{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T05:28:44Z","timestamp":1709270924391},"reference-count":0,"publisher":"Ordem dos Medicos","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Med Port"],"abstract":"<jats:p>A mononucleose infeciosa \u00e9 uma das principais manifesta\u00e7\u00f5es cl\u00ednicas da infe\u00e7\u00e3o pelo v\u00edrus Epstein-Barr. Nesta s\u00edndrome, a eleva\u00e7\u00e3o das aminotransferases \u00e9 comum mas a colestase \u00e9 rara, havendo poucos casos descritos na literatura. Adolescente, 14 anos, sexo feminino, admitida no servi\u00e7o de urg\u00eancia por febre, odinofagia e adenomeg\u00e1lia cervical. Iniciou tratamento com amoxicilina e dois dias depois iniciou icter\u00edcia. A avalia\u00e7\u00e3o anal\u00edtica foi compat\u00edvel com hepatite colest\u00e1tica e a ecografia abdominal revelou hepatoesplenomeg\u00e1lia, sem dilata\u00e7\u00e3o das vias bilares. O diagn\u00f3stico de infe\u00e7\u00e3o pelo v\u00edrus Epstein-Barr foi confirmado pela presen\u00e7a de marcadores serol\u00f3gicos. Este caso pretende alertar para uma manifesta\u00e7\u00e3o rara de um agente infecioso comum e, consequentemente, para a inclus\u00e3o da infe\u00e7\u00e3o aguda a v\u00edrus Epstein-Barr no diagn\u00f3stico diferencial de hepatite colest\u00e1tica na idade pedi\u00e1trica.<\/jats:p>","DOI":"10.20344\/amp.8715","type":"journal-article","created":{"date-parts":[[2018,7,18]],"date-time":"2018-07-18T12:26:20Z","timestamp":1531916780000},"page":"886-888","source":"Crossref","is-referenced-by-count":1,"title":["Mononucleose Infeciosa e Hepatite Colest\u00e1tica: Uma Associa\u00e7\u00e3o Rara"],"prefix":"10.20344","volume":"30","author":[{"given":"Catarina","family":"Salgado","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Margarida","family":"Garcia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catarina","family":"R\u00fabio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Florbela","family":"Cunha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"8464","published-online":{"date-parts":[[2017,12,29]]},"container-title":["Acta M\u00e9dica Portuguesa"],"original-title":[],"link":[{"URL":"https:\/\/www.actamedicaportuguesa.com\/revista\/index.php\/amp\/article\/download\/8715\/5277","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.actamedicaportuguesa.com\/revista\/index.php\/amp\/article\/download\/8715\/5277","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,10,25]],"date-time":"2022-10-25T20:28:46Z","timestamp":1666729726000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.actamedicaportuguesa.com\/revista\/index.php\/amp\/article\/view\/8715"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,12,29]]},"references-count":0,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2017,12,29]]}},"URL":"https:\/\/doi.org\/10.20344\/amp.8715","relation":{},"ISSN":["1646-0758","0870-399X"],"issn-type":[{"value":"1646-0758","type":"electronic"},{"value":"0870-399X","type":"print"}],"subject":[],"published":{"date-parts":[[2017,12,29]]}}}