{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T17:25:05Z","timestamp":1793985905433,"version":"4.8.0"},"reference-count":62,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,2,1]],"date-time":"2016-02-01T00:00:00Z","timestamp":1454284800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Periodontology"],"published-print":{"date-parts":[[2016,2]]},"abstract":"<jats:p><jats:bold>Background:<\/jats:bold> Immediate implantation, despite many advantages, carries a risk of gingival recession, papilla loss, collapse of ridge contour, and other esthetic complications. Soft tissue graft placement combined with immediate implantation may be used to reduce these concerns. This review aims to systematically analyze clinical esthetic outcomes of the immediate implant combined with soft tissue graft (IMITG).<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold> The PRISMA (Preferred Reporting Items for Systematic Reviews and Meta\u2010Analyses) guidelines for systematic reviews were used. The electronic search was conducted using MEDLINE (PubMed), EMBASE, and Cochrane Central Register of Controlled Trials (CENTRAL) from January 1980 to October 2014. Quality assessments of selected articles were performed. Mid\u2010buccal gingival level, interproximal gingival level, facial gingival thickness, gingival ridge dimension, and width of keratinized gingiva were the esthetic outcomes reviewed. Weighted mean difference of mid\u2010buccal gingival level (WDBGL), papilla index score (WDPIS), and width of keratinized gingiva (WDKG) between initial and last measurements were calculated. Other esthetic outcomes were assessed by the descriptive analysis.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> Ten studies with a minimum of 6\u2010month follow\u2010up were included, and reported esthetic outcomes were analyzed. Mid\u2010buccal gingival level (WDBGL, 0.07 mm; 95% confidence interval [CI] = \u22120.44 to 0.59; <jats:italic>P<\/jats:italic> = 0.12) and interproximal gingival level did not significantly change after IMITG (WDPIS in the mesial site, 0.31; 95% CI = \u22120.01 to 0.64; <jats:italic>P<\/jats:italic> = 0.06; and WDPIS in the distal site, 0.29; 95% CI = \u22120.06 to 0.65; <jats:italic>P<\/jats:italic> = 0.11). Width of keratinized gingiva significantly increased after IMITG (WDKG, 1.27 mm; 95% CI = \u22120.08 to 2.46; <jats:italic>P<\/jats:italic> = 0.04). Facial gingival thickness and gingival ridge dimension could be increased after IMITG.<\/jats:p><jats:p><jats:bold>Conclusions:<\/jats:bold> Because of the heterogeneity and limited number of selected studies, no conclusive statement could be made regarding the benefit of IMITG on esthetic outcomes. More randomized controlled trials are needed to provide definite clinical evidence.<\/jats:p>","DOI":"10.1902\/jop.2015.150383","type":"journal-article","created":{"date-parts":[[2015,10,15]],"date-time":"2015-10-15T12:21:33Z","timestamp":1444911693000},"page":"156-167","source":"Crossref","is-referenced-by-count":46,"title":["The Effect of Subepithelial Connective Tissue Graft Placement on Esthetic Outcomes After Immediate Implant Placement: Systematic Review"],"prefix":"10.1002","volume":"87","author":[{"given":"Chun\u2010Teh","family":"Lee","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chih\u2010Yun","family":"Tao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janet","family":"Stoupel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,2]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2004.00565.x"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2009.01824.x"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2012.01888.x"},{"key":"e_1_2_7_5_1","first-page":"562","article-title":"A prospective randomized clinical study of changes in soft tissue position following immediate and delayed implant placement","volume":"25","author":"Kesteren CJ","year":"2010","journal-title":"Int J Oral Maxillofac Implants"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12276"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1985.56.4.195"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3913(00)70034-5"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1985.56.12.715"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12182"},{"key":"e_1_2_7_11_1","first-page":"12","article-title":"Clinical evaluation of free connective tissue grafts used to increase the width of keratinised gingiva. 1974","volume":"20","author":"Edel A","year":"1998","journal-title":"Periodontal Clin Investig"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1998.tb02466.x"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1902\/annals.2003.8.1.303"},{"key":"e_1_2_7_14_1","first-page":"287","article-title":"Comparison of acellular dermal graft and palatal autograft in the reconstruction of keratinized gingiva around dental implants: A case report","volume":"26","author":"Yan JJ","year":"2006","journal-title":"Int J Periodontics Restorative Dent"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2010.090540"},{"key":"e_1_2_7_16_1","first-page":"11","article-title":"Stability of the mucosal topography around single\u2010tooth implants and adjacent teeth: 1\u2010year results","volume":"20","author":"Grunder U","year":"2000","journal-title":"Int J Periodontics Restorative Dent"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2007.01497.x"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1563\/AAID-JOI-D-13-00043"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1994.65.3.201"},{"key":"e_1_2_7_20_1","first-page":"11","article-title":"A modified surgical\/prosthetic approach for optimal single implant supported crown. 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