{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,15]],"date-time":"2025-04-15T11:34:48Z","timestamp":1744716888499},"reference-count":0,"publisher":"Ordem dos Medicos","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Med Port"],"abstract":"<jats:p>O penfigoide bolhoso \u00e9 uma doen\u00e7a autoimune caracterizada pela forma\u00e7\u00e3o de bolhas subepid\u00e9rmicas. Pode ser autolimitada mas\u00a0quando necess\u00e1rio o tratamento passa pelo uso de corticoides, imunossupressores, e em \u00faltima linha agentes biol\u00f3gicos. Apresenta-se\u00a0o caso de um doente de 37 anos com penfigoide bolhoso com uma forma de apresenta\u00e7\u00e3o grave e refrat\u00e1ria. Ap\u00f3s cerca de um\u00a0m\u00eas de tratamento com v\u00e1rios f\u00e1rmacos de primeira linha, por aus\u00eancia de resposta, optou-se por iniciar rituximab com franca melhoria\u00a0das les\u00f5es. Os autores pretendem real\u00e7ar a utilidade e efic\u00e1cia deste f\u00e1rmaco nesta patologia.<\/jats:p>","DOI":"10.20344\/amp.7812","type":"journal-article","created":{"date-parts":[[2017,4,17]],"date-time":"2017-04-17T16:25:51Z","timestamp":1492446351000},"page":"243-246","source":"Crossref","is-referenced-by-count":4,"title":["Penfigoide Bolhoso Tratado com Sucesso com Rituximab"],"prefix":"10.20344","volume":"30","author":[{"given":"Nuno","family":"Silva","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreia","family":"Costa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernando","family":"Salvador","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisa","family":"Serradeiro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"8464","published-online":{"date-parts":[[2017,3,31]]},"container-title":["Acta M\u00e9dica Portuguesa"],"original-title":[],"link":[{"URL":"https:\/\/www.actamedicaportuguesa.com\/revista\/index.php\/amp\/article\/download\/7812\/4974","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.actamedicaportuguesa.com\/revista\/index.php\/amp\/article\/download\/7812\/4974","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,10,25]],"date-time":"2022-10-25T20:51:56Z","timestamp":1666731116000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.actamedicaportuguesa.com\/revista\/index.php\/amp\/article\/view\/7812"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,3,31]]},"references-count":0,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2017,3,31]]}},"URL":"https:\/\/doi.org\/10.20344\/amp.7812","relation":{},"ISSN":["1646-0758","0870-399X"],"issn-type":[{"value":"1646-0758","type":"electronic"},{"value":"0870-399X","type":"print"}],"subject":[],"published":{"date-parts":[[2017,3,31]]}}}