{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,6]],"date-time":"2025-06-06T13:29:36Z","timestamp":1749216576817,"version":"3.40.5"},"reference-count":64,"publisher":"Archives of Endocrinology and Metabolism","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,10,21]]},"DOI":"10.20945\/2359-3997000000301","type":"journal-article","created":{"date-parts":[[2020,11,19]],"date-time":"2020-11-19T16:44:37Z","timestamp":1605804277000},"source":"Crossref","is-referenced-by-count":3,"title":["Prevention and treatment of oral adverse effects of antiresorptive medications for osteoporosis \u2013 A position paper of the Brazilian Society of Endocrinology and Metabolism (SBEM), Brazilian Society of Stomatology and Oral Pathology (Sobep), and Brazilian Association for Bone Evaluation and Osteometabolism (Abrasso)"],"prefix":"10.20945","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6752-2880","authenticated-orcid":false,"given":"Miguel","family":"Madeira","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0070-0640","authenticated-orcid":false,"given":"Andr\u00e9 Caroli","family":"Rocha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9908-4907","authenticated-orcid":false,"given":"Carolina Aguiar","family":"Moreira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9666-9272","authenticated-orcid":false,"given":"\u00c1guida Maria Menezes","family":"Aguiar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2669-4245","authenticated-orcid":false,"given":"Sergio Setsuo","family":"Maeda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9771-3960","authenticated-orcid":false,"given":"Abel Silveira","family":"Cardoso","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9144-996X","authenticated-orcid":false,"given":"Charlles Heldan de Moura","family":"Castro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7332-9841","authenticated-orcid":false,"given":"Catarina Brasil","family":"D'Alva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7276-581X","authenticated-orcid":false,"given":"Barbara Campolina Carvalho","family":"Silva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4863-2544","authenticated-orcid":false,"given":"Bruno","family":"Ferraz-de-Souza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9186-2834","authenticated-orcid":false,"given":"Marise","family":"Lazaretti-Castro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0290-0742","authenticated-orcid":false,"given":"Francisco","family":"Bandeira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9271-3707","authenticated-orcid":false,"given":"Sandra R.","family":"Torres","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"8510","reference":[{"issue":"5","key":"key20201119114411_B1","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1016\/j.joms.2009.10.010","article-title":"Osteonecrosis of the jaw in a patient on Denosumab","volume":"68","author":"Aghaloo","year":"2010","unstructured":"1. Aghaloo TL, Felsenfeld AL, Tetradis S. Osteonecrosis of the jaw in a patient on Denosumab. J Oral Maxillofac Surg. 2010;68(5):959-63.","journal-title":"J Oral Maxillofac Surg"},{"issue":"24","key":"key20201119114411_B2","doi-asserted-by":"crossref","first-page":"4037","DOI":"10.1200\/JCO.2007.15.5424","article-title":"Osteonecrosis of the jaw related to bevacizumab","volume":"26","author":"Estilo","year":"2008","unstructured":"2. Estilo CL, Fornier M, Farooki A, Carlson D, Bohle G 3rd, Huryn JM. Osteonecrosis of the jaw related to bevacizumab. J Clin Oncol. 2008;26(24):4037-8.","journal-title":"J Clin Oncol"},{"issue":"Suppl 2","key":"key20201119114411_B3","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1016\/j.rbr.2017.06.001","article-title":"Brazilian guidelines for the diagnosis and treatment of postmenopausal osteoporosis","volume":"57","author":"Radominski","year":"2017","unstructured":"3. Radominski SC, Bernardo W, Paula AP, Albergaria BH, Moreira C, Fernandes CE, et al. Brazilian guidelines for the diagnosis and treatment of postmenopausal osteoporosis. Rev Bras Reumatol. 2017;57(Suppl 2):452-66.","journal-title":"Rev Bras Reumatol"},{"issue":"5","key":"key20201119114411_B4","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/j.joms.2004.02.004","article-title":"Osteonecrosis of the jaws associated with the use of bisphosphonates: a review of 63 cases","volume":"62","author":"Ruggiero","year":"2004","unstructured":"4. Ruggiero SL, Mehrotra B, Rosenberg TJ, Engroff SL. Osteonecrosis of the jaws associated with the use of bisphosphonates: a review of 63 cases. J Oral Maxillofac Surg. 2004;62(5):527-34.","journal-title":"J Oral Maxillofac Surg"},{"issue":"9","key":"key20201119114411_B5","doi-asserted-by":"crossref","first-page":"1032","DOI":"10.4065\/83.9.1032","article-title":"Bisphosphonates: mechanism of action and role in clinical practice","volume":"83","author":"Drake","year":"2008","unstructured":"5. Drake MT, Clarke BL, Khosla S. Bisphosphonates: mechanism of action and role in clinical practice. Mayo Clin Proc. 2008;83(9):1032-45.","journal-title":"Mayo Clin