{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,1,3]],"date-time":"2025-01-03T05:16:56Z","timestamp":1735881416669,"version":"3.32.0"},"reference-count":15,"publisher":"Ordem dos Medicos","issue":"1","license":[{"start":{"date-parts":[[2025,1,2]],"date-time":"2025-01-02T00:00:00Z","timestamp":1735776000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Med Port"],"abstract":"<jats:p>O Haemophilus influenzae serotipo A \u00e9 uma causa rara de meningite e doen\u00e7a invasiva em idade pedi\u00e1trica. Um lactente de seis meses deu entrada no servi\u00e7o de urg\u00eancia por quadro de febre, tosse e rinorreia. \u00c0 admiss\u00e3o, encontrava-se v\u00edgil e hemodinamicamente est\u00e1vel, tendo ficado progressivamente let\u00e1rgico e com abaulamento da fontanela. As an\u00e1lises sangu\u00edneas mostraram contagem leucocit\u00e1ria normal e prote\u00edna C reativa elevada. A citologia e bioqu\u00edmica do l\u00edquido c\u00e9falo-raquidiano foram compat\u00edveis com meningite bacteriana, tendo iniciado terap\u00eautica com ceftriaxone. A hemocultura e exame cultural do l\u00edquido c\u00e9falo-raquidiano foram positivos para Haemophilus influenzae. A serotipagem da estirpe identificou um Haemophilus influenzae serotipo A. As pesquisas de v\u00edrus no l\u00edquido c\u00e9falo-raquidiano e no aspirado nasofar\u00edngeo foram positivas para adenov\u00edrus. Teve alta ap\u00f3s 10 dias de antibi\u00f3tico e recupera\u00e7\u00e3o cl\u00ednica completa. Embora os casos de meningite por Haemophilus influenzae serotipo A sejam raros, a doen\u00e7a invasiva por serotipos n\u00e3o-B e n\u00e3o capsulados tem aumentado, refor\u00e7ando a necessidade de monitoriza\u00e7\u00e3o e vigil\u00e2ncia epidemiol\u00f3gica.<\/jats:p>","DOI":"10.20344\/amp.21725","type":"journal-article","created":{"date-parts":[[2025,1,2]],"date-time":"2025-01-02T11:44:26Z","timestamp":1735818266000},"page":"49-51","source":"Crossref","is-referenced-by-count":0,"title":["Meningite a Haemophilus influenzae Serotipo A e por Adenov\u00edrus: Caso Raro de Coinfe\u00e7\u00e3o em Lactente de Seis Meses"],"prefix":"10.20344","volume":"38","author":[{"given":"In\u00eas","family":"Mazeda","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joana","family":"Ventura Louren\u00e7o","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Nascimento Moreira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gracinda","family":"Oliveira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabel","family":"Mendes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"8464","published-online":{"date-parts":[[2025,1,2]]},"reference":[{"key":"7851","doi-asserted-by":"crossref","unstructured":"Bajanca-Lavado MP, Cavaco L, Fernandes M, Touret T, Candeias C, Sim\u00f5es AS, et al. 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