{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,17]],"date-time":"2025-12-17T12:57:46Z","timestamp":1765976266032},"reference-count":0,"publisher":"Ordem dos Medicos","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Med Port"],"abstract":"<jats:p>Introduction: High values of lipoprotein(a), related to atherosclerosis progression, are often considered a marker of thrombosis. We\u00a0assessed the lipoprotein(a) profile in a group of patients with high vascular risk and no cardiovascular events, established its correlation\u00a0with other cardiovascular risk factors and inferred the results for patients with metabolic disorders and, at least, two risk factors.Material and Methods: This longitudinal observational study included 516 patients, who had at least two cardiovascular risk factors and\u00a0regularly attended, for at least two years, the outpatient consultations at a clinic of metabolism and vascular risk for primary prevention.\u00a0Sociodemographic, clinical and anthropometric parameters were obtained at the baseline visit. Hepatic morphology was assessed\u00a0in 509 patients (98.6%) by ultrasonography. The 10-year vascular risk was estimated using Framingham risk score, atherosclerotic\u00a0cardiovascular disease and systematic coronary risk evaluation tables.Results: Significant correlations were found between lipoprotein(a) levels and the addressed vascular risk factors, as well as between lipoprotein(a), and Framingham risk score, atherosclerotic cardiovascular disease and systematic coronary risk evaluation charts.\u00a0Lipoprotein(a) values were also considerably higher in patients with steatosis.Discussion: Increased lipoprotein(a) values were directly associated with all markers of cardiovascular risk and with non-alcoholic\u00a0hepatic steatosis.Conclusion: Due to its high availability and low cost, lipoprotein(a) should become part of the routine evaluation of patients at vascular\u00a0risk.<\/jats:p>","DOI":"10.20344\/amp.10251","type":"journal-article","created":{"date-parts":[[2019,3,29]],"date-time":"2019-03-29T17:42:26Z","timestamp":1553881346000},"page":"202-207","source":"Crossref","is-referenced-by-count":11,"title":["Lipoprotein(a) in the Evaluation of Cardiovascular Risk in the Portuguese Population"],"prefix":"10.20344","volume":"32","author":[{"given":"Joaquim A.","family":"Meireles-Brand\u00e3o","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L\u00facia R.","family":"Meireles-Brand\u00e3o","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rui","family":"Coelho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco R.","family":"Rocha-Gon\u00e7alves","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"8464","published-online":{"date-parts":[[2019,3,29]]},"container-title":["Acta M\u00e9dica Portuguesa"],"original-title":[],"link":[{"URL":"https:\/\/www.actamedicaportuguesa.com\/revista\/index.php\/amp\/article\/download\/10251\/5654","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.actamedicaportuguesa.com\/revista\/index.php\/amp\/article\/download\/10251\/5654","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,10,24]],"date-time":"2022-10-24T22:38:37Z","timestamp":1666651117000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.actamedicaportuguesa.com\/revista\/index.php\/amp\/article\/view\/10251"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,3,29]]},"references-count":0,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2019,3,29]]}},"URL":"https:\/\/doi.org\/10.20344\/amp.10251","relation":{},"ISSN":["1646-0758","0870-399X"],"issn-type":[{"value":"1646-0758","type":"electronic"},{"value":"0870-399X","type":"print"}],"subject":[],"published":{"date-parts":[[2019,3,29]]}}}