{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T23:31:41Z","timestamp":1770420701868,"version":"3.49.0"},"reference-count":0,"publisher":"Ordem dos Medicos","issue":"10","license":[{"start":{"date-parts":[[2022,7,15]],"date-time":"2022-07-15T00:00:00Z","timestamp":1657843200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Med Port"],"abstract":"<jats:p>O envelhecimento populacional tem-se traduzido no aumento de preval\u00eancia de doen\u00e7as cr\u00f3nicas como a doen\u00e7a renal cr\u00f3nica. A anemia \u00e9 uma das complica\u00e7\u00f5es mais frequentes da doen\u00e7a renal cr\u00f3nica, com impacto n\u00e3o s\u00f3 na qualidade de vida como no progn\u00f3stico do doente e nos custos associados. O conhecimento nesta \u00e1rea terap\u00eautica tem aumentado de forma significativa: desde o aparecimento da eritropoietina recombinante em 1989, passando pelo uso de doses crescentes de ferro parent\u00e9rico e, mais recentemente, a novas mol\u00e9culas como os inibidores do hypoxia-inducible factor. Os autores pretendem rever, de uma forma pragm\u00e1tica, o estado da arte da anemia associada \u00e0 doen\u00e7a renal cr\u00f3nica, desde a epidemiologia, \u00e0 fisiopatologia, ao diagn\u00f3stico e ao tratamento.<\/jats:p>","DOI":"10.20344\/amp.17284","type":"journal-article","created":{"date-parts":[[2022,7,15]],"date-time":"2022-07-15T13:23:34Z","timestamp":1657891414000},"page":"758-764","source":"Crossref","is-referenced-by-count":9,"title":["Anemia da Doen\u00e7a Renal Cr\u00f3nica: O Estado da Arte"],"prefix":"10.20344","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5402-7626","authenticated-orcid":false,"given":"Ana","family":"Farinha","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ant\u00f3nio","family":"Robalo Nunes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jo\u00e3o","family":"Mairos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C\u00e2ndida","family":"Fonseca","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"8464","published-online":{"date-parts":[[2022,7,15]]},"container-title":["Acta M\u00e9dica Portuguesa"],"original-title":[],"link":[{"URL":"https:\/\/actamedicaportuguesa.com\/revista\/index.php\/amp\/article\/download\/17284\/6697","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/actamedicaportuguesa.com\/revista\/index.php\/amp\/article\/download\/17284\/6697","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,10,5]],"date-time":"2022-10-05T08:33:23Z","timestamp":1664958803000},"score":1,"resource":{"primary":{"URL":"https:\/\/actamedicaportuguesa.com\/revista\/index.php\/amp\/article\/view\/17284"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7,15]]},"references-count":0,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2022,10,3]]}},"URL":"https:\/\/doi.org\/10.20344\/amp.17284","relation":{},"ISSN":["1646-0758","0870-399X"],"issn-type":[{"value":"1646-0758","type":"electronic"},{"value":"0870-399X","type":"print"}],"subject":[],"published":{"date-parts":[[2022,7,15]]}}}