{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T02:31:15Z","timestamp":1792290675583,"version":"4.4.0"},"reference-count":11,"publisher":"Ordem dos Medicos","issue":"8","license":[{"start":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T00:00:00Z","timestamp":1779667200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Med Port"],"abstract":"<jats:p>A tomografia por emiss\u00e3o de positr\u00f5es (PET) com fluorodesoxiglicose {[18F]FDG} \u00e9 um exame utilizado para identificar \u00e1reas de metabolismo glicol\u00edtico aumentado, auxiliando no diagn\u00f3stico, estadiamento e seguimento de patologia neopl\u00e1sica, infeciosa ou inflamat\u00f3ria. Em pessoas com diabetes mellitus (DM), a hiperglicemia e a hiperinsulinemia alteram a biodistribui\u00e7\u00e3o do radiof\u00e1rmaco, comprometendo a precis\u00e3o diagn\u00f3stica deste exame. A aus\u00eancia de normas claras pode resultar na prepara\u00e7\u00e3o inadequada do doente e necessidade de adiar ou repetir o mesmo, acarretando preju\u00edzo para o doente e para a institui\u00e7\u00e3o. Este protocolo de atua\u00e7\u00e3o cl\u00ednica resulta de uma revis\u00e3o da evid\u00eancia dispon\u00edvel e de um processo de consenso multidisciplinar entre os servi\u00e7os de Endocrinologia e de Medicina Nuclear da Unidade Local de Sa\u00fade S\u00e3o Jo\u00e3o, visando estabelecer recomenda\u00e7\u00f5es aplic\u00e1veis ao contexto hospitalar portugu\u00eas. O documento inclui recomenda\u00e7\u00f5es detalhadas sobre a gest\u00e3o dos f\u00e1rmacos antidiab\u00e9ticos previamente \u00e0 realiza\u00e7\u00e3o de PET com [18F]FDG, encontrando-se organizado por cen\u00e1rios cl\u00ednicos espec\u00edficos: 1) DM tipo 2; 2) DM tipo 1, incluindo doentes com sistemas de perfus\u00e3o subcut\u00e2nea cont\u00ednua de insulina; e 3) DM secund\u00e1ria a corticoterapia. No caso de hiperglicemia de 200 - 350 mg\/dL no dia do exame, o protocolo contempla a administra\u00e7\u00e3o de insulina de acordo com um esquema personalizado, adaptado ao \u00edndice de massa corporal e fun\u00e7\u00e3o renal. A implementa\u00e7\u00e3o deste protocolo visa uniformizar a prepara\u00e7\u00e3o de pessoas com diabetes para a realiza\u00e7\u00e3o de PET com [18F]FDG e minimizar a necessidade de adiar ou repetir exames, permitindo a otimiza\u00e7\u00e3o da gest\u00e3o de recursos hospitalares.<\/jats:p>","DOI":"10.20344\/amp.24274","type":"journal-article","created":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T16:07:13Z","timestamp":1779725233000},"page":"486-491","source":"Crossref","is-referenced-by-count":1,"title":["Gest\u00e3o da Terap\u00eautica Antidiab\u00e9tica em Doentes Submetidos a PET com [18F]FDG"],"prefix":"10.20344","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3925-1750","authenticated-orcid":false,"given":"Helena","family":"Urbano Ferreira","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-0405-1268","authenticated-orcid":false,"given":"Mafalda","family":"Canudas Costa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2929-3751","authenticated-orcid":false,"given":"Marta","family":"Canha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisabete","family":"Rodrigues","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-9619-9809","authenticated-orcid":false,"given":"Maria do Sameiro","family":"Lemos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7692-0343","authenticated-orcid":false,"given":"Paula","family":"Soeiro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0495-8219","authenticated-orcid":false,"given":"Maria Teresa","family":"Faria","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joana","family":"Queir\u00f3s","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"8464","published-online":{"date-parts":[[2026,5,25]]},"reference":[{"key":"12966","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-014-2961-x"},{"key":"12967","doi-asserted-by":"publisher","DOI":"10.2967\/jnmt.113.132621"},{"key":"12968","doi-asserted-by":"publisher","DOI":"10.4103\/ijnm.IJNM_151_19"},{"key":"12969","doi-asserted-by":"publisher","DOI":"10.1097\/MNM.0000000000000082"},{"key":"12970","unstructured":"Hern\u00e1ndez Grimaldo EG. Impacto de la terapia intravenosa con insulina de corta acci\u00f3n en la biodistribuci\u00f3n del 18F-FDG en PET\/CT de pacientes con hiperglucemia detectada incidentalmente. Nuevo Le\u00f3n: Universidad Aut\u00f3noma de Nuevo Le\u00f3n; 2023."},{"key":"12971","doi-asserted-by":"publisher","DOI":"10.1186\/s13550-019-0480-2"},{"key":"12972","doi-asserted-by":"publisher","DOI":"10.2967\/jnumed.108.056283"},{"key":"12973","unstructured":"Duarte DS, Violante L, Torres I, Duarte H. Tomografia por emiss\u00e3o de positr\u00f5es com [18F]-FDG e diabetes mellitus \u2013 protocolo de abordagem. 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