{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,12]],"date-time":"2024-07-12T15:55:28Z","timestamp":1720799728031},"reference-count":0,"publisher":"Ordem dos Medicos","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Med Port"],"abstract":"<jats:p>Hemangiomas are usually diagnosed based on ultrasound findings. The presence of symptoms, rapid growth or atipical imagiological\u00a0findings should make us consider other diagnoses, including malignant tumors such as angiosarcomas. We describe the case of a\u00a0previously healthy 46-year-old female without a history of exposure to carcinogens who presented with abdominal pain for two months.\u00a0Diagnostic work-up revealed elevated gamma-glutamyl transferase and lactate dehydrogenase levels. Abdominal ultrasound described\u00a0a large nodular lesion in the right lobe of the liver described as a hemangioma. One month later, a computed tomography-scan was\u00a0made and revealed the same lesion, which had grown from 13.5 to 20 cm, maintaining typical imaging characteristics of a hemangioma.\u00a0A right hepatectomy was performed and pathology revealed an angiosarcoma. After surgery, a positron emission tomography-computed\u00a0tomography scan showed hepatic and bone metastasis. The patient started taxane-based chemotherapy and lumbar palliative\u00a0radiotherapy, but died 10 months after surgery. This case shows how difficult it is to diagnose hepatic angiosarcoma relying only on\u00a0imaging findings. Two abdominal computed tomography -scans were performed and none suggested this diagnosis. Angiosarcoma is\u00a0a very aggressive tumour with an adverse prognosis. Surgery is the only curative treatment available. However, it is rarely feasible due\u00a0to unresectable disease or distant metastasis.<\/jats:p>","DOI":"10.20344\/amp.8593","type":"journal-article","created":{"date-parts":[[2017,10,31]],"date-time":"2017-10-31T18:08:50Z","timestamp":1509473330000},"page":"750-753","source":"Crossref","is-referenced-by-count":3,"title":["Hepatic Angiosarcoma Masquerading as Hemangioma: A Challenging Differential Diagnosis"],"prefix":"10.20344","volume":"30","author":[{"given":"Ana Rita","family":"Garcia","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jo\u00e3o","family":"Ribeiro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helena","family":"Gerv\u00e1sio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco Castro e","family":"Sousa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"8464","published-online":{"date-parts":[[2017,10,31]]},"container-title":["Acta M\u00e9dica Portuguesa"],"original-title":[],"link":[{"URL":"https:\/\/www.actamedicaportuguesa.com\/revista\/index.php\/amp\/article\/download\/8593\/5209","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.actamedicaportuguesa.com\/revista\/index.php\/amp\/article\/download\/8593\/5209","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,10,25]],"date-time":"2022-10-25T08:43:02Z","timestamp":1666687382000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.actamedicaportuguesa.com\/revista\/index.php\/amp\/article\/view\/8593"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10,31]]},"references-count":0,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2017,10,31]]}},"URL":"https:\/\/doi.org\/10.20344\/amp.8593","relation":{},"ISSN":["1646-0758","0870-399X"],"issn-type":[{"value":"1646-0758","type":"electronic"},{"value":"0870-399X","type":"print"}],"subject":[],"published":{"date-parts":[[2017,10,31]]}}}