u20102323\u2010B\u2010038\u2010003"]}],"id":[{"id":"10.13039\/501100001868","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Periodontology"],"published-print":{"date-parts":[[2014,3]]},"abstract":"<jats:p><jats:bold>Background:<\/jats:bold> Osteoporosis and periodontitis are both considered global health issues that threaten postmenopausal women and the older population. However, the correlation between osteoporosis and periodontitis is still unclear.<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold> Using a nationwide Taiwanese population\u2010based database, data from patients with osteoporosis (2003 to 2005; n = 2,527) and 7,575 individuals who were matched to each patient by age and sex were analyzed. All participants were tracked for 5 years from the date of enrollment to observe the percentage of patients who developed periodontitis. Cox proportional hazard regressions were performed to evaluate 5\u2010year periodontitis\u2010free survival rates.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> Among the total sample, 3,060 individuals were diagnosed with periodontitis during the 5\u2010year follow\u2010up period: 792 in the study cohort and 2,268 in the comparison cohort. The adjusted hazard ratio for periodontitis in patients with osteoporosis compared with individuals without osteoporosis during the 5\u2010year follow\u2010up was 1.14 (95% confidence interval = 1.05 to 1.24, <jats:italic>P<\/jats:italic> &lt;0.01).<\/jats:p><jats:p><jats:bold>Conclusion:<\/jats:bold> This population\u2010based study indicated that patients with osteoporosis may have an increased risk of periodontitis.<\/jats:p>","DOI":"10.1902\/jop.2013.130256","type":"journal-article","created":{"date-parts":[[2013,9,3]],"date-time":"2013-09-03T14:14:33Z","timestamp":1378217673000},"source":"Crossref","is-referenced-by-count":16,"title":["Population\u2010Based 5\u2010Year Follow\u2010Up Study in Taiwan of Osteoporosis and Risk of Periodontitis"],"prefix":"10.1002","volume":"85","author":[{"given":"Wei\u2010Pin","family":"Chang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei\u2010Chiao","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei\u2010Shin","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jei\u2010Tsung","family":"Pai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuh\u2010Cherng","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ku\u2010Chung","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mu\u2010En","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen\u2010Ta","family":"Chiu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kuo\u2010Sheng","family":"Hung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,3]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.healthpol.2005.04.009"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2007.01121.x"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3913(92)90165-7"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/8756-3282(95)00258-4"},{"key":"e_1_2_7_6_1","first-page":"569","article-title":"NIH Consensus Development Panel on Osteoporosis Prevention, Diagnosis, and Therapy, March 7\u201029, 2000: Highlights of the conference","volume":"94","year":"2001","journal-title":"South Med J"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.4317\/medoral.18298"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2002.73.11.1377"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/039463200802100301"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0105-2896.2005.00334.x"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.4103\/0972-124X.65434"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1875-595X.2003.tb00771.x"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034512457373"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2008.01365.x"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.4317\/medoral.16.e440"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1992.tb01162.x"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s001980050191"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2000.71.9.1492"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0061771"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-012-2185-5"},{"key":"e_1_2_7_21_1","unstructured":"National Center for Health Statistics CDC. 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