{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T22:06:57Z","timestamp":1787954817344,"version":"build-2784847793"},"reference-count":0,"publisher":"Ordem dos Medicos","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Med Port"],"abstract":"<jats:p>Sebaceous carcinoma of the vulva is a rare malignancy of the sebaceous glands, with potentially aggressive behaviour, that is usually\u00a0found in the peri-ocular area. Nonetheless, there are sebaceous glands in the vulva and this diagnosis is especially rare, with only ten\u00a0cases described in the literature. We report a case of 78-year-old female patient who presented with vulvar pruritus, previously treated\u00a0with topical steroid and antifungal treatments, without improvement. The vulvar examination showed a visible yellow papule, 12 x 10\u00a0mm on the right major labia, which was biopsied and the microscopic examination revealed an invasive sebaceous carcinoma of the\u00a0vulva, with an in situ component. We performed an uneventful excisional biopsy, followed by a subsequent margin widening. Three\u00a0months after the diagnosis, she presented with the first recurrence. Two and half years after the diagnosis, she recurred with a larger\u00a0lesion (13 mm) in the upper half of small right lip, more than 10 mm away from the midline. In a multidisciplinary meeting it was decided\u00a0that the patient should undergo partial right vulvectomy with homolateral inguino-femoral sentinel node biopsy (one negative node).\u00a0There was no evidence of recurrence one-year post-surgery.<\/jats:p>","DOI":"10.20344\/amp.13551","type":"journal-article","created":{"date-parts":[[2022,1,3]],"date-time":"2022-01-03T11:34:07Z","timestamp":1641209647000},"page":"63-67","source":"Crossref","is-referenced-by-count":6,"title":["Sebaceous Carcinoma of the Vulva: An Unexpected Diagnosis and Literature Review"],"prefix":"10.20344","volume":"35","author":[{"given":"Ana Carolina","family":"Rocha","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria In\u00eas","family":"S\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos","family":"Abrantes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rita","family":"Sousa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"8464","published-online":{"date-parts":[[2022,1,3]]},"container-title":["Acta M\u00e9dica Portuguesa"],"original-title":[],"link":[{"URL":"https:\/\/www.actamedicaportuguesa.com\/revista\/index.php\/amp\/article\/download\/13551\/6499","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.actamedicaportuguesa.com\/revista\/index.php\/amp\/article\/download\/13551\/6499","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,10,23]],"date-time":"2022-10-23T21:43:36Z","timestamp":1666561416000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.actamedicaportuguesa.com\/revista\/index.php\/amp\/article\/view\/13551"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1,3]]},"references-count":0,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2022,1,3]]}},"URL":"https:\/\/doi.org\/10.20344\/amp.13551","relation":{},"ISSN":["1646-0758","0870-399X"],"issn-type":[{"value":"1646-0758","type":"electronic"},{"value":"0870-399X","type":"print"}],"subject":[],"published":{"date-parts":[[2022,1,3]]}}}