{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T10:28:09Z","timestamp":1777976889211,"version":"3.51.4"},"reference-count":33,"publisher":"Archives of Endocrinology and Metabolism","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,3,23]]},"DOI":"10.20945\/2359-3997000000456","type":"journal-article","created":{"date-parts":[[2022,3,25]],"date-time":"2022-03-25T12:15:03Z","timestamp":1648210503000},"source":"Crossref","is-referenced-by-count":7,"title":["The remission phase in adolescents and young adults with newly diagnosed type 1 diabetes mellitus: prevalence, predicting factors and glycemic control during follow-up"],"prefix":"10.20945","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4239-5229","authenticated-orcid":false,"given":"Meriem","family":"Yazidi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0497-0365","authenticated-orcid":false,"given":"Sana","family":"Mahjoubi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4278-9447","authenticated-orcid":false,"given":"Ibtissem","family":"Oueslati","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5683-0850","authenticated-orcid":false,"given":"Fatma","family":"Chaker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7991-9885","authenticated-orcid":false,"given":"Melika","family":"Chihaoui","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"8510","reference":[{"key":"key20220325081415_B1","article-title":"The remission phase in type 1 diabetes: Changing epidemiology, definitions, and emerging immuno-metabolic mechanisms","author":"Zhong","year":"2019","unstructured":"1 Zhong T, Tang R, Gong S, Li J, Li X, Zhou Z. The remission phase in type 1 diabetes: Changing epidemiology, definitions, and emerging immuno-metabolic mechanisms. Diabetes Metab Res Rev. 2019;e3207.","journal-title":"Diabetes Metab Res Rev"},{"issue":"2","key":"key20220325081415_B2","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1046\/j.1365-2796.1999.00426.x","article-title":"Factors predicting clinical remission in adult patients with type 1 diabetes","volume":"245","author":"Scholin","year":"1999","unstructured":"2 Scholin A, Berne C, Schvarcz E, Karlsson FA, Bjork E. Factors predicting clinical remission in adult patients with type 1 diabetes. J Intern Med 1999;245(2):155-62.","journal-title":"J Intern Med"},{"issue":"8","key":"key20220325081415_B3","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1016\/j.jdiacomp.2015.09.002","article-title":"Influence of remission and its duration on development of early microvascular complications in young adults with type 1 diabetes","volume":"29","author":"Niedzwiecki","year":"2015","unstructured":"3 Niedzwiecki P, Pilacinski S, Uruska A, Adamska A, Naskret D, Zozulinska-Ziolkiewicz D. Influence of remission and its duration on development of early microvascular complications in young adults with type 1 diabetes. J Diabetes Complications. 2015;29(8):1105-11.","journal-title":"J Diabetes Complications"},{"issue":"9","key":"key20220325081415_B4","doi-asserted-by":"crossref","first-page":"1585","DOI":"10.1515\/JPEM.2001.14.9.1585","article-title":"Factors influencing remission phase in children with type 1 diabetes mellitus","volume":"14","author":"Buyukgebiz","year":"2001","unstructured":"4 Buyukgebiz A, Cemeroglu AP, Bober E, Mohn A, Chiarelli F. Factors influencing remission phase in children with type 1 diabetes mellitus. J Pediatr Endocrinol Metab 2001;14(9):1585-96.","journal-title":"J Pediatr Endocrinol Metab"},{"key":"key20220325081415_B5","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1093\/ajcn\/64.4.650","article-title":"Anthropometric reference data for international use: recommendations from a World Health Organization Expert Committee","volume":"64","author":"Onis","year":"1996","unstructured":"5 Onis M, Habicht JP. Anthropometric reference data for international use: recommendations from a World Health Organization Expert Committee. Am J Clin Nutr. 1996;64:650-8.","journal-title":"Am J Clin