{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T03:29:59Z","timestamp":1787023799266,"version":"build-2736575974"},"reference-count":41,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Periodontology"],"published-print":{"date-parts":[[2015,9]]},"abstract":"<jats:p>\n                    <jats:bold>Background:<\/jats:bold>\n                    A large number of treatments for peri\u2010implantitis are available, but their cost\u2010effectiveness remains uncertain. This study evaluates the cost\u2010effectiveness of preventing and treating peri\u2010implantitis.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Methods:<\/jats:bold>\n                    A Markov model was constructed that followed each implant over 20 years. Supportive implant therapy (SIT) for managing peri\u2010implant mucositis and preventing development of peri\u2010implantitis was either provided or not. Risk of peri\u2010implantitis was assumed to be affected by SIT and the patient's risk profile. If peri\u2010implantitis occurred, 11 treatment strategies (non\u2010surgical or surgical debridement alone or combined with adjunct therapies) were compared. Treatments and risk profiles determined disease progression. Modeling was performed based on systematically collected data. Primary outcomes were costs and proportion of lost implants, as assessed via Monte Carlo microsimulations.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results:<\/jats:bold>\n                    Not providing SIT and performing only non\u2010surgical debridement was both least costly and least effective. The next best (more costly and effective) option was to provide SIT and perform surgical debridement (additional 0.89 euros per 1% fewer implants lost). The most effective option included bone grafts, membranes, and laser treatment (56 euros per 1%). For patients at high risk, the cost\u2010effectiveness of SIT increased, whereas in low\u2010risk groups, a cost\u2010optimized strategy was cost\u2010effective.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusions:<\/jats:bold>\n                    Although clinical decision\u2010making will be guided mainly by clinical condition, cost\u2010effectiveness analyses might add another perspective. Based on these findings, an unambiguous comparative effectiveness ranking was not established. However, cost\u2010effectiveness was predominantly determined by provision of SIT and initial treatment costs. Transferability of these findings to other healthcare systems needs further confirmation.\n                  <\/jats:p>","DOI":"10.1902\/jop.2015.150071","type":"journal-article","created":{"date-parts":[[2015,4,9]],"date-time":"2015-04-09T07:51:46Z","timestamp":1428565906000},"page":"1020-1029","source":"Crossref","is-referenced-by-count":39,"title":["Preventing and Treating Peri\u2010Implantitis: A Cost\u2010Effectiveness Analysis"],"prefix":"10.1002","volume":"86","author":[{"given":"Falk","family":"Schwendicke","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu\u2010Kang","family":"Tu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Stolpe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,9]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2012.02547.x"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2012.02546.x"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0757.1998.tb00124.x"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2008.01274.x"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2012.02541.x"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-051X.29.s3.12.x"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2009.01375.x"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2012.120592"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.12319"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.12333"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2013.11.012"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2011.02309.x"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.12227"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2009.01886.x"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2012.02474.x"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12292"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2012.02542.x"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1708-8208.2011.00384.x"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2013.130563"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12369"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12382"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2011.01837.x"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10389-012-0544-5"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2009.01409.x"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12315"},{"key":"e_1_2_8_27_1","unstructured":"Bundeszahnaerztekammer. Geb\u00fchrenordnung f\u00fcr Zahn\u00e4rzte [in German]. Available atwww.bzaek.de. Accessed July 6 2014."},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/jrsm.1054"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1080\/10618600.1998.10474787"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2011.01844.x"},{"key":"e_1_2_8_31_1","unstructured":"KZBV.Catalogue of Fees [in German]. Available at:http:\/\/www.kzbv.de\/gebuehrenverzeichnisse.334.de.html. Accessed March 2 2014."},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2010.01611.x"},{"key":"e_1_2_8_33_1","unstructured":"Institute for Quality and Efficiency in Health Care.Appraisal of recommendations by the scientific board of IQWiG regarding \u201cMethods to assess cost\u2010effectiveness in German Public Health Insurance\u201d [in German]. Available at:https:\/\/www.iqwig.de\/download\/09\u201003\u201018_Wuerdigung_der_Empfehlung_des_Wissenschaftlichen_Beirats.pdf. Accessed March 4 2014."},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2010.01537.x"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.publhealth.23.100901.140534"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1177\/0272989X98018002S09"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1563\/AAID-JOI-D-10-00086"},{"key":"e_1_2_8_38_1","first-page":"53","article-title":"Peri\u2010implantitis in a specialist clinic of periodontology. Clinical features and risk indicators","volume":"34","author":"Carcuac O","year":"2010","journal-title":"Swed Dent J"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2014.09.013"},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.id.0000148564.88384.de"},{"key":"e_1_2_8_41_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2012.02554.x"},{"key":"e_1_2_8_42_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2008.01618.x"}],"container-title":["Journal of Periodontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/pdf\/10.1902\/jop.2015.150071","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T13:18:11Z","timestamp":1760879891000},"score":1,"resource":{"primary":{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/10.1902\/jop.2015.150071"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,9]]},"references-count":41,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2015,9]]}},"alternative-id":["10.1902\/jop.2015.150071"],"URL":"https:\/\/doi.org\/10.1902\/jop.2015.150071","archive":["Portico"],"relation":{},"ISSN":["0022-3492","1943-3670"],"issn-type":[{"value":"0022-3492","type":"print"},{"value":"1943-3670","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,9]]}}}