{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,20]],"date-time":"2025-02-20T12:40:37Z","timestamp":1740055237313,"version":"3.37.3"},"reference-count":0,"publisher":"Socidrogalcohol","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Adicciones"],"abstract":"<jats:p>El da\u00f1o cerebral relacionado con el consumo de alcohol se asocia a alteraciones de las funciones cognitivas, entre las que destacan memoria y aprendizaje verbal. El objetivo principal es evaluar memoria y aprendizaje verbal en una muestra de 111 pacientes con trastorno por consumo de alcohol (TCA) versus 78 con trastorno de depresi\u00f3n mayor (TDM) y 100 controles sanos. La evaluaci\u00f3n incluy\u00f3 variables sociodemogr\u00e1ficas y cl\u00ednicas, la Escala de Hamilton para la Depresi\u00f3n (HDRS) y el Test de Aprendizaje Verbal de California (CVLT). Se utiliz\u00f3 ANOVA de un factor para comparaciones entre los 3 grupos y ANCOVAS bidireccionales incluyendo diferentes covariables. El ANOVA de un factor muestra que los pacientes con TCA y TDM obtienen puntuaciones similares entre s\u00ed e inferiores a las del grupo control (p &lt; 0,001), con excepci\u00f3n del CVLT Guiado (peores puntuaciones en TDM vs TCA, p &lt; 0,001). Tras incluir como covariables la edad, sexo y los a\u00f1os de estudios completados, persisten las diferencias entre los grupos de TCA y TDM frente al grupo control (p \u2264 0,003) en todos los \u00edndices con excepci\u00f3n del CVLT Libre Inmediato y del CVLT Guiado (peor rendimiento en TDM vs TCA, p = 0,022 y p = 0,035, respectivamente). En el segundo ANCOVA, tras controlar por gravedad de la depresi\u00f3n, \u00fanicamente se detectan diferencias entre los pacientes con TCA y los controles sanos (p \u2264 0,007). Los pacientes con TCA presentan una importante alteraci\u00f3n en aprendizaje y memoria verbal al compararlos con pacientes con TDM y con personas sanas.\u00a0<\/jats:p>","DOI":"10.20882\/adicciones.1696","type":"journal-article","created":{"date-parts":[[2021,11,24]],"date-time":"2021-11-24T11:17:37Z","timestamp":1637752657000},"page":"21-30","source":"Crossref","is-referenced-by-count":0,"title":["Aprendizaje y memoria verbal: Comparaci\u00f3n entre pacientes con trastorno por consumo de alcohol y trastorno de depresi\u00f3n mayor"],"prefix":"10.20882","volume":"36","author":[{"given":"Rocio","family":"Villa Diez","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julia","family":"Rodr\u00edguez-Revuelta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashkan","family":"Espandian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabel","family":"Men\u00e9ndez-Miranda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Dal Santo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda Paz","family":"Garc\u00eda-Portilla","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerardo","family":"Fl\u00f3rez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julio","family":"Bobes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pilar Alejandra","family":"S\u00e1iz Mart\u00ednez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"8502","published-online":{"date-parts":[[2021,11,24]]},"container-title":["Adicciones"],"original-title":[],"link":[{"URL":"https:\/\/adicciones.es\/index.php\/adicciones\/article\/download\/1696\/1296","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/adicciones.es\/index.php\/adicciones\/article\/download\/1696\/1295","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,20]],"date-time":"2025-02-20T12:00:17Z","timestamp":1740052817000},"score":1,"resource":{"primary":{"URL":"https:\/\/adicciones.es\/index.php\/adicciones\/article\/view\/1696"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,24]]},"references-count":0,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,3,30]]}},"URL":"https:\/\/doi.org\/10.20882\/adicciones.1696","relation":{},"ISSN":["0214-4840"],"issn-type":[{"type":"print","value":"0214-4840"}],"subject":[],"published":{"date-parts":[[2021,11,24]]}}}