{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,2]],"date-time":"2022-04-02T08:44:27Z","timestamp":1648889067623},"reference-count":0,"publisher":"CIRAD (Centre de Cooperation Internationale en Recherche Agronomique Pour le Developpement)","issue":"2","license":[{"start":{"date-parts":[[1973,2,1]],"date-time":"1973-02-01T00:00:00Z","timestamp":97372800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Elev. Med. Vet. Pays Trop."],"abstract":"<jats:p>Un antis\u00e9rum contre un variant tardif de Trypanosoma congolense n'a montr\u00e9 aucune activit\u00e9 neutralisante sur un type antig\u00e9nique obtenu au d\u00e9but de l'infection, chez un mouton infect\u00e9 cycliquement. Des s\u00e9rums obtenus de rats et souris 10 \u00e0 13 jours apr\u00e8s un traitement st\u00e9rilisant, effectu\u00e9 lors de la premi\u00e8re parasit\u00e9mie apr\u00e8s inoculation de trypanosomes, n'ont pas montr\u00e9 une activit\u00e9 neutralisante suffisamment \u00e9lev\u00e9e contre le type antig\u00e9nique inject\u00e9, pour que cette m\u00e9thode semble int\u00e9ressante pour l'obtention de s\u00e9rums monovalents. Le comportement de la souche utilis\u00e9e n'est en outre pas assez r\u00e9gulier chez le rat (\u00e0 l'oppos\u00e9 de la souris). Un traitement de moutons au B\u00e9r\u00e9nil, \u00e0 forte dose, ne semble pas influencer les r\u00e9sultats de tests de neutralisation effectu\u00e9s avec du s\u00e9rum peu de temps apr\u00e8s le traitement. Quelques observations sur la persistance des anticorps contre diff\u00e9rents types antig\u00e9niques chez des moutons sont donn\u00e9s. Des exp\u00e9riences sur les r\u00e9actions d'agglutination et de lyse avec T. congolense ont abouti \u00e0 des \u00e9checs.<\/jats:p>","DOI":"10.19182\/remvt.7847","type":"journal-article","created":{"date-parts":[[2017,7,8]],"date-time":"2017-07-08T16:00:09Z","timestamp":1499529609000},"page":"147","source":"Crossref","is-referenced-by-count":0,"title":["Etudes immunologiques sur les trypanosomoses. IV. Observations diverses sur Trypanosoma congolense"],"prefix":"10.19182","volume":"26","author":[{"given":"Gerrit","family":"Uilenberg","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michel","family":"Giret","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"8257","published-online":{"date-parts":[[1973,2,1]]},"container-title":["Revue d\u2019\u00e9levage et de m\u00e9decine v\u00e9t\u00e9rinaire des pays tropicaux"],"original-title":[],"link":[{"URL":"http:\/\/revues.cirad.fr\/index.php\/REMVT\/article\/viewFile\/7847\/7841","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/revues.cirad.fr\/index.php\/REMVT\/article\/viewFile\/7847\/7841","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,7,8]],"date-time":"2017-07-08T16:00:10Z","timestamp":1499529610000},"score":1,"resource":{"primary":{"URL":"http:\/\/revues.cirad.fr\/index.php\/REMVT\/article\/view\/7847"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1973,2,1]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[1973,2,1]]}},"URL":"https:\/\/doi.org\/10.19182\/remvt.7847","relation":{},"ISSN":["1951-6711","0035-1865"],"issn-type":[{"value":"1951-6711","type":"electronic"},{"value":"0035-1865","type":"print"}],"subject":[],"published":{"date-parts":[[1973,2,1]]}}}