Proc"},{"issue":"3","key":"key20201119114411_B6","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1007\/s00198-008-0680-5","article-title":"Clinical risk factors for osteoporotic fractures in Brazilian women and men: the Brazilian Osteoporosis Study (BRAZOS)","volume":"20","author":"Pinheiro","year":"2009","unstructured":"6. Pinheiro MM, Ciconelli RM, Martini LA, Ferraz MB. Clinical risk factors for osteoporotic fractures in Brazilian women and men: the Brazilian Osteoporosis Study (BRAZOS). Osteoporos Int. 2009;20(3):399-408.","journal-title":"Osteoporos Int"},{"issue":"7","key":"key20201119114411_B7","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1080\/13696998.2019.1590843","article-title":"The burden of osteoporosis in four Latin American countries: Brazil, Mexico, Colombia, and Argentina","volume":"22","author":"Aziziyeh","year":"2019","unstructured":"7. Aziziyeh R, Amin M, Habib M, Garcia Perlaza J, Szafranski K, McTavish RK, et al. The burden of osteoporosis in four Latin American countries: Brazil, Mexico, Colombia, and Argentina. J Med Econ. 2019;22(7):638-44.","journal-title":"J Med Econ"},{"issue":"10","key":"key20201119114411_B8","doi-asserted-by":"crossref","first-page":"1938","DOI":"10.1016\/j.joms.2014.04.031","article-title":"American Association of Oral and Maxillofacial Surgeons position paper on medication-related osteonecrosis of the jaw \u2013 2014 update","volume":"72","author":"Ruggiero","year":"2014","unstructured":"8. Ruggiero SL, Dodson TB, Fantasia J, Goodday R, Aghaloo T, Mehrotra B, et al. American Association of Oral and Maxillofacial Surgeons position paper on medication-related osteonecrosis of the jaw \u2013 2014 update. J Oral Maxillofac Surg. 2014;72(10):1938-56.","journal-title":"J Oral Maxillofac Surg"},{"issue":"2","key":"key20201119114411_B9","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1590\/0004-2730000003039","article-title":"An overview on the treatment of postmenopausal osteoporosis","volume":"58","author":"Maeda","year":"2014","unstructured":"9. Maeda SS, Lazaretti-Castro M. An overview on the treatment of postmenopausal osteoporosis. Arq Bras Endocrinol Metabol. 2014;58(2):162-71.","journal-title":"Arq Bras Endocrinol Metabol"},{"issue":"9","key":"key20201119114411_B10","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1016\/S0278-2391(03)00720-1","article-title":"Pamidronate (Aredia) and zoledronate (Zometa) induced avascular necrosis of the jaws: a growing epidemic","volume":"61","author":"Marx","year":"2003","unstructured":"10. Marx RE. Pamidronate (Aredia) and zoledronate (Zometa) induced avascular necrosis of the jaws: a growing epidemic. J Oral Maxillofac Surg. 2003;61(9):1115-7.","journal-title":"J Oral Maxillofac Surg"},{"issue":"3","key":"key20201119114411_B11","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.1210\/jc.2004-0952","article-title":"Severely suppressed bone turnover: a potential complication of alendronate therapy","volume":"90","author":"Odvina","year":"2005","unstructured":"11. Odvina CV, Zerwekh JE, Rao DS, Maalouf N, Gottschalk FA, Pak CY. Severely suppressed bone turnover: a potential complication of alendronate therapy. J Clin Endocrinol Metab. 2005;90(3):1294-301.","journal-title":"J Clin Endocrinol Metab"},{"issue":"9","key":"key20201119114411_B12","doi-asserted-by":"crossref","first-page":"619","DOI":"10.3949\/ccjm.78a.11022","article-title":"What is the optimal duration of bisphosphonate therapy?","volume":"78","author":"Ott","year":"2011","unstructured":"12. Ott SM. What is the optimal duration of bisphosphonate therapy? Cleve Clin J Med. 2011;78(9):619-30.","journal-title":"Cleve Clin J Med"},{"issue":"7","key":"key20201119114411_B13","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1016\/S2213-8587(17)30138-9","article-title":"10 years of denosumab treatment in postmenopausal women with osteoporosis: results from the phase 3 randomised randomized FREEDOM trial and open-label extension","volume":"5","author":"Bone","year":"2017","unstructured":"13. Bone HG, Wagman RB, Brandi ML, Brown JP, Chapurlat R, Cummings SR, et al. 10 years of denosumab treatment in postmenopausal women with osteoporosis: results from the phase 3 randomised randomized FREEDOM trial and open-label extension. Lancet Diabetes Endocrinol. 2017;5(7):513-23.","journal-title":"Lancet Diabetes Endocrinol"},{"key":"key20201119114411_B14","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.bone.2017.08.003","article-title":"Discontinuation of Denosumab therapy for osteoporosis: A systematic review and position statement by ECTS","volume":"105","author":"Tsourdi","year":"2017","unstructured":"14. Tsourdi E, Langdahl B, Cohen-Solal M, Aubry-Rozier B, Eriksen EF, Guanabens N, et al. Discontinuation of Denosumab therapy for osteoporosis: A systematic review and position statement by ECTS. Bone. 2017;105:11-7.","journal-title":"Bone"},{"issue":"1","key":"key20201119114411_B15","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1002\/jbmr.2405","article-title":"Diagnosis and management of osteonecrosis of the jaw: a systematic review and international