{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T21:02:35Z","timestamp":1760043755978,"version":"3.37.3"},"reference-count":0,"publisher":"Socidrogalcohol","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Adicciones"],"abstract":"<jats:p>Las personas con esquizofrenia constituyen una parte sustancial de las personas que todav\u00eda fuman. La hip\u00f3tesis de la automedicaci\u00f3n en relaci\u00f3n al rendimiento cognitivo mantiene que los pacientes fuman para mejorar su d\u00e9ficit cognitivo bas\u00e1ndose en los efectos estimulantes de la nicotina. El objetivo de este art\u00edculo es describir la metodolog\u00eda del estudio COGNICO. Estudio cuasiexperimental, observacional, prospectivo, multic\u00e9ntrico y\u00a0 con seguimiento a 3, 6, 12 y 18 meses. Fue llevado a cabo en tres ciudades del norte de Espa\u00f1a (Oviedo, Ourense y Santiago de Compostela). Se reclutaron 81pacientes con esquizofrenia fumadores (edad media de 43,35 a\u00f1os (DT=8,83). 72,8% varones). Se asignaron a 3 grupos: a) control: pacientes fumadores; b) pacientes que dejan de fumar mediante parches de nicotina; c) pacientes que dejan de fumar mediante vareniclina. Como medida primaria se aplic\u00f3 la bater\u00eda neuropsicol\u00f3gica MATRICS. Adem\u00e1s, se llev\u00f3 a cabo una evaluaci\u00f3n comprehensiva de los pacientes, que inclu\u00eda\u00a0 el n\u00famero de cigarrillos por d\u00eda, la dependencia f\u00edsica y psicol\u00f3gica a la nicotina y el CO expirado. Tambi\u00e9n se realiz\u00f3 una evaluaci\u00f3n cl\u00ednica general (PANSS, HDRS, ICG, C-SSRS) as\u00ed como un seguimiento de las medidas antropom\u00e9tricas y los signos vitales. Se pretende\u00a0 identificar la relaci\u00f3n entre el patr\u00f3n de consumo de tabaco y el rendimiento cognitivo mediante la comparaci\u00f3n de las puntuaciones en la bater\u00eda neuropsicol\u00f3gica MATRICS durante los per\u00edodos de seguimiento.<\/jats:p>","DOI":"10.20882\/adicciones.724","type":"journal-article","created":{"date-parts":[[2016,6,22]],"date-time":"2016-06-22T17:01:26Z","timestamp":1466614886000},"page":"6-12","source":"Crossref","is-referenced-by-count":2,"title":["Tabaco y rendimiento cognitivo en pacientes con esquizofrenia: dise\u00f1o del estudio COGNICO"],"prefix":"10.20882","volume":"29","author":[{"given":"Susana","family":"Al-Halab\u00ed","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sergio","family":"Fern\u00e1ndez-Artamendi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eva M.","family":"D\u00edaz-Mesa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leticia","family":"Garc\u00eda-\u00c1lvarez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerardo","family":"Fl\u00f3rez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emilia","family":"Mart\u00ednez-Santamar\u00eda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manuel","family":"Arrojo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pilar A.","family":"Saiz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. Paz","family":"Garc\u00eda-Portilla","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julio","family":"Bobes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"8502","published-online":{"date-parts":[[2016,6,14]]},"container-title":["Adicciones"],"original-title":[],"link":[{"URL":"https:\/\/adicciones.es\/index.php\/adicciones\/article\/download\/724\/767","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/adicciones.es\/index.php\/adicciones\/article\/download\/724\/766","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,20]],"date-time":"2025-02-20T12:27:40Z","timestamp":1740054460000},"score":1,"resource":{"primary":{"URL":"https:\/\/adicciones.es\/index.php\/adicciones\/article\/view\/724"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,6,14]]},"references-count":0,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2017,1,12]]}},"URL":"https:\/\/doi.org\/10.20882\/adicciones.724","relation":{},"ISSN":["0214-4840"],"issn-type":[{"type":"print","value":"0214-4840"}],"subject":[],"published":{"date-parts":[[2016,6,14]]}}}