{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T06:02:43Z","timestamp":1747202563461,"version":"3.40.5"},"reference-count":15,"publisher":"Ordem dos Medicos","issue":"12","license":[{"start":{"date-parts":[[2022,5,30]],"date-time":"2022-05-30T00:00:00Z","timestamp":1653868800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Med Port"],"abstract":"<jats:p>Serratia marcescens is a rarely implicated agent in endocarditis. We describe a case of a patient that underwent aortic and mitral valve replacement for Streptococcus agalactiae endocarditis. Four months later, he was readmitted with an ischemic stroke and fever. Physical examination and repetitive transthoracic echocardiogram were unremarkable. The initial blood cultures were negative. Due to sustained fever, vancomycin, gentamicin and piperacillin-tazobactam were initiated. On subsequent blood cultures, Serratia marcescens was isolated and antibiotics switched to ertapenem and gentamicin. In addition to cerebral emboli, a splenic embolus was found. The PET\/CT revealed an abnormal hypercaptation in the mitral bioprosthesis. The patient was treated for six weeks. There are no current specific recommendations regarding the treatment of Serratia marcescens endocarditis. It is widely accepted that treatment should be prolonged and include a combination of antimicrobial agents. Morbidity and mortality are high, particularly when there\u2019s the need for surgical replacement. In this case, however, the patient ended-up only requiring medical treatment due to the favourable response.<\/jats:p>","DOI":"10.20344\/amp.16377","type":"journal-article","created":{"date-parts":[[2022,5,30]],"date-time":"2022-05-30T12:14:52Z","timestamp":1653912892000},"page":"908-912","source":"Crossref","is-referenced-by-count":2,"title":["Serratia marcescens Endocarditis: A Case Report and Literature Review"],"prefix":"10.20344","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7013-3664","authenticated-orcid":false,"given":"Ana Isabel","family":"Ferreira","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernando","family":"Oliveira e Silva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jorge","family":"Reis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marta","family":"Henriques","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jorge","family":"Almeida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"8464","published-online":{"date-parts":[[2022,5,30]]},"reference":[{"doi-asserted-by":"crossref","unstructured":"Phadke VK, Jacob JT. Marvelous but morbid: infective endocarditis due to Serratia marcescens. Infect Dis Clin Pract. 2016,24:143-50.","key":"1296","DOI":"10.1097\/IPC.0000000000000360"},{"doi-asserted-by":"crossref","unstructured":"Yeung HM, Chavarria B, Shahsavari D. A complicated case of Serratia marcescens infective endocarditis in the era of the current opioid epidemic. Case Rep Infect Dis. 2018;2018:5903589.","key":"1297","DOI":"10.1155\/2018\/5903589"},{"doi-asserted-by":"crossref","unstructured":"Korner RJ, Nicol A, Reeves DS, MacGowan AP, Hows J. Ciprofloxacin resistant Serratia marcescens endocarditis as a complication of non-Hodgkin\u2019s lymphoma. J Infect. 1994;29:73\u20136.","key":"1298","DOI":"10.1016\/S0163-4453(94)95141-1"},{"doi-asserted-by":"crossref","unstructured":"Baggish AL, Nadiminti H. Intracranial abscess from embolic Serratia marcescens endocarditis. 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Bilateral endogenous Serratia marcescens endophthalmitis secondary to endocarditis following cardiac surgery. Scott Med J. 2013;58:e1\u20136.","key":"1303","DOI":"10.1177\/0036933013482647"},{"doi-asserted-by":"crossref","unstructured":"Meyer CG, Vacek TP, Bansal A, Gurujal R, Parikh A. Dynamic course of Serratia marcescens pulmonic valve endocarditis resulting in submassive PE and valve replacement. J Investig Med High Impact Case Rep. 2018;26;6:2324709618759128.","key":"1304","DOI":"10.1177\/2324709618759128"},{"doi-asserted-by":"crossref","unstructured":"Nikolakopoulos A, Koutsogiannis N, Xaplanteri P, Gogos C, Kolonitsiou F, Lekkou A. A case of Serratia marcescens endocarditis in a nonintravenous drug-using male patient and review of literature. Case Rep Infect Dis. 2019;20;2019:3715404.","key":"1305","DOI":"10.1155\/2019\/3715404"},{"doi-asserted-by":"crossref","unstructured":"Caceres J, Sood V, Farhat L, Yang B. Aortic valve endocarditis with anomalous origin of the right coronary artery and unknown infected thrombus in the dissected descending thoracic aorta. Aorta. 2020;8:76-9.","key":"1306","DOI":"10.1055\/s-0040-1714715"},{"doi-asserted-by":"crossref","unstructured":"Grinberg S, Bishburg E, Nagarakanti SR. Embolic serratia aortic valve endocarditis. IDCases. 2020;22:e00953.","key":"1307","DOI":"10.1016\/j.idcr.2020.e00953"},{"doi-asserted-by":"crossref","unstructured":"Richardson A, Martinez A, Ghetiya S, Missov E, Percy R, Sattiraju S. Serratia marcescens endocarditis with perivalvular abscess presenting as atrioventricular block. Case Rep Infect Dis. 2020;2020:7463719.","key":"1308","DOI":"10.1155\/2020\/7463719"},{"doi-asserted-by":"crossref","unstructured":"Tan CQ, Chan D, Grant RW, Manganas C. Serratia marcescens infective endocarditis complicated by aortic root abscess and aorta to right atrial fistula. 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