consensus","volume":"30","author":"Khan","year":"2015","unstructured":"15. Khan AA, Morrison A, Hanley DA, Felsenberg D, McCauley LK, O'Ryan F, et al. Diagnosis and management of osteonecrosis of the jaw: a systematic review and international consensus. J Bone Miner Res. 2015;30(1):3-23.","journal-title":"J Bone Miner Res"},{"issue":"1","key":"key20201119114411_B16","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1007\/s00774-016-0810-7","article-title":"Antiresorptive agent-related osteonecrosis of the jaw: Position Paper 2017 of the Japanese Allied Committee on Osteonecrosis of the Jaw","volume":"35","author":"Japanese Allied Committee on Osteonecrosis of the Jaw","year":"2017","unstructured":"16. Japanese Allied Committee on Osteonecrosis of the Jaw, Yoneda T, Hagino H, Sugimoto T, Ohta H, Takahashi S, Soen S, et al. Antiresorptive agent-related osteonecrosis of the jaw: Position Paper 2017 of the Japanese Allied Committee on Osteonecrosis of the Jaw. J Bone Miner Metab. 2017;35(1):6-19.","journal-title":"J Bone Miner Metab"},{"issue":"1","key":"key20201119114411_B17","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.jocd.2016.09.005","article-title":"Case-Based Review of Osteonecrosis of the Jaw (ONJ) and Application of the International Recommendations for Management From the International Task Force on ONJ","volume":"20","author":"Khan","year":"2017","unstructured":"17. Khan AA, Morrison A, Kendler DL, Rizzoli R, Hanley DA, Felsenberg D, et al. Case-Based Review of Osteonecrosis of the Jaw (ONJ) and Application of the International Recommendations for Management From the International Task Force on ONJ. J Clin Densitom. 2017;20(1):8-24.","journal-title":"J Clin Densitom"},{"issue":"5","key":"key20201119114411_B18","doi-asserted-by":"crossref","first-page":"2265","DOI":"10.1007\/s00520-019-05044-0","article-title":"Prevalence and risk factors of medication-related osteonecrosis of the jaw in osteoporotic and breast cancer patients: a cross-sectional study","volume":"28","author":"Soares","year":"2020","unstructured":"18. Soares AL, Simon S, Gebrim LH, Nazario ACP, Lazaretti-Castro M. Prevalence and risk factors of medication-related osteonecrosis of the jaw in osteoporotic and breast cancer patients: a cross-sectional study. Support Care Cancer. 2020;28(5):2265-71.","journal-title":"Support Care Cancer"},{"issue":"6","key":"key20201119114411_B19","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1002\/jbmr.2179","article-title":"A large case-control study reveals a positive association between bisphosphonate use and delayed dental healing and osteonecrosis of the jaw","volume":"29","author":"Borromeo","year":"2014","unstructured":"19. Borromeo GL, Brand C, Clement JG, McCullough M, Crighton L, Hepworth G, et al. A large case-control study reveals a positive association between bisphosphonate use and delayed dental healing and osteonecrosis of the jaw. J Bone Miner Res. 2014;29(6):1363-8.","journal-title":"J Bone Miner Res"},{"issue":"10","key":"key20201119114411_B20","doi-asserted-by":"crossref","first-page":"2921","DOI":"10.1007\/s00198-017-4132-y","article-title":"Surgically treated osteonecrosis and osteomyelitis of the jaw and oral cavity in patients highly adherent to alendronate treatment: a nationwide user-only cohort study including over 60,000 alendronate users","volume":"28","author":"Eiken","year":"2017","unstructured":"20. Eiken PA, Prieto-Alhambra D, Eastell R, Abrahamsen B. Surgically treated osteonecrosis and osteomyelitis of the jaw and oral cavity in patients highly adherent to alendronate treatment: a nationwide user-only cohort study including over 60,000 alendronate users. Osteoporos Int. 2017;28(10):2921-8.","journal-title":"Osteoporos Int"},{"issue":"2","key":"key20201119114411_B21","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.jebdp.2016.05.007","article-title":"Bisphosphonates, Osteoporosis, and Osteonecrosis of the Jaw: A Critical Review of a Large Nested Case-Control Study","volume":"16","author":"Zavras","year":"2016","unstructured":"21. Zavras AI, Shanmugham JR. Bisphosphonates, Osteoporosis, and Osteonecrosis of the Jaw: A Critical Review of a Large Nested Case-Control Study. J Evid Based Dent Pract. 2016;16(2):136-8.","journal-title":"J Evid Based Dent Pract"},{"issue":"1","key":"key20201119114411_B22","doi-asserted-by":"crossref","first-page":"45","DOI":"10.5624\/isd.2017.47.1.45","article-title":"Risk factors of osteonecrosis of the jaw after tooth extraction in osteoporotic patients on oral bisphosphonates","volume":"47","author":"Jeong","year":"2017","unstructured":"22. Jeong HG, Hwang JJ, Lee JH, Kim YH, Na JY, Han SS. Risk factors of osteonecrosis of the jaw after tooth extraction in osteoporotic patients on oral bisphosphonates. Imaging Sci Dent. 2017;47(1):45-50.","journal-title":"Imaging Sci Dent"},{"issue":"11","key":"key20201119114411_B23","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1016\/j.ijom.2012.06.020","article-title":"Increased incidence of osteonecrosis of the jaw after tooth extraction in patients treated with bisphosphonates: a