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A apropriada estratifica\u00e7\u00e3o inicial dos doentes permite otimizar a sele\u00e7\u00e3o e a sequ\u00eancia da terap\u00eautica, assim como o correto seguimento durante o tratamento, com impacto na sobreviv\u00eancia. As presentes recomenda\u00e7\u00f5es laboratoriais do Grupo Portugu\u00eas do Mieloma M\u00faltiplo oferecem orienta\u00e7\u00f5es para o diagn\u00f3stico e seguimento laboratorial dos doentes com mieloma m\u00faltiplo. O seguimento e diagn\u00f3stico de doentes com outras gamapatias monoclonais de significado cl\u00ednico n\u00e3o foram inclu\u00eddos neste texto. 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