{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T02:12:47Z","timestamp":1783649567328,"version":"3.55.0"},"reference-count":36,"publisher":"Korea Society for Exercise Nutrition","issue":"2","license":[{"start":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T00:00:00Z","timestamp":1782777600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/2.0\/"}],"funder":[{"DOI":"10.13039\/501100002701","name":"Ministry of Education","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002701","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["2021S1A5A8069363"],"award-info":[{"award-number":["2021S1A5A8069363"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002628","name":"Incheon National University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002628","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["e-pan.org"],"crossmark-restriction":true},"short-container-title":["Phys Act Nutr"],"published-print":{"date-parts":[[2026,6,30]]},"abstract":"<jats:p>[Purpose] This narrative review synthesizes magnetic resonance imaging (MRI) evidence of (i) the associations between physical activity and\/or aerobic fitness and brain markers related to cognitive function in Parkinson\u2019s disease (PD); and (ii) MRI-derived brain markers linked to gait impairment in PD. We also propose a conceptual framework describing how physical activity or fitness may support the cognitive-motor networks associated with gait.[Methods] PubMed and Web of Science were searched for MRI studies examining the relationships between physical activity\/fitness and cognition-relevant brain markers as well as MRI studies linking brain markers to gait outcomes (including cognition-related gait measures and freezing of gait).[Results] Fourteen observational studies met our inclusion criteria. Higher physical activity and\/or fitness were seen to be generally associated with better cognitive performance and MRI features suggestive of preserved brain integrity and connectivity within the cognitive-motor networks. Regarding gait, the reviewed evidence suggests a shift toward greater reliance on cognitive-motor control to compensate for impaired automatic motor control, which may occur when this compensatory cognitive control becomes insufficient under increased task demands.[Conclusion] Physical activity and fitness may contribute to gait function in patients with Parkinson\u2019s disease by supporting the cognitive-motor integration required for walking. Longitudinal and interventional studies using ecologically valid paradigms that approximate real-world (including dual-task) walking, ideally combined with wearable neuroimaging approaches, are needed to clarify how changes in physical activity or fitness are related to neural markers of gait.<\/jats:p>","DOI":"10.20463\/pan.2026.0014","type":"journal-article","created":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T06:22:32Z","timestamp":1782800552000},"page":"7-13","update-policy":"https:\/\/doi.org\/10.20463\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Brain markers of cognitive-motor control of gait function in Parkinson\u2019s disease: links with physical activity and aerobic fitness"],"prefix":"10.20463","volume":"30","author":[{"given":"Heehyun","family":"Shin","sequence":"first","affiliation":[{"name":"Department of Human Movement Science, Incheon National University, Incheon, Republic of 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