{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T05:24:53Z","timestamp":1740115493834,"version":"3.37.3"},"reference-count":0,"publisher":"Socidrogalcohol","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Adicciones"],"abstract":"<jats:p>The objective was to evaluate outcomes in a heroin-dependent population 35 years after first enrolment in methadone maintenance treatment (MMT).\u00a0 An ad hoc protocol was used to assess drug misuse, treatment, and drug-related morbidity in the survivor sample. The standardized mortality ratio (SMR) and 95% confidence interval (CI) were calculated.\u00a0 A total of 214 heroin-dependent patients entered MMT between 1982 and 1984 in the Asturias Public Health Service. Information was received on 195 subjects, of whom 146 were deceased.\u00a0 Men accounted for 77.5% of the study cohort. Over the 35-year follow-up period, the SMR was 11.75 (95% CI = 9.95 \u2013 13.77). In the survivor sample, 5.7% were still enrolled in MMT; human immunodeficiency virus (HIV) was diagnosed in 38.77% and hepatitis B\/C in 73.46%. No differences were found between sexes in mortality or HIV and hepatitis B\/C status. None of the female survivors were using heroin at the 35-year follow-up compared with 5.26% of males. In conclusion, our study confirms the high long-term mortality rate of heroin addicts, even after enrollment in MMT.\u00a0<\/jats:p>","DOI":"10.20882\/adicciones.1662","type":"journal-article","created":{"date-parts":[[2021,11,24]],"date-time":"2021-11-24T11:17:37Z","timestamp":1637752657000},"page":"303-314","source":"Crossref","is-referenced-by-count":0,"title":["A 35-year follow-up study of patients admitted to methadone treatment between 1982-1984 in Asturias, Spain"],"prefix":"10.20882","volume":"35","author":[{"given":"Luis","family":"Jim\u00e9nez-Trevi\u00f1o","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Clara","family":"Mart\u00ednez-Cao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernando","family":"S\u00e1nchez-Lasheras","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Celso","family":"Iglesias","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda Jes\u00fas","family":"Antu\u00f1a","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leonor","family":"Riera","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pilar Alejandra","family":"S\u00e1iz-Mart\u00ednez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julio","family":"Bobes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"8502","published-online":{"date-parts":[[2021,11,23]]},"container-title":["Adicciones"],"original-title":[],"link":[{"URL":"https:\/\/adicciones.es\/index.php\/adicciones\/article\/download\/1662\/1286","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/adicciones.es\/index.php\/adicciones\/article\/download\/1662\/1286","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,20]],"date-time":"2025-02-20T12:01:02Z","timestamp":1740052862000},"score":1,"resource":{"primary":{"URL":"https:\/\/adicciones.es\/index.php\/adicciones\/article\/view\/1662"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,23]]},"references-count":0,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2023,9,29]]}},"URL":"https:\/\/doi.org\/10.20882\/adicciones.1662","relation":{},"ISSN":["0214-4840"],"issn-type":[{"type":"print","value":"0214-4840"}],"subject":[],"published":{"date-parts":[[2021,11,23]]}}}