Nutr"},{"issue":"5","key":"key20220325081415_B6","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1111\/j.1464-5491.2004.01175.x","article-title":"Normal weight promotes remission and low number of islet antibodies prolong the duration of remission in type 1 diabetes","volume":"21","author":"Scholin","year":"2004","unstructured":"6 Scholin A, Torn C, Nystrom L, Berne C, Arnqvist H, Blohme G, et al. Normal weight promotes remission and low number of islet antibodies prolong the duration of remission in type 1 diabetes. Diabet Med. 2004;21(5):447-55.","journal-title":"Diabet Med"},{"issue":"2","key":"key20220325081415_B7","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1111\/j.1464-5491.2010.03191.x","article-title":"Diabetes Incidence Study Group in Sweden (DISS). Proinsulin\/C-peptide ratio, glucagon and remission in new-onset Type 1 diabetes mellitus in young adults","volume":"28","author":"Sch\u00f6lin","year":"2011","unstructured":"7 Sch\u00f6lin A, Nystr\u00f6m L, Arnqvist H, Bolinder J, Bj\u00f6rk E, Berne C, et al.; Diabetes Incidence Study Group in Sweden (DISS). Proinsulin\/C-peptide ratio, glucagon and remission in new-onset Type 1 diabetes mellitus in young adults. Diabet Med. 2011;28(2):156-61.","journal-title":"Diabet Med"},{"issue":"4","key":"key20220325081415_B8","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1111\/j.1464-5491.2011.03467.x","article-title":"Smoking and other factors associated with short-term partial remission of type 1 diabetes in adults","volume":"29","author":"Pilacinski","year":"2012","unstructured":"8 Pilacinski S, Adler AI, Zozulinska-Ziolkiewicz DA, Gawrecki A, Wierusz-Wysocka B. Smoking and other factors associated with short-term partial remission of type 1 diabetes in adults. Diabet Med. 2012;29(4):464-9.","journal-title":"Diabet Med"},{"issue":"9","key":"key20220325081415_B9","doi-asserted-by":"crossref","first-page":"1585","DOI":"10.1515\/JPEM.2001.14.9.1585","article-title":"Factors influencing remission phase in children with type 1 diabetes mellitus","volume":"14","author":"Buyukgebiz","year":"2001","unstructured":"9 Buyukgebiz A, Cemeroglu AP, Bober E, Mohn A, Chiarelli F. Factors influencing remission phase in children with type 1 diabetes mellitus. J Pediatr Endocrinol Metab. 2001;14(9):1585-96.","journal-title":"J Pediatr Endocrinol Metab"},{"issue":"8","key":"key20220325081415_B10","doi-asserted-by":"crossref","first-page":"1384","DOI":"10.2337\/dc08-1987","article-title":"New definition for the partial remission period in children and adolescents with type 1 diabetes","volume":"32","author":"Mortensen","year":"2009","unstructured":"10 Mortensen HB, Hougaard P, Swift P, Hansen L, Holl RW, Hoey H, et al. New definition for the partial remission period in children and adolescents with type 1 diabetes. Diabetes Care. 2009;32(8):1384-90.","journal-title":"Diabetes Care"},{"issue":"6","key":"key20220325081415_B11","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1111\/pedi.12413","article-title":"Factors contributing to partial remission in type 1 diabetes: analysis based on the insulin dose-adjusted HbA1c in 3657 children and adolescents from Germany and Austria","volume":"18","author":"Nagl","year":"2017","unstructured":"11 Nagl K, Hermann JM, Plamper M, Schr\u00f6der C, Dost A, Kordonouri O, et al. Factors contributing to partial remission in type 1 diabetes: analysis based on the insulin dose-adjusted HbA1c in 3657 children and adolescents from Germany and Austria. Pediatr Diabetes. 2017 Sep;18(6):428-34.","journal-title":"Pediatr Diabetes"},{"issue":"5","key":"key20220325081415_B12","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.2337\/diacare.27.5.1207","article-title":"Complete long-term recovery of beta-cell function in autoimmune type 1 diabetes after insulin treatment","volume":"27","author":"Karges","year":"2004","unstructured":"12 Karges B, Durinovic-Bello I, Heinze E, Boehm BO, Debatin KM, Karges W. Complete long-term recovery of beta-cell function in autoimmune type 1 diabetes after insulin treatment. Diabetes Care 2004;27(5):1207-8.","journal-title":"Diabetes Care"},{"issue":"4","key":"key20220325081415_B13","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1515\/JPEM.2001.14.4.435","article-title":"Partial remission phase and metabolic control in type 1 diabetes mellitus in children and adolescents","volume":"14","author":"Bober","year":"2001","unstructured":"13 Bober E, Dundar B, Buyukgebiz A. Partial remission phase and metabolic control in type 1 diabetes mellitus in children and adolescents. J Pediatr Endocrinol Metab. 