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This was accompanied by decreased occurrence of Akkermansia muciniphila  and Enterococcus faecalis , but results did not reach statistical significance in all groups depending on diet and inter-individual differences. Changes in host parameters (anthropometry, blood glucose, and cholesterol) and liver proteomes were primarily due to diet. In contrast, metabolomes in colon content differed significantly between the colonisation groups. The presence of E. lenta   was associated with elevated levels of latifolicinin C acid and decreased creatine, sarcosine, N,N-dimethylarginine,  and N-Acetyl-DL-methionine. In conclusion, E. lenta  altered specific metabolites in the colon but did not have significant effects on the mice or liver proteomes under the conditions tested due to marked inter-individual differences.<\/jats:p>","DOI":"10.20517\/mrr.2023.65","type":"journal-article","created":{"date-parts":[[2024,1,18]],"date-time":"2024-01-18T01:00:25Z","timestamp":1705539625000},"update-policy":"https:\/\/doi.org\/10.20517\/oae.crossmark.policy","source":"Crossref","is-referenced-by-count":6,"title":["The human intestinal bacterium\n                    <i>Eggerthella lenta<\/i>\n                    influences gut metabolomes in gnotobiotic 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