{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,10,25]],"date-time":"2022-10-25T04:24:38Z","timestamp":1666671878917},"reference-count":0,"publisher":"Ordem dos Medicos","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Med Port"],"abstract":"<jats:p>O mesotelioma pleural \u00e9 uma doen\u00e7a associada \u00e0 exposi\u00e7\u00e3o ao amianto. Embora raro, \u00e9 a principal neoplasia maligna da pleura, sendo o seu diagn\u00f3stico dif\u00edcil e o seu progn\u00f3stico reservado. O caso cl\u00ednico apresentado refere-se a um doente de 62 anos, do g\u00e9nero masculino, com hist\u00f3ria ocupacional de exposi\u00e7\u00e3o prolongada a amianto e cl\u00ednica arrastada, com meses de evolu\u00e7\u00e3o, de dispneia para pequenos esfor\u00e7os e tosse produtiva. Imagiologicamente, apresentava um envolvimento intersticial extenso com marcado espessamento dos septos interlobulares e centrilobulares, associado a t\u00e9nues altera\u00e7\u00f5es pleurais. V\u00e1rias hip\u00f3teses diagn\u00f3sticas foram equacionadas tais como, asbestose, pneumonia organizativa criptog\u00e9nica, pneumonia intersticial descamativa, met\u00e1stases pleuropulmonares, e\/ou patologia infeciosa broncopulmonar, mas o resultado histol\u00f3gico e imunohistoqu\u00edmico foi compat\u00edvel com mesotelioma pleural- uma neoplasia maligna rara, de origem pleural, com uma taxa de mortalidade elevada.<\/jats:p>","DOI":"10.20344\/amp.11406","type":"journal-article","created":{"date-parts":[[2020,5,15]],"date-time":"2020-05-15T10:16:29Z","timestamp":1589537789000},"page":"143-146","source":"Crossref","is-referenced-by-count":0,"title":["Mesotelioma Intraparenquimatoso Difuso: Uma Apresenta\u00e7\u00e3o Rara"],"prefix":"10.20344","volume":"33","author":[{"given":"Ana","family":"Pais","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicole","family":"Pinto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jo\u00e3o","family":"Cardoso","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manuel","family":"Fernandes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Isabel","family":"Coutinho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Sofia","family":"Oliveira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lurdes","family":"Carvalho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristina","family":"B\u00e1rbara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"8464","published-online":{"date-parts":[[2020,2,3]]},"container-title":["Acta M\u00e9dica Portuguesa"],"original-title":[],"link":[{"URL":"https:\/\/www.actamedicaportuguesa.com\/revista\/index.php\/amp\/article\/download\/11406\/5864","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.actamedicaportuguesa.com\/revista\/index.php\/amp\/article\/download\/11406\/5864","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,10,24]],"date-time":"2022-10-24T20:50:28Z","timestamp":1666644628000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.actamedicaportuguesa.com\/revista\/index.php\/amp\/article\/view\/11406"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2,3]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2020,2,3]]}},"URL":"https:\/\/doi.org\/10.20344\/amp.11406","relation":{},"ISSN":["1646-0758","0870-399X"],"issn-type":[{"value":"1646-0758","type":"electronic"},{"value":"0870-399X","type":"print"}],"subject":[],"published":{"date-parts":[[2020,2,3]]}}}