{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T16:58:05Z","timestamp":1789750685753,"version":"4.0.1"},"reference-count":27,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2017,9,1]],"date-time":"2017-09-01T00:00:00Z","timestamp":1504224000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Periodontology"],"published-print":{"date-parts":[[2017,9]]},"abstract":"<jats:p><jats:bold>Background:<\/jats:bold> Cortical and cancellous mineralized freeze\u2010dried bone allografts (FDBA) are available for use in alveolar ridge preservation after tooth extraction. There are currently no data regarding use of a combination 50%\/50% cortico\u2010cancellous FDBA compared with a 100% cortical or 100% cancellous FDBA in ridge preservation. The primary objective of this study is to dimensionally and histologically evaluate healing after ridge preservation in non\u2010molar sites using 50%\/50% cortico\u2010cancellous FDBA versus 100% cortical and 100% cancellous FDBA.<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold> Sixty\u2010six patients requiring extraction of a non\u2010molar tooth were enrolled and randomized into three groups to receive ridge preservation with the following: 1) 100% cortical FDBA; 2) 100% cancellous FDBA; or 3) 50%\/50% cortico\u2010cancellous FDBA. After 18 to 20 weeks of healing, a biopsy was harvested, and an implant was placed. The alveolar ridge was measured pre\u2010 and postoperatively to evaluate change in ridge height and width. Percentages of vital bone, residual graft, and connective tissue (CT)\/other were determined via histomorphometric analysis.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> Histomorphometric analysis revealed no significant differences among groups regarding percentage of vital bone or CT\/other. The 100% cortical FDBA group had significantly greater residual graft material (<jats:italic>P<\/jats:italic> = 0.04). Dimensional analysis revealed no significant between\u2010group differences in any parameter measured.<\/jats:p><jats:p><jats:bold>Conclusion:<\/jats:bold> To the best knowledge of the authors, this study offers the first histologic evidence demonstrating no significant difference in vital bone formation or dimensional changes among 50%\/50% cortico\u2010cancellous FDBA, 100% cortical FDBA, and 100% cancellous FDBA when used in ridge preservation of non\u2010molar tooth sites.<\/jats:p>","DOI":"10.1902\/jop.2017.170155","type":"journal-article","created":{"date-parts":[[2017,4,28]],"date-time":"2017-04-28T09:36:33Z","timestamp":1493372193000},"page":"860-868","source":"Crossref","is-referenced-by-count":39,"title":["Histologic Evaluation of Wound Healing After Ridge Preservation With Cortical, Cancellous, and Combined Cortico\u2010Cancellous Freeze\u2010Dried Bone Allograft: A Randomized Controlled Clinical Trial"],"prefix":"10.1002","volume":"88","author":[{"given":"Randy 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