cohort study","volume":"41","author":"Yamazaki","year":"2012","unstructured":"23. Yamazaki T, Yamori M, Ishizaki T, Asai K, Goto K, Takahashi K, et al. Increased incidence of osteonecrosis of the jaw after tooth extraction in patients treated with bisphosphonates: a cohort study. Int J Oral Maxillofac Surg. 2012;41(11):1397-403.","journal-title":"Int J Oral Maxillofac Surg"},{"issue":"7","key":"key20201119114411_B24","doi-asserted-by":"crossref","first-page":"1815","DOI":"10.1111\/odi.13160","article-title":"Workshop of European task force on medication-related osteonecrosis of the jaw-Current challenges","volume":"25","author":"Schiodt","year":"2019","unstructured":"24. Schiodt M, Otto S, Fedele S, Bedogni A, Nicolatou-Galitis O, Guggenberger R, et al. Workshop of European task force on medication-related osteonecrosis of the jaw-Current challenges. Oral Dis. 2019;25(7):1815-21.","journal-title":"Oral Dis"},{"issue":"10","key":"key20201119114411_B25","doi-asserted-by":"crossref","first-page":"922","DOI":"10.1111\/jcpe.12455","article-title":"Occurrence and risk indicators of medication-related osteonecrosis of the jaw after dental extraction: a systematic review and meta-analysis","volume":"42","author":"Gaudin","year":"2015","unstructured":"25. Gaudin E, Seidel L, Bacevic M, Rompen E, Lambert F. Occurrence and risk indicators of medication-related osteonecrosis of the jaw after dental extraction: a systematic review and meta-analysis. J Clin Periodontol. 2015;42(10):922-32.","journal-title":"J Clin Periodontol"},{"issue":"6","key":"key20201119114411_B26","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1016\/j.jcms.2015.03.039","article-title":"Tooth extraction in patients receiving oral or intravenous bisphosphonate administration: A trigger for BRONJ development?","volume":"43","author":"Otto","year":"2015","unstructured":"26. Otto S, Troltzsch M, Jambrovic V, Panya S, Probst F, Ristow O, et al. Tooth extraction in patients receiving oral or intravenous bisphosphonate administration: A trigger for BRONJ development? J Craniomaxillofac Surg. 2015;43(6):847-54.","journal-title":"J Craniomaxillofac Surg"},{"issue":"1","key":"key20201119114411_B27","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1002\/jbmr.2708","article-title":"Managing Osteoporosis in Patients on Long-Term Bisphosphonate Treatment: Report of a Task Force of the American Society for Bone and Mineral Research","volume":"31","author":"Adler","year":"2016","unstructured":"27. Adler RA, El-Hajj Fuleihan G, Bauer DC, Camacho PM, Clarke BL, Clines GA, et al. Managing Osteoporosis in Patients on Long-Term Bisphosphonate Treatment: Report of a Task Force of the American Society for Bone and Mineral Research. J Bone Miner Res. 2016;31(1):16-35.","journal-title":"J Bone Miner Res"},{"issue":"2","key":"key20201119114411_B28","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1111\/odi.12966","article-title":"Drug holiday patterns and bisphosphonate-related osteonecrosis of the jaw","volume":"25","author":"Jung","year":"2019","unstructured":"28. Jung SY, Suh HS, Park JW, Kwon JW. Drug holiday patterns and bisphosphonate-related osteonecrosis of the jaw. Oral Dis. 2019;25(2):471-80.","journal-title":"Oral Dis"},{"issue":"1","key":"key20201119114411_B29","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.amjmed.2012.06.023","article-title":"Bisphosphonate therapy for osteoporosis: benefits, risks, and drug holiday","volume":"126","author":"McClung","year":"2013","unstructured":"29. McClung M, Harris ST, Miller PD, Bauer DC, Davison KS, Dian L, et al. Bisphosphonate therapy for osteoporosis: benefits, risks, and drug holiday. Am J Med. 2013;126(1):13-20.","journal-title":"Am J Med"},{"key":"key20201119114411_B30","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.maturitas.2017.04.008","article-title":"Drug holidays from bisphosphonates and denosumab in postmenopausal osteoporosis: EMAS position statement","volume":"101","author":"Anagnostis","year":"2017","unstructured":"30. Anagnostis P, Paschou SA, Mintziori G, Ceausu I, Depypere H, Lambrinoudaki I, et al. Drug holidays from bisphosphonates and denosumab in postmenopausal osteoporosis: EMAS position statement. Maturitas. 2017;101:23-30.","journal-title":"Maturitas"},{"issue":"8","key":"key20201119114411_B31","doi-asserted-by":"crossref","first-page":"2465","DOI":"10.1007\/s00198-017-4063-7","article-title":"A multicenter retrospective study of the risk factors associated with medication-related osteonecrosis of the jaw after tooth extraction in patients receiving oral bisphosphonate therapy: can primary wound closure and a drug holiday really prevent MRONJ?","volume":"28","author":"Hasegawa","year":"2017","unstructured":"31. Hasegawa T, Kawakita A, Ueda N, Funahara R, Tachibana A, Kobayashi M, et al. A multicenter retrospective study of the risk factors associated with medication-related osteonecrosis of the jaw after tooth extraction in patients receiving oral bisphosphonate therapy: can primary wound closure and a drug holiday really prevent MRONJ? Osteoporos Int. 2017;28(8):2465-73.","journal-title":"Osteoporos Int"},{"issue":"1","key":"key20201119114411_B32","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1007\/s00774-019-01035-7","article-title":"Drug holiday clinical relevance verification for antiresorptive agents in medication-related osteonecrosis cases of the jaw","volume":"38","author":"Hayashida","year":"2020","unstructured":"32. Hayashida S, Yanamoto S, Fujita S, Hasegawa T, Komori T, Kojima Y, et al. Drug holiday clinical relevance verification for antiresorptive agents in medication-related osteonecrosis cases of the jaw. J Bone Miner Metab. 