{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T12:13:00Z","timestamp":1788178380167,"version":"build-2803163510"},"reference-count":42,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2014,9,1]],"date-time":"2014-09-01T00:00:00Z","timestamp":1409529600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100007514","name":"Universit\u00e0 di Pisa","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007514","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Periodontology"],"published-print":{"date-parts":[[2014,9]]},"abstract":"<jats:p><jats:bold>Background:<\/jats:bold> Several materials have been used for ridge preservation after tooth extraction. This 5\u2010year prospective single\u2010cohort study is aimed at evaluating the success rate, marginal bone level (MBL), soft tissue stability, and subjective patient evaluation of implants placed in fresh extraction sockets with the use of a flapless technique and a xenograft to treat the peri\u2010implant bone defect.<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold> Patients requiring a single implant in fresh extraction sockets were selected. After flapless extraction and implant insertion, the peri\u2010implant bone defect was grafted with porcine bone. Collagen membrane was used to stabilize the graft. Four months later, a second surgery and prosthetic procedures were performed. Clinical parameters (width of keratinized gingiva [WKG], facial soft tissue level [FST], papilla index, plaque index, and bleeding on probing) were measured, and periapical radiographs were taken at the time of implant placement (baseline) and then at 1, 3, and 5 years thereafter. Image analysis software was applied to measure changes in the marginal bone level (\u0394MBL). Additionally, patient satisfaction regarding the implant treatment was evaluated. All analyses were collected and measured by an independent, trained observer. Together with descriptive statistics, for each of the outcome variables, pairwise comparisons were performed using the Wilcoxon signed\u2010rank test for matched samples. The level of statistical significance was set at 0.01 for all analyses.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> Forty\u2010seven consecutive patients were treated, with an implant survival rate at 5 years of 95.7%. \u0394MBL showed statistically significant differences: mean values were \u22120.68 \u00b1 0.39, \u22120.94 \u00b1 0.44, and \u22121.08 \u00b1 0.43 mm at the 1, 3, and 5\u2010year follow\u2010up, respectively. Changes in WKG (\u0394WKG) and FST (\u0394FST) decreased from the 1\u2010year point of the survey (0.80 \u00b1 0.79 and 0.71 \u00b1 0.73 mm for \u0394WKG and \u0394FST, respectively) to the last follow\u2010up check at 5 years (0.67 \u00b1 0.74 and 0.56 \u00b1 0.69 mm for \u0394WKG and \u0394FST, respectively), with no significant differences. The papilla indexes showed significant differences among the baseline and all the other time points. Concerning patient satisfaction, at the last survey time point, 74% \u00b1 11.8% of patients were satisfied regarding the overall implant treatment, 73.0% \u00b1 11.1% gave a favorable opinion regarding the appearance of the peri\u2010implant soft tissues, and 80.5% \u00b1 11.3% judged positively the finished appearance of the implant crown. No significant differences were obtained among the three follow\u2010up times.<\/jats:p><jats:p><jats:bold>Conclusions:<\/jats:bold> The data of the present study suggest that the placement of a dental implant by means of a flapless technique in a fresh extraction socket filled with slowly resorbable graft biomaterial and with a delayed prosthetic restoration shows positive final esthetic outcomes. At the 5\u2010year point of the survey, the changes in the bone level were minimal. Moreover, both midfacial tissue and the papillae maintained the early increase recorded before the first year of the follow\u2010up.<\/jats:p>","DOI":"10.1902\/jop.2014.140175","type":"journal-article","created":{"date-parts":[[2014,5,16]],"date-time":"2014-05-16T09:38:09Z","timestamp":1400233089000},"source":"Crossref","is-referenced-by-count":30,"title":["Tissue Stability of Implants Placed in Fresh Extraction Sockets: A 5\u2010Year Prospective Single\u2010Cohort 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