{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,10,24]],"date-time":"2022-10-24T04:45:19Z","timestamp":1666586719752},"reference-count":0,"publisher":"Ordem dos Medicos","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Med Port"],"abstract":"<jats:p>Os tumores justa-glomerulares s\u00e3o causas raras de hipertens\u00e3o arterial de dif\u00edcil controlo e cursam habitualmente com hipocali\u00e9mia,\u00a0hiperrenin\u00e9mia e hiperaldosteronismo secund\u00e1rio. Descreve-se o caso de uma doente, de 45 anos, com hist\u00f3ria pessoal de hipertens\u00e3o\u00a0arterial de dif\u00edcil controlo associada a hipocali\u00e9mia desde os 35 anos, medicada com quatro classes de anti-hipertensores. Do estudo\u00a0realizado destaca-se hiperaldosteronismo secund\u00e1rio [aldosterona 44,3 ng\/dL (4 - 28 ng\/dL), renina &gt; 1000 mUI\/mL (4,4 - 46,16 mUI\/mL)] e tomografia axial computorizada, que identificou forma\u00e7\u00e3o nodular heterog\u00e9nea localizada no ter\u00e7o m\u00e9dio do rim direito, com\u00a03,7 cm de di\u00e2metro. Foi realizada nefrectomia parcial, cuja an\u00e1lise histol\u00f3gica confirmou o diagn\u00f3stico de reninoma. Ap\u00f3s a cirurgia,\u00a0verificou-se normaliza\u00e7\u00e3o dos doseamentos hormonais (aldosterona 9,2 ng\/dL; renina 1,20 mUI\/mL) e da press\u00e3o arterial. Pretende-se\u00a0chamar a aten\u00e7\u00e3o para esta causa potencialmente cur\u00e1vel de hipertens\u00e3o arterial end\u00f3crina. A ressec\u00e7\u00e3o cir\u00fargica \u00e9 o tratamento de\u00a0escolha e leva \u00e0 normaliza\u00e7\u00e3o da press\u00e3o arterial.<\/jats:p>","DOI":"10.20344\/amp.11660","type":"journal-article","created":{"date-parts":[[2019,11,18]],"date-time":"2019-11-18T21:48:06Z","timestamp":1574113686000},"page":"835-838","source":"Crossref","is-referenced-by-count":0,"title":["Reninoma: Uma Causa Rara de Hipertens\u00e3o End\u00f3crina"],"prefix":"10.20344","volume":"33","author":[{"given":"Bernardo","family":"Marques","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joana","family":"Couto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manuel C.","family":"Lemos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernando","family":"Rodrigues","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"8464","published-online":{"date-parts":[[2020,12,2]]},"container-title":["Acta M\u00e9dica Portuguesa"],"original-title":[],"link":[{"URL":"https:\/\/www.actamedicaportuguesa.com\/revista\/index.php\/amp\/article\/download\/11660\/5705","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.actamedicaportuguesa.com\/revista\/index.php\/amp\/article\/download\/11660\/5705","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,10,23]],"date-time":"2022-10-23T22:26:20Z","timestamp":1666563980000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.actamedicaportuguesa.com\/revista\/index.php\/amp\/article\/view\/11660"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12,2]]},"references-count":0,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2020,12,2]]}},"URL":"https:\/\/doi.org\/10.20344\/amp.11660","relation":{},"ISSN":["1646-0758","0870-399X"],"issn-type":[{"value":"1646-0758","type":"electronic"},{"value":"0870-399X","type":"print"}],"subject":[],"published":{"date-parts":[[2020,12,2]]}}}