2020;38(1):126-34.","journal-title":"J Bone Miner Metab"},{"issue":"12","key":"key20201119114411_B33","doi-asserted-by":"crossref","first-page":"2397","DOI":"10.1016\/j.joms.2007.08.003","article-title":"Oral bisphosphonate-induced osteonecrosis: risk factors, prediction of risk using serum CTX testing, prevention, and treatment","volume":"65","author":"Marx","year":"2007","unstructured":"33. Marx RE, Cillo JE Jr, Ulloa JJ. Oral bisphosphonate-induced osteonecrosis: risk factors, prediction of risk using serum CTX testing, prevention, and treatment. J Oral Maxillofac Surg. 2007;65(12):2397-410.","journal-title":"J Oral Maxillofac Surg"},{"issue":"8","key":"key20201119114411_B34","doi-asserted-by":"crossref","first-page":"1456","DOI":"10.1016\/j.joms.2014.02.036","article-title":"A C-terminal crosslinking telopeptide test-based protocol for patients on oral bisphosphonates requiring extraction: a prospective single-center controlled study","volume":"72","author":"Hutcheson","year":"2014","unstructured":"34. Hutcheson A, Cheng A, Kunchar R, Stein B, Sambrook P, Goss A. A C-terminal crosslinking telopeptide test-based protocol for patients on oral bisphosphonates requiring extraction: a prospective single-center controlled study. J Oral Maxillofac Surg. 2014;72(8):1456-62.","journal-title":"J Oral Maxillofac Surg"},{"issue":"6","key":"key20201119114411_B35","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.1016\/j.joms.2009.02.004","article-title":"Clinical investigation of C-terminal cross-linking telopeptide test in prevention and management of bisphosphonate-associated osteonecrosis of the jaws","volume":"67","author":"Kunchur","year":"2009","unstructured":"35. Kunchur R, Need A, Hughes T, Goss A. Clinical investigation of C-terminal cross-linking telopeptide test in prevention and management of bisphosphonate-associated osteonecrosis of the jaws. J Oral Maxillofac Surg. 2009;67(6):1167-73.","journal-title":"J Oral Maxillofac Surg"},{"issue":"1","key":"key20201119114411_B36","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1007\/s13167-019-0160-3","article-title":"Value of preoperative CTX serum levels in the prediction of medication-related osteonecrosis of the jaw (MRONJ): a retrospective clinical study","volume":"10","author":"Salgueiro","year":"2019","unstructured":"36. Salgueiro M, Stribos M, Zhang LF, Stevens M, Awad ME, Elsalanty M. Value of preoperative CTX serum levels in the prediction of medication-related osteonecrosis of the jaw (MRONJ): a retrospective clinical study. EPMA J. 2019;10(1):21-9.","journal-title":"EPMA J"},{"issue":"8","key":"key20201119114411_B37","doi-asserted-by":"crossref","first-page":"664.e8","DOI":"10.1016\/j.adaj.2019.03.006","article-title":"Serum C-terminal cross-linking telopeptide level as a predictive biomarker of osteonecrosis after dentoalveolar surgery in patients receiving bisphosphonate therapy: Systematic review and meta-analysis","volume":"150","author":"Awad","year":"2019","unstructured":"37. Awad ME, Sun C, Jernigan J, Elsalanty M. Serum C-terminal cross-linking telopeptide level as a predictive biomarker of osteonecrosis after dentoalveolar surgery in patients receiving bisphosphonate therapy: Systematic review and meta-analysis. J Am Dent Assoc. 2019;150(8):664-75.e8.","journal-title":"J Am Dent Assoc"},{"issue":"1","key":"key20201119114411_B38","first-page":"e26","article-title":"Biomarkers to predict the onset of biphosphonate-related osteonecrosis of the jaw: A systematic review","volume":"24","author":"Lorenzo-Pouso","year":"2019","unstructured":"38. Lorenzo-Pouso AI, Perez-Sayans M, Gonzalez-Palanca S, Chamorro-Petronacci C, Bagan J, Garcia-Garcia A. Biomarkers to predict the onset of biphosphonate-related osteonecrosis of the jaw: A systematic review. Med Oral Patol Oral Cir Bucal. 2019;24(1):e26-e36.","journal-title":"Med Oral Patol Oral Cir Bucal"},{"issue":"1","key":"key20201119114411_B39","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1186\/s40902-018-0153-5","article-title":"Evaluation of mandibular cortical bone ratio on computed tomography images in patients taking bisphosphonates","volume":"40","author":"Koo","year":"2018","unstructured":"39. Koo CH, Lee JH. Evaluation of mandibular cortical bone ratio on computed tomography images in patients taking bisphosphonates. Maxillofac Plast Reconstr Surg. 2018;40(1):17.","journal-title":"Maxillofac Plast Reconstr Surg"},{"issue":"5","key":"key20201119114411_B40","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1016\/j.oooo.2015.02.005","article-title":"Mandibular inferior cortical bone thickness on panoramic radiographs in patients using bisphosphonates","volume":"119","author":"Torres","year":"2015","unstructured":"40. Torres SR, Chen CS, Leroux BG, Lee PP, Hollender LG, Lloid M, et al. Mandibular inferior cortical bone thickness on panoramic radiographs in patients using bisphosphonates. Oral Surg Oral Med Oral Pathol Oral Radiol. 