{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,12]],"date-time":"2025-06-12T12:06:20Z","timestamp":1749729980481,"version":"3.37.0"},"reference-count":0,"publisher":"ALIES","issue":"1","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>The Neocarya macrophylla plant is used traditionally for food, medicinal, spiritual and industrial purposes. It is also used as a soap, dye, glue, fodder, termite repellent, firewood and for structural materials. Few studies on the physicochemical, nutritional content, phytochemical and pharmacological activities have validated the benefits of N. macrophylla to humanity as a food, in cosmetics or pharmaceutical products. The major bioactive constituents identified in the plant so far are steroids and flavonoids, such as, stigmasterol, quercetin, catechin and its related glycosides, as well as glucosamines. Extracts of the plant have shown good antivenom, antimicrobial, analgesic, anti-inflammatory, antimycobacterial, anthelmintic and antioxidant activities. Acute toxicity studies have confirmed the plant to be toxic. More studies on the plant are required in order to exploit other biological activities as claimed by traditional healers and also to isolate more bioactive compounds. In addition, the safety and tolerability assessment of N. macrophylla should be undertaken due to its widespread usage.<\/jats:p>","DOI":"10.19277\/bbr.21.1.331","type":"journal-article","created":{"date-parts":[[2024,5,15]],"date-time":"2024-05-15T17:29:26Z","timestamp":1715794166000},"page":"87-108","source":"Crossref","is-referenced-by-count":1,"title":["Neocarya macrophylla (Chrysobalanaceae): Review of taxonomy, ethnobotany, phytochemistry and biological activities"],"prefix":"10.19277","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4557-859X","authenticated-orcid":false,"given":"Amina","family":"Yusuf Jega","sequence":"first","affiliation":[{"name":"Department of Pharmaceutical and Medicinal Chemistry, Usmanu Danfodiyo University, Sokoto, Nigeria"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9049-9057","authenticated-orcid":false,"given":"Musa Ismail","family":"Abdullahi","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical and Medicinal Chemistry, Usmanu Danfodiyo University, Sokoto, Nigeria"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5083-3017","authenticated-orcid":false,"given":"Abubakar Alhaji","family":"Muhammad","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical and Medicinal Chemistry, Ahmadu Bello University, Zaria, Nigeria"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2119-580X","authenticated-orcid":false,"given":"Kasimu Ghandi","family":"Ibrahim","sequence":"additional","affiliation":[{"name":"- Department of Physiology, College of Health Sciences, Usmanu Danfodiyo University, Sokoto, Nigeria"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6346-5815","authenticated-orcid":false,"given":"Hajara Adamu","family":"Wasagu","sequence":"additional","affiliation":[{"name":"Department of Biology, Shehu Shagari College of Education, Sokoto, Nigeria"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-1873-9884","authenticated-orcid":false,"given":"Florencia Z.","family":"Brauning","sequence":"additional","affiliation":[{"name":"CBIOS - Research Center for Biosciences & Health Technologies, U Lus\u00f3fona, Lisbon, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2545-1812","authenticated-orcid":false,"given":"Gabrielle","family":"Bangay","sequence":"additional","affiliation":[{"name":"Universidad de Alcal\u00e1 de Henares. Facultad de Farmacia, Alcal\u00e1 de Henares, Madrid, Spain"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7992-8343","authenticated-orcid":false,"given":"Patricia","family":"Rijo","sequence":"additional","affiliation":[{"name":"CBIOS - Research Center for Biosciences & Health Technologies, U Lus\u00f3fona, Lisbon, Portugal"}]}],"member":"11182","published-online":{"date-parts":[[2024]]},"container-title":["Biomedical and Biopharmaceutical Research"],"original-title":[],"deposited":{"date-parts":[[2025,2,12]],"date-time":"2025-02-12T14:47:12Z","timestamp":1739371632000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.alies.pt\/BBR%20Editions\/Vol-21-1-2024\/bbr.21.1.331.pdf"}},"subtitle":["Neocarya macrophylla (Chrysobalanaceae): Revis\u00e3o sobre taxonomia, etnobot\u00e2nica, fitoqu\u00edmica e actividades biol\u00f3gicas"],"short-title":[],"issued":{"date-parts":[[2024]]},"references-count":0,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.19277\/bbr.21.1.331","relation":{},"ISSN":["2182-2379"],"issn-type":[{"type":"electronic","value":"2182-2379"}],"subject":[],"published":{"date-parts":[[2024]]}}}