{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T04:10:26Z","timestamp":1778127026608,"version":"3.51.4"},"reference-count":0,"publisher":"Case Western Reserve University","issue":"1","license":[{"start":{"date-parts":[[2020,5,2]],"date-time":"2020-05-02T00:00:00Z","timestamp":1588377600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["PAI"],"abstract":"<jats:p>Background-Shortages of personal protective equipment (PPE) including N95 filtering facepiece respirators is an urgent concern in the setting of the global COVID-19 pandemic.\u00a0 Decontamination of PPE could be useful to maintain adequate supplies, but there is uncertainty regarding the efficacy of decontamination technologies.Methods-A modification of the American Society for Testing and Materials standard quantitative carrier disk test method (ASTM E-2197-11) was used to examine the effectiveness of ultraviolet-C (UV-C) light, a high-level disinfection cabinet that generates aerosolized peracetic acid and hydrogen peroxide, and dry heat at 70\u00b0C for 30 minutes for decontamination of bacteriophages Phi6 and MS2 and methicillin-resistant Staphylococcus aureus (MRSA) inoculated onto 3 commercial N95 respirators.\u00a0 Three and 6 log10 reductions on N95 respirators were considered effective for decontamination and disinfection, respectively.\u00a0Results-UV-C administered as a 1-minute cycle in a UV-C box or a 30-minute cycle by a room decontamination device reduced contamination but did not meet criteria for decontamination of the viruses from all sites for any of the N95s.\u00a0 The high-level disinfection cabinet was effective for decontamination of all the organisms from the N95s and achieved disinfection with 3 disinfection cycles over ~60 minutes.\u00a0 Dry heat at 70\u00b0C for 30 minutes was not effective for decontamination of the bacteriophages.\u00a0\u00a0Conclusions-UV-C could be useful to reduce contamination on N95 respirators.\u00a0 However, the UV-C technologies studied did not meet our criteria for decontamination under the test conditions used.\u00a0 The high-level disinfection cabinet was effective for decontamination of N95s and met criteria for disinfection with multiple cycles.<\/jats:p>","DOI":"10.20411\/pai.v5i1.372","type":"journal-article","created":{"date-parts":[[2020,5,5]],"date-time":"2020-05-05T18:11:22Z","timestamp":1588702282000},"page":"52","source":"Crossref","is-referenced-by-count":92,"title":["Effectiveness of Ultraviolet-C Light and a High-Level Disinfection Cabinet for Decontamination of N95 Respirators"],"prefix":"10.20411","volume":"5","author":[{"given":"Jennifer L.","family":"Cadnum","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah N.","family":"Redmond","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amrita R.","family":"John","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Basya","family":"Pearlmutter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0990-4498","authenticated-orcid":false,"given":"Curtis","family":"Donskey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7530","published-online":{"date-parts":[[2020,5,2]]},"container-title":["Pathogens and Immunity"],"original-title":[],"link":[{"URL":"https:\/\/paijournal.com\/index.php\/paijournal\/article\/viewFile\/372\/249","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/paijournal.com\/index.php\/paijournal\/article\/viewFile\/372\/248","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/paijournal.com\/index.php\/paijournal\/article\/viewFile\/372\/248","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,8,31]],"date-time":"2020-08-31T03:34:36Z","timestamp":1598844876000},"score":1,"resource":{"primary":{"URL":"https:\/\/paijournal.com\/index.php\/paijournal\/article\/view\/372"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5,2]]},"references-count":0,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2020,1,20]]}},"URL":"https:\/\/doi.org\/10.20411\/pai.v5i1.372","relation":{},"ISSN":["2469-2964"],"issn-type":[{"value":"2469-2964","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,5,2]]}}}