{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T03:30:42Z","timestamp":1787023842443,"version":"build-2736575974"},"reference-count":0,"publisher":"Socidrogalcohol","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Adicciones"],"abstract":"<jats:p>El manejo del trastorno por consumo de alcohol (TCA) resistente al tratamiento presenta desaf\u00edos. La terapia de exposici\u00f3n a se\u00f1ales con realidad virtual (TES-RV) es un enfoque complementario al tratamiento est\u00e1ndar (TE). Este ensayo cl\u00ednico aleatorizado (ECA) evalu\u00f3 la eficacia de TES-RV con TE, comparado con TE solo, para reducir craving y ansiedad por el alcohol en pacientes con TCA resistente. Tambi\u00e9n busc\u00f3 determinar niveles de craving y ansiedad durante las sesiones de TES-RV y explorar efectos a largo plazo en la abstinencia. Participaron 85 pacientes con TCA del Hospital Cl\u00ednic de Barcelona. Fueron asignados aleatoriamente a un grupo experimental (GE), con TES-RV m\u00e1s TE, o a un grupo control (GC), solo con TE. El GE complet\u00f3 seis sesiones de TES-RV junto con TE; el GC continu\u00f3 solo con TE. Se evaluaron craving y ansiedad por el alcohol antes y despu\u00e9s del tratamiento en ambos grupos, y durante las sesiones de TES-RV en el GE. Las reca\u00eddas se monitorizaron a los 3, 6 y 12 meses post-tratamiento. Los resultados no mostraron efectos significativos del tipo de tratamiento (GE vs. GC) sobre craving ni ansiedad. No obstante, un factor temporal significativo indic\u00f3 reducciones en craving y ansiedad del pretest al postest, independientemente del tratamiento. Durante las sesiones de TES-RV, los participantes del GE reportaron niveles m\u00ednimos de craving y ansiedad al finalizar. No se hallaron diferencias estad\u00edsticamente significativas en las tasas de reca\u00edda entre el GE y el GC en ning\u00fan seguimiento. El estudio discute implicaciones cl\u00ednicas, limitaciones y futuras l\u00edneas de investigaci\u00f3n.<\/jats:p>","DOI":"10.20882\/adicciones.1958","type":"journal-article","created":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T13:55:01Z","timestamp":1758549301000},"page":"199-216","source":"Crossref","is-referenced-by-count":2,"title":["Proyecto ALCO-VR: Un ensayo cl\u00ednico aleatorizado para la evaluaci\u00f3n de la eficacia de la Terapia de Exposici\u00f3n a Se\u00f1ales con Realidad Virtual en pacientes resistentes al tratamiento diagnosticados con trastorno por uso de alcohol"],"prefix":"10.20882","volume":"37","author":[{"given":"Alexandra","family":"Ghi\u0163\u0103","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olga","family":"Hern\u00e1ndez-Serrano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jolanda","family":"Fern\u00e1ndez-Ruiz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariano","family":"Gacto-S\u00e1nchez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miquel","family":"Monras","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antoni","family":"Gual","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno","family":"Porras-Garc\u00eda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"Ferrer-Garc\u00eda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9","family":"Guti\u00e9rrez-Maldonado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"8502","published-online":{"date-parts":[[2025,9,22]]},"container-title":["Adicciones"],"original-title":[],"link":[{"URL":"https:\/\/adicciones.es\/index.php\/adicciones\/article\/download\/1958\/1629","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/adicciones.es\/index.php\/adicciones\/article\/download\/1958\/1628","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T14:29:07Z","timestamp":1759156147000},"score":1,"resource":{"primary":{"URL":"https:\/\/adicciones.es\/index.php\/adicciones\/article\/view\/1958"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,22]]},"references-count":0,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2025,9,22]]}},"URL":"https:\/\/doi.org\/10.20882\/adicciones.1958","relation":{},"ISSN":["0214-4840"],"issn-type":[{"value":"0214-4840","type":"print"}],"subject":[],"published":{"date-parts":[[2025,9,22]]}}}