2015;119(5):584-92.","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol"},{"issue":"2","key":"key20201119114411_B41","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1007\/s11282-018-0358-4","article-title":"Effect of bisphosphonate treatment on the jawbone: an exploratory study using periapical and panoramic radiographic evaluation","volume":"35","author":"Barngkgei","year":"2019","unstructured":"41. Barngkgei I, Halboub E, Almashraqi A. Effect of bisphosphonate treatment on the jawbone: an exploratory study using periapical and panoramic radiographic evaluation. Oral Radiol. 2019;35(2):159-70.","journal-title":"Oral Radiol"},{"issue":"2","key":"key20201119114411_B42","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1111\/ger.12121","article-title":"Mandibular cortical indices on cone-beam computed tomography images in osteoporotic women on treatment with oral bisphosphonates","volume":"33","author":"Diniz-Freitas","year":"2016","unstructured":"42. Diniz-Freitas M, Fernandez-Montenegro P, Fernandez-Feijoo J, Limeres-Posse J, Gonzalez-Mosquera A, Vazquez-Garcia E, et al. Mandibular cortical indices on cone-beam computed tomography images in osteoporotic women on treatment with oral bisphosphonates. Gerodontology. 2016;33(2):155-60.","journal-title":"Gerodontology"},{"issue":"2","key":"key20201119114411_B43","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1007\/s11282-017-0293-9","article-title":"Panoramic radiographic features that predict the development of bisphosphonate-related osteonecrosis of the jaw","volume":"34","author":"Kubo","year":"2018","unstructured":"43. Kubo R, Ariji Y, Taniguchi T, Nozawa M, Katsumata A, Ariji E. Panoramic radiographic features that predict the development of bisphosphonate-related osteonecrosis of the jaw. Oral Radiol. 2018;34(2):151-60.","journal-title":"Oral Radiol"},{"issue":"2","key":"key20201119114411_B44","doi-asserted-by":"crossref","first-page":"e250","DOI":"10.4317\/medoral.20963","article-title":"Prevention of medication-related osteonecrosis of the jaws secondary to tooth extractions. A systematic review","volume":"21","author":"Diniz-Freitas","year":"2016","unstructured":"44. Diniz-Freitas M, Limeres J. Prevention of medication-related osteonecrosis of the jaws secondary to tooth extractions. A systematic review. Med Oral Patol Oral Cir Bucal. 2016;21(2):e250-9.","journal-title":"Med Oral Patol Oral Cir Bucal"},{"issue":"1","key":"key20201119114411_B45","first-page":"e141","article-title":"Prophylaxis and antibiotic therapy in management protocols of patients treated with oral and intravenous bisphosphonates","volume":"9","author":"Bermudez-Bejarano","year":"2017","unstructured":"45. Bermudez-Bejarano EB, Serrera-Figallo MA, Gutierrez-Corrales A, Romero-Ruiz MM, Castillo-de-Oyague R, Gutierrez-Perez JL, et al. Prophylaxis and antibiotic therapy in management protocols of patients treated with oral and intravenous bisphosphonates. J Clin Exp Dent. 2017;9(1):e141-e9.","journal-title":"J Clin Exp Dent"},{"issue":"9","key":"key20201119114411_B46","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1016\/j.oraloncology.2012.03.009","article-title":"Tooth extraction in patients on zoledronic acid therapy","volume":"48","author":"Mozzati","year":"2012","unstructured":"46. Mozzati M, Arata V, Gallesio G. Tooth extraction in patients on zoledronic acid therapy. Oral Oncol. 2012;48(9):817-21.","journal-title":"Oral Oncol"},{"issue":"4","key":"key20201119114411_B47","first-page":"859","article-title":"Osteonecrosis of the Jaws: The Awareness of the Patient at Risk","volume":"1","author":"Cavalcanti","year":"2017","unstructured":"47. Cavalcanti EFF, Gomes AOF, Torres SR. Osteonecrosis of the Jaws: The Awareness of the Patient at Risk. Biomed J Sci Tech Res 2017;1(4):859-60.","journal-title":"Biomed J Sci Tech Res"},{"issue":"3","key":"key20201119114411_B48","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1097\/SCS.0000000000002564","article-title":"Medication-Related Osteonecrosis of the Jaw Around Dental Implants: Implant Surgery-Triggered or Implant Presence-Triggered Osteonecrosis?","volume":"27","author":"Giovannacci","year":"2016","unstructured":"48. Giovannacci I, Meleti M, Manfredi M, Mortellaro C, Greco Lucchina A, Bonanini M, et al. Medication-Related Osteonecrosis of the Jaw Around Dental Implants: Implant Surgery-Triggered or Implant Presence-Triggered Osteonecrosis? J Craniofac Surg. 2016;27(3):697-701.","journal-title":"J Craniofac Surg"},{"issue":"3","key":"key20201119114411_B49","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1097\/SCS.0000000000001535","article-title":"Failure