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O uso sistem\u00e1tico da tomografia \u00e9 consensual como ferramenta de diagn\u00f3stico nos casos moderados ou graves, mas permanece controverso nos casos ligeiros. Nos \u00faltimos anos, os biomarcadores s\u00e9ricos emergem como uma ferramenta objetiva e complementar na estratifica\u00e7\u00e3o do risco de les\u00e3o. A prote\u00edna \u00e1cida fibrilar glial e a ubiquitina C-terminal hidrolase L1 auxiliam a tomada de decis\u00e3o em doentes com escala de coma de Glasgow entre 14 e 15 nas primeiras 12 horas ap\u00f3s trauma. Neste consenso, pretende-se estabelecer um algoritmo de decis\u00e3o baseado na conjuga\u00e7\u00e3o de scores cl\u00ednicos como o Canadian CT Head Rule (elevada sensibilidade) e biomarcadores. O algoritmo tem como principal objetivo homogeneizar a abordagem, baseando-se na evid\u00eancia e procurando reduzir a exposi\u00e7\u00e3o a radia\u00e7\u00f5es e a perman\u00eancia no servi\u00e7o de urg\u00eancia, promovendo, em simult\u00e2neo, altas com seguran\u00e7a cl\u00ednica. Nos casos de risco moderado, quando a prote\u00edna \u00e1cida fibrilar glial e a ubiquitina C-terminal hidrolase L1 s\u00e3o negativas nas primeiras 12 h ap\u00f3s trauma, a necessidade de tomografia computorizada cr\u00e2nio-encef\u00e1lica \u00e9 exclu\u00edda pelo elevado valor preditivo negativo destes biomarcadores, permitindo a alta salvo outra indica\u00e7\u00e3o cl\u00ednica. Todos os doentes de alto risco far\u00e3o tomografia computorizada cr\u00e2nio-encef\u00e1lica, os sob terap\u00eautica antitromb\u00f3tica adicionalmente biomarcadores: ambos resultados negativos permitem considerar alta; ambos resultados positivos implicam admiss\u00e3o, se tomografia computorizada negativa e pelo menos um dos biomarcadores positivo sugere-se: repeti\u00e7\u00e3o da tomografia computorizada cr\u00e2nio-encef\u00e1lica em doentes com idade igual ou superior a 75 anos, em virtude de valores elevados s\u00e9ricos mesmo na aus\u00eancia de trauma em 95% deste subgrupo e da inexist\u00eancia \u00e0 data de cut-offs ajustados \u00e0 idade; devem repetir-se biomarcadores se idade inferior a 75 anos. Pretende-se ainda dar a conhecer uma nova proposta de classifica\u00e7\u00e3o do traumatismo cr\u00e2nio-encef\u00e1lico que visa uma caracteriza\u00e7\u00e3o mais completa e individualizada.<\/jats:p>","DOI":"10.20344\/amp.24437","type":"journal-article","created":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T15:38:25Z","timestamp":1784561905000},"source":"Crossref","is-referenced-by-count":0,"title":["Traumatismo Cr\u00e2nio-Encef\u00e1lico Ligeiro: Recomenda\u00e7\u00f5es Cl\u00ednicas de Consenso Nacional"],"prefix":"10.20344","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7154-5943","authenticated-orcid":false,"given":"Filipa","family":"Ferreira","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-0421-4523","authenticated-orcid":false,"given":"Armando","family":"Lopes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5701-2737","authenticated-orcid":false,"given":"Carla","family":"Freitas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-0945-5545","authenticated-orcid":false,"given":"Carolina","family":"Domingues","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-4902-4951","authenticated-orcid":false,"given":"Helena","family":"Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-0444-8597","authenticated-orcid":false,"given":"In\u00eas","family":"Nunes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9128-7064","authenticated-orcid":false,"given":"Jo\u00e3o","family":"Lemos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3496-1710","authenticated-orcid":false,"given":"Jorge","family":"Pereira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4030-2874","authenticated-orcid":false,"given":"Jos\u00e9 Lu\u00eds","family":"Alves","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0692-4848","authenticated-orcid":false,"given":"Adelina","family":"Pereira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"8464","published-online":{"date-parts":[[2026,7,20]]},"reference":[{"key":"13169","doi-asserted-by":"crossref","unstructured":"Capizzi A, Woo J, Verduzco-Gutierrez M. 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