{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T06:06:02Z","timestamp":1770098762542,"version":"3.49.0"},"reference-count":43,"publisher":"Ordem dos Medicos","issue":"2","license":[{"start":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T00:00:00Z","timestamp":1767916800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Med Port"],"abstract":"<jats:p>O tromboembolismo venoso \u00e9 uma complica\u00e7\u00e3o frequente em doentes oncol\u00f3gicos, sobretudo em fases avan\u00e7adas, nas quais a presen\u00e7a de doen\u00e7a metast\u00e1tica pode aumentar o risco de trombose em cerca de 20 vezes relativamente aos est\u00e1dios iniciais, sendo esse risco ainda mais acentuado nos doentes em fim de vida. Apesar da elevada preval\u00eancia, persistem lacunas significativas na evid\u00eancia que orienta a sua gest\u00e3o nesta fase da doen\u00e7a. A abordagem do tromboembolismo venoso nesta popula\u00e7\u00e3o representa um desafio terap\u00eautico, dada a elevada taxa de recorr\u00eancia tromb\u00f3tica e de complica\u00e7\u00f5es hemorr\u00e1gicas. Adicionalmente, o diagn\u00f3stico \u00e9 dificultado tanto pela inespecificidade dos sintomas como pela necessidade de evitar exames invasivos ou onerosos, que possam comprometer o conforto do doente. Este manuscrito, desenvolvido em colabora\u00e7\u00e3o entre o Grupo de Estudos de Cancro e Trombose e a Associa\u00e7\u00e3o Portuguesa de Cuidados Paliativos, rev\u00ea os principais desafios cl\u00ednicos e \u00e9ticos associados ao diagn\u00f3stico, tratamento e profilaxia do tromboembolismo venoso nesta popula\u00e7\u00e3o, com o intuito de apoiar a pr\u00e1tica m\u00e9dica em decis\u00f5es muitas vezes complexas. As recomenda\u00e7\u00f5es aqui propostas baseiam-se na melhor evid\u00eancia dispon\u00edvel, complementada pela experi\u00eancia cl\u00ednica dos autores e por uma reflex\u00e3o \u00e9tica centrada no doente. S\u00e3o apresentados crit\u00e9rios para orientar i) a decis\u00e3o de iniciar, manter ou suspender anticoagula\u00e7\u00e3o; ii) o papel da imagiologia neste contexto; iii) as indica\u00e7\u00f5es para a tromboprofilaxia. Com esta s\u00edntese, pretende-se contribuir para uma pr\u00e1tica mais informada e consistente, com foco na qualidade de vida e dignidade do doente, refor\u00e7ando a qualidade dos cuidados prestados e promovendo a sua aplica\u00e7\u00e3o transversal nos diferentes contextos assistenciais.<\/jats:p>","DOI":"10.20344\/amp.24007","type":"journal-article","created":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T16:38:39Z","timestamp":1767976719000},"page":"149-157","source":"Crossref","is-referenced-by-count":0,"title":["Recomenda\u00e7\u00f5es para a Abordagem do Tromboembolismo Venoso no Doente Oncol\u00f3gico em Fim de Vida: Consenso Nacional"],"prefix":"10.20344","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-1721-3127","authenticated-orcid":false,"given":"Natacha","family":"Mour\u00e3o","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9150-4180","authenticated-orcid":false,"given":"Joana","family":"Liz-Pimenta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ricardo","family":"Pinto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2100-5831","authenticated-orcid":false,"given":"Ricardo","family":"Fernandes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2411-3993","authenticated-orcid":false,"given":"Jo\u00e3o","family":"Godinho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9356-3536","authenticated-orcid":false,"given":"Nuno","family":"Teixeira Tavares","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6625-5183","authenticated-orcid":false,"given":"Michael","family":"Lu\u00eds","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6200-6959","authenticated-orcid":false,"given":"Mariana","family":"Malheiro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dialina","family":"Brilhante","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jo\u00e3o","family":"Pacheco Pereira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S\u00e9rgio","family":"Barroso","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-2310-5627","authenticated-orcid":false,"given":"Joana","family":"Augusto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1968-9237","authenticated-orcid":false,"given":"Miguel","family":"Barbosa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1123-1635","authenticated-orcid":false,"given":"Teresa","family":"Sarmento","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"8464","published-online":{"date-parts":[[2026,1,9]]},"reference":[{"key":"11899","doi-asserted-by":"publisher","DOI":"10.1016\/j.thromres.2009.12.023"},{"key":"11900","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.164.15.1653"},{"key":"11901","doi-asserted-by":"publisher","DOI":"10.1111\/jth.12338"},{"key":"11902","unstructured":"Farge D, Frere C, Connors JM, Ay C, Khorana AA, Munoz A, et al. 2022 International clinical practice guidelines for the treatment and prophylaxis of venous thromboembolism in patients with cancer. 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