risk estimates after dental implants placement associated with plasma rich in growth factor-Endoret in osteoporotic women under bisphosphonate therapy","volume":"26","author":"Mozzati","year":"2015","unstructured":"49. Mozzati M, Arata V, Giacomello M, Del Fabbro M, Gallesio G, Mortellaro C, et al. Failure risk estimates after dental implants placement associated with plasma rich in growth factor-Endoret in osteoporotic women under bisphosphonate therapy. J Craniofac Surg. 2015;26(3):749-55.","journal-title":"J Craniofac Surg"},{"issue":"8","key":"key20201119114411_B50","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1111\/clr.12662","article-title":"Dental implants treatment outcomes in patient under active therapy with alendronate: 3-year follow-up results of a multicenter prospective observational study","volume":"27","author":"Tallarico","year":"2016","unstructured":"50. Tallarico M, Canullo L, Xhanari E, Meloni SM. Dental implants treatment outcomes in patient under active therapy with alendronate: 3-year follow-up results of a multicenter prospective observational study. Clin Oral Implants Res. 2016;27(8):943-9.","journal-title":"Clin Oral Implants Res"},{"issue":"12","key":"key20201119114411_B51","doi-asserted-by":"crossref","first-page":"1945","DOI":"10.1016\/j.jcms.2016.09.018","article-title":"Clinical features of peri-implant medication-related osteonecrosis of the jaw: Is there an association to peri-implantitis?","volume":"44","author":"Troeltzsch","year":"2016","unstructured":"51. Troeltzsch M, Cagna D, Stahler P, Probst F, Kaeppler G, Troeltzsch M, et al. Clinical features of peri-implant medication-related osteonecrosis of the jaw: Is there an association to peri-implantitis? J Craniomaxillofac Surg. 2016;44(12):1945-51.","journal-title":"J Craniomaxillofac Surg"},{"issue":"1","key":"key20201119114411_B52","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1186\/s40729-016-0041-7","article-title":"Dental implants in patients treated with antiresorptive medication - a systematic literature review","volume":"2","author":"Walter","year":"2016","unstructured":"52. Walter C, Al-Nawas B, Wolff T, Schiegnitz E, Grotz KA. Dental implants in patients treated with antiresorptive medication - a systematic literature review. Int J Implant Dent. 2016;2(1):9.","journal-title":"Int J Implant Dent"},{"issue":"11","key":"key20201119114411_B53","doi-asserted-by":"crossref","first-page":"1525","DOI":"10.1016\/j.joen.2009.07.020","article-title":"A retrospective clinical and radiographic study on healing of periradicular lesions in patients taking oral bisphosphonates","volume":"35","author":"Hsiao","year":"2009","unstructured":"53. Hsiao A, Glickman G, He J. A retrospective clinical and radiographic study on healing of periradicular lesions in patients taking oral bisphosphonates. J Endod. 2009;35(11):1525-8.","journal-title":"J Endod"},{"issue":"5","key":"key20201119114411_B54","doi-asserted-by":"crossref","first-page":"1887","DOI":"10.1007\/s00198-015-3437-y","article-title":"Association of osteoporosis and bone medication with the periodontal condition in elderly women","volume":"27","author":"Penoni","year":"2016","unstructured":"54. Penoni DC, Torres SR, Farias ML, Fernandes TM, Luiz RR, Leao AT. Association of osteoporosis and bone medication with the periodontal condition in elderly women. Osteoporos Int. 2016;27(5):1887-96.","journal-title":"Osteoporos Int"},{"issue":"2","key":"key20201119114411_B55","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.oooo.2018.09.008","article-title":"Medication-related osteonecrosis of the jaw: definition and best practice for prevention, diagnosis, and treatment","volume":"127","author":"Nicolatou-Galitis","year":"2019","unstructured":"55. Nicolatou-Galitis O, Schiodt M, Mendes RA, Ripamonti C, Hope S, Drudge-Coates L, et al. Medication-related osteonecrosis of the jaw: definition and best practice for prevention, diagnosis, and treatment. Oral Surg Oral Med Oral Pathol Oral Radiol. 2019;127(2):117-35.","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol"},{"issue":"2","key":"key20201119114411_B56","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.oooo.2014.05.006","article-title":"Osteonecrosis of the jaw in patients treated with oral and intravenous bisphosphonates: experience in Sweden","volume":"118","author":"Hallmer","year":"2014","unstructured":"56. Hallmer F, Bjornland T, Nicklasson A, Becktor JP, Andersson G. Osteonecrosis of the jaw in patients treated with oral and intravenous bisphosphonates: experience in Sweden. Oral Surg Oral Med Oral Pathol Oral Radiol. 2014;118(2):202-8.","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol"},{"issue":"3","key":"key20201119114411_B57","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/j.ajodo.2008.08.017","article-title":"Optimizing orthodontic treatment in patients taking bisphosphonates for osteoporosis","volume":"135","author":"Zahrowski","year":"2009","unstructured":"57. Zahrowski JJ. Optimizing orthodontic treatment in patients taking bisphosphonates for osteoporosis. Am J Orthod Dentofacial Orthop. 