{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T17:03:56Z","timestamp":1790442236025,"version":"4.1.0"},"reference-count":28,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2014,10,1]],"date-time":"2014-10-01T00:00:00Z","timestamp":1412121600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Periodontology"],"published-print":{"date-parts":[[2014,10]]},"abstract":"<jats:p><jats:bold>Background:<\/jats:bold> The primary aim is to evaluate clinical, radiographic, and histologic parameters of novel implants with \u201cthree roots\u201d design that were inserted into fresh multirooted extraction sockets. A secondary aim is to compare this new implant to standard root\u2010form dental implants.<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold> Immediate implantation of novel or standard design 6 \u00d7 6\u2010mm implants was performed bilaterally into multirooted sockets in mandibles of mini\u2010pigs. Twelve weeks later, clinical, radiographic, stability, histomorphometric, and microcomputed tomography (micro\u2010CT) analyses were performed.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> Survival rates were significantly higher in the test implants compared with control (92.8% versus 33.3%, respectively; <jats:italic>P<\/jats:italic> &lt;0.001). Bone loss was greater in the control compared with the test by sounding (mean 3.42 \u00b1 0.68 versus 1.96 \u00b1 0.34 mm) and radiography (mean 3.35 \u00b1 0.62 versus 2.27 \u00b1 0.33 mm). Histologic and micro\u2010CT analyses demonstrated bone fill in the inner part of the test implants. Moreover, bone\u2010to\u2010implant contact was higher in the test implants (55.50% \u00b1 3.68% versus 42.47% \u00b1 9.89%). Contrary to the clinical, radiographic, and histomorphometric results, resonance frequency analysis measurements were greater in the control group (77.74 \u00b1 3.21 implant stability quotient [ISQ]) compared with the test group (31.09 \u00b1 0.28 ISQ), <jats:italic>P<\/jats:italic> = 0.008.<\/jats:p><jats:p><jats:bold>Conclusions:<\/jats:bold> The novel design implants resulted in significantly greater survival rate in multirooted extraction sites. Further studies will be required to validate these findings.<\/jats:p>","DOI":"10.1902\/jop.2014.140042","type":"journal-article","created":{"date-parts":[[2014,4,3]],"date-time":"2014-04-03T05:36:34Z","timestamp":1396503394000},"page":"1458-1463","source":"Crossref","is-referenced-by-count":8,"title":["Novel Implant Design Improves Implant Survival in Multirooted Extraction Sites: A Preclinical Pilot Study"],"prefix":"10.1002","volume":"85","author":[{"given":"Adi","family":"Sivan\u2010Gildor","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eli E.","family":"Machtei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eran","family":"Gabay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shai","family":"Frankenthal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liran","family":"Levin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcelo","family":"Suzuki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paulo G.","family":"Coelho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hadar","family":"Zigdon\u2010Giladi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,10]]},"reference":[{"key":"e_1_2_7_2_1","article-title":"Interventions for replacing missing teeth: Different types of dental implants","volume":"4","author":"Esposito M","year":"2007","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2009.01775.x"},{"key":"e_1_2_7_4_1","first-page":"15","article-title":"The role of implant surface modifications, shape and material on the success of osseointegrated dental implants. 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