{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T19:17:19Z","timestamp":1770837439734,"version":"3.50.1"},"reference-count":17,"publisher":"Ordem dos Medicos","issue":"2","license":[{"start":{"date-parts":[[2023,1,16]],"date-time":"2023-01-16T00:00:00Z","timestamp":1673827200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Med Port"],"abstract":"<jats:p>Introduction: Salmonellosis represents a considerable health, social and economic burden in both high- and low-income countries. Recently, in Portugal, most cases of Salmonella infections have been reported in children under 15 years of age. The main aim of this study was to characterize, from an epidemiological, microbiological, and clinical perspective, cases of Salmonella isolation among children.Material and Methods: The authors performed a descriptive study using retrospective analysis of cases of salmonellosis, in pediatric age, at a Portuguese Level II Hospital, between January 2015 and July 2020. Results: The population included a total of 63 children, of which 81% were Portuguese. Ethnicity was identified in 13 children, most of whom were African. The median age at diagnosis was four years old (3.5 - 9 years old). Despite the small number of cases per year in our study (11), one-third were severe enough to require hospitalization. Overall, 13% of patients were treated with antibiotics. In 63% of the isolates, serotype was identified: Salmonella Enteriditis (38%), Salmonella Typhimurium (22%), and Salmonella Typhi (3%). Antibiotic resistance rates were 19% for ampicillin and 6.4% for amoxicillinclavulanic acid and cotrimoxazole. No resistance to third-generation cephalosporins was found.Conclusion: Given the obtained results, we intend to improve knowledge on salmonellosis in Portugal and, consequently improve prevention strategies, treatment and its notification. Although the incidence of salmonellosis has been decreasing in recent years it is the second most frequent gastrointestinal infection in the European Union, contributing to significant rates of hospitalizations and use of antibiotics in Portugal.<\/jats:p>","DOI":"10.20344\/amp.18906","type":"journal-article","created":{"date-parts":[[2023,1,16]],"date-time":"2023-01-16T22:43:36Z","timestamp":1673909016000},"page":"96-104","source":"Crossref","is-referenced-by-count":5,"title":["Salmonellosis in Children at a Portuguese Hospital: A Retrospective Study"],"prefix":"10.20344","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4324-3606","authenticated-orcid":false,"given":"In\u00eas Filipa","family":"Mendes","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara","family":"Completo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rita","family":"Vieira de Carvalho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandra","family":"Jacinto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandra","family":"Sch\u00e4fer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paula","family":"Correia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Jo\u00e3o","family":"Brito","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ant\u00f3nio","family":"Figueiredo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"8464","published-online":{"date-parts":[[2023,1,16]]},"reference":[{"key":"1760","doi-asserted-by":"publisher","DOI":"10.1111\/jpc.13585"},{"key":"1761","unstructured":"Pinto CS, Bordalo A, Albuquerque MJ, Nascimento M, Vic\u00eancio PO. Doen\u00e7as de declara\u00e7\u00e3o obrigat\u00f3ria 2011-2014. Lisboa: Dire\u00e7\u00e3o-Geral da Sa\u00fade; 2015."},{"key":"1762","doi-asserted-by":"publisher","DOI":"10.1542\/pir.2017-0198"},{"key":"1763","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00002-15"},{"key":"1764","doi-asserted-by":"crossref","unstructured":"Haeusler GM, Curtis N. Non-typhoidal Salmonella in children: microbiology, epidemiology and treatment. Adv Exp Med Biol. 2013;764:13-26.","DOI":"10.1007\/978-1-4614-4726-9_2"},{"key":"1765","unstructured":"American Academy of Pediatrics. Salmonella infections. In: Pickering LK, Baker CJ, Kimberlin DW, Long SS, editors. Red Book: 2012 Report of the Committee on Infectious Diseases. 29th ed. Elk Grove Village: AAC; 2012. p. 584\u20138."},{"key":"1766","doi-asserted-by":"publisher","DOI":"10.20344\/amp.145"},{"key":"1767","unstructured":"Pignatelli D, Leal E, Lito D, D\u00e2maso C, Rodrigues M, Cunha F. Gastroenterite aguda por Salmonella n\u00e3o tifoide em crian\u00e7as: revis\u00e3o de 10 anos. Acta Pediatr Port. 2014;45:204-9."},{"key":"1768","unstructured":"European Centre for Disease Prevention and Control. Salmonellosis. In: ECDC. Annual epidemiological report for 2017. Stockholm: ECDC; 2020."},{"key":"1769","unstructured":"Rodrigues F, Alves MC, Alves AF, Lemos L. Etiologia das gastroenterites agudas em unidade de internamento de curta dura\u00e7\u00e3o: estudo prospectivo de 12 meses. Acta Pediatr Port. 2007;38:13-7."},{"key":"1770","unstructured":"Silveira L, Pista A, Machado J. Caracteriza\u00e7\u00e3o fenot\u00edpica de isolados de Salmonella ent\u00e9rica recebidos no INSA entre 2014 e 2017. Bol Epidemiol Observa\u00e7\u00f5es. 2018;7:49-51."},{"key":"1771","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.37.12.4177-4178.1999"},{"key":"1772","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4614-4726-9_2"},{"key":"1773","unstructured":"Centers for Disease Control and Prevention. National Salmonella Surveilance Overview. Atlanta: CDC; 2011."},{"key":"1774","unstructured":"Autoridade de Seguran\u00e7a Alimentar e Econ\u00f3mica. Salmonella. [cited 2022 Jan 10]. Available from: https:\/\/www.asae.gov.pt\/?cn=541054135462aaaaaaaaaaaa."},{"key":"1775","unstructured":"Francisco C. Salmonelose em humanos. Coimbra: Universidade de Coimbra; 2016."},{"key":"1776","unstructured":"Sociedade Portuguesa de Medicina do Viajante. Recomenda\u00e7\u00f5es vacinas - Edi\u00e7\u00e3o 01\/2018. Grupo de Trabalho de Vacinas da SPMV. 2018. [cited 2022 Sep 05]. Available from: https:\/\/spmv.simposium.pt\/media\/13961\/Recomendacoes"}],"container-title":["Acta M\u00e9dica Portuguesa"],"original-title":[],"link":[{"URL":"https:\/\/www.actamedicaportuguesa.com\/revista\/index.php\/amp\/article\/download\/18906\/15022","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.actamedicaportuguesa.com\/revista\/index.php\/amp\/article\/download\/18906\/15022","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,17]],"date-time":"2025-04-17T14:34:47Z","timestamp":1744900487000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.actamedicaportuguesa.com\/revista\/index.php\/amp\/article\/view\/18906"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1,16]]},"references-count":17,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2023,2,1]]}},"URL":"https:\/\/doi.org\/10.20344\/amp.18906","relation":{},"ISSN":["1646-0758","0870-399X"],"issn-type":[{"value":"1646-0758","type":"electronic"},{"value":"0870-399X","type":"print"}],"subject":[],"published":{"date-parts":[[2023,1,16]]}}}