2009;135(3):361-74.","journal-title":"Am J Orthod Dentofacial Orthop"},{"issue":"3","key":"key20201119114411_B58","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/j.ajodo.2006.11.002","article-title":"Orthodontic treatment of patients using bisphosphonates: a report of 2 cases","volume":"131","author":"Rinchuse","year":"2007","unstructured":"58. Rinchuse DJ, Rinchuse DJ, Sosovicka MF, Robison JM, Pendleton R. Orthodontic treatment of patients using bisphosphonates: a report of 2 cases. Am J Orthod Dentofacial Orthop. 2007;131(3):321-6.","journal-title":"Am J Orthod Dentofacial Orthop"},{"issue":"7","key":"key20201119114411_B59","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1016\/j.ijom.2015.03.013","article-title":"Comparison of the prognosis of bisphosphonate-related osteonecrosis of the jaw caused by oral and intravenous bisphosphonates","volume":"44","author":"Shintani","year":"2015","unstructured":"59. Shintani T, Hayashido Y, Mukasa H, Akagi E, Hoshino M, Ishida Y, et al. Comparison of the prognosis of bisphosphonate-related osteonecrosis of the jaw caused by oral and intravenous bisphosphonates. Int J Oral Maxillofac Surg. 2015;44(7):840-4.","journal-title":"Int J Oral Maxillofac Surg"},{"issue":"3","key":"key20201119114411_B60","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1007\/s00223-013-9747-1","article-title":"Ninety-one osteoporosis patients affected with bisphosphonate-related osteonecrosis of the jaw: a case series","volume":"93","author":"Mercer","year":"2013","unstructured":"60. Mercer E, Norton T, Woo S, Treister N, Dodson TB, Solomon DH. Ninety-one osteoporosis patients affected with bisphosphonate-related osteonecrosis of the jaw: a case series. Calcif Tissue Int. 2013;93(3):241-8.","journal-title":"Calcif Tissue Int"},{"issue":"8","key":"key20201119114411_B61","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1016\/j.bjoms.2016.06.015","article-title":"Conservative surgical management of patients with bisphosphonate-related osteonecrosis of the jaws: a series of 120 patients","volume":"54","author":"Nisi","year":"2016","unstructured":"61. Nisi M, La Ferla F, Karapetsa D, Gennai S, Ramaglia L, Graziani F, et al. Conservative surgical management of patients with bisphosphonate-related osteonecrosis of the jaws: a series of 120 patients. Br J Oral Maxillofac Surg. 2016;54(8):930-5.","journal-title":"Br J Oral Maxillofac Surg"},{"issue":"1","key":"key20201119114411_B62","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.jormas.2019.02.011","article-title":"The use of Platelet-rich Fibrin in the management of medication-related osteonecrosis of the jaw: A case series","volume":"121","author":"Mourao","year":"2020","unstructured":"62. Mourao FABC, Calasans-Maia MD, Del Fabbro M, Le Drapper Vieira F, Coutinho de Mello Machado R, Capella R, et al. The use of Platelet-rich Fibrin in the management of medication-related osteonecrosis of the jaw: A case series. J Stomatol Oral Maxillofac Surg. 2020;121(1):84-9.","journal-title":"J Stomatol Oral Maxillofac Surg"},{"issue":"12","key":"key20201119114411_B63","doi-asserted-by":"crossref","first-page":"2445","DOI":"10.1002\/jbmr.3237","article-title":"Short-Term Teriparatide and Recombinant Human Bone Morphogenetic Protein-2 for Regenerative Approach to Medication-Related Osteonecrosis of the Jaw: A Preliminary Study","volume":"32","author":"Jung","year":"2017","unstructured":"63. Jung J, Yoo HY, Kim GT, Lee JW, Lee YA, Kim DY, et al. Short-Term Teriparatide and Recombinant Human Bone Morphogenetic Protein-2 for Regenerative Approach to Medication-Related Osteonecrosis of the Jaw: A Preliminary Study. J Bone Miner Res. 2017;32(12):2445-52.","journal-title":"J Bone Miner Res"},{"issue":"12","key":"key20201119114411_B64","doi-asserted-by":"crossref","first-page":"1558","DOI":"10.1016\/j.ijom.2015.07.018","article-title":"Administration of teriparatide improves the symptoms of advanced bisphosphonate-related osteonecrosis of the jaw: preliminary findings","volume":"44","author":"Kakehashi","year":"2015","unstructured":"64. Kakehashi H, Ando T, Minamizato T, Nakatani Y, Kawasaki T, Ikeda H, et al. Administration of teriparatide improves the symptoms of advanced bisphosphonate-related osteonecrosis of the jaw: preliminary findings. Int J Oral Maxillofac Surg. 2015;44(12):1558-64.","journal-title":"Int J Oral Maxillofac Surg"}],"container-title":["Archives of Endocrinology and Metabolism"],"original-title":[],"language":"en","deposited":{"date-parts":[[2021,4,14]],"date-time":"2021-04-14T21:22:09Z","timestamp":1618435329000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S2359-39972020005008204&lng=en&nrm=iso"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10,21]]},"references-count":64,"alternative-id":["10.20945\/2359-3997000000301"],"URL":"https:\/\/doi.org\/10.20945\/2359-3997000000301","relation":{},"ISSN":["2359-3997","2359-4292"],"issn-type":[{"type":"print","value":"2359-3997"},{"type":"electronic","value":"2359-4292"}],"subject":[],"published":{"date-parts":[[2020,10,21]]}}}