2001;14(4):435-41.","journal-title":"J Pediatr Endocrinol Metab"},{"key":"key20220325081415_B14","doi-asserted-by":"crossref","first-page":"1072","DOI":"10.2337\/diacare.23.8.1072","article-title":"Use of an iselet cell antibody assay to identify type 1 diabetic patients with rapid decrease in C-peptid levels after clinical onset: Belgian Diabetes Registry","volume":"23","author":"Decochez","year":"2000","unstructured":"14 Decochez K, Keymeulen B, Somerst G, Dorchy H, De Leeuw IH, Mathieu C, et al. Use of an iselet cell antibody assay to identify type 1 diabetic patients with rapid decrease in C-peptid levels after clinical onset: Belgian Diabetes Registry. Diabetes Care. 2000;23:1072-8.","journal-title":"Diabetes Care"},{"issue":"1","key":"key20220325081415_B15","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1055\/s-2007-948214","article-title":"Shorter remission period in young versus older children with diabetes mellitus type 1","volume":"115","author":"Dost","year":"2007","unstructured":"15 Dost A, Herbst A, Kintzel K, Haberland H, Roth CL, Gortner L, et al. Shorter remission period in young versus older children with diabetes mellitus type 1. Exp Clin Endocrinol Diabetes 2007;115(1):33-7.","journal-title":"Exp Clin Endocrinol Diabetes"},{"issue":"Part I","key":"key20220325081415_B16","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1111\/j.1399-5448.2008.00376.x","article-title":"Young children (<5 yr) and adolescents (>12 yr) with type 1 diabetes mellitus have low rate of partial remission: diabetic ketoacidosis is an important risk factor","volume":"9","author":"Bowdena","year":"2008","unstructured":"16 Bowdena SA, Duckb MM, Hoffmana RP. Young children (<5 yr) and adolescents (>12 yr) with type 1 diabetes mellitus have low rate of partial remission: diabetic ketoacidosis is an important risk factor. Pediatric Diabetes. 2008;9(Part I):197-201.","journal-title":"Pediatric Diabetes"},{"issue":"3","key":"key20220325081415_B17","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1007\/s004310050796","article-title":"Does the long-term clinical course of type 1 diabetes mellitus differ in patients with prepubertal and pubertal onset? Results of the Berlin retinopathy study","volume":"157","author":"Kordonouri","year":"1998","unstructured":"17 Kordonouri O, Danne T, Enders I, Weber B. Does the long-term clinical course of type 1 diabetes mellitus differ in patients with prepubertal and pubertal onset? Results of the Berlin retinopathy study. Eur J Pediatr. 1998;157(3):202-7.","journal-title":"Eur J Pediatr"},{"key":"key20220325081415_B18","doi-asserted-by":"crossref","first-page":"1835","DOI":"10.1007\/s00125-008-1106-9","article-title":"Ethnicity and social deprivation independently influence metabolic control in children with type 1 diabetes","volume":"51","author":"Carter","year":"2008","unstructured":"18 Carter JP, Cutfield WS, Hofman PL, Gunn AJ, Wilson DA, Reed PW, et al. Ethnicity and social deprivation independently influence metabolic control in children with type 1 diabetes. Diabetologia. 2008;51:1835-42.","journal-title":"Diabetologia"},{"issue":"2","key":"key20220325081415_B19","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1111\/j.1399-543X.2006.00155.x","article-title":"The honeymoon phase in children with type 1 diabetes mellitus: frequency, duration, and influential factors","volume":"7","author":"Abdul-Rasoul","year":"2006","unstructured":"19 Abdul-Rasoul M, Habib H, Al-Khouly M. The honeymoon phase in children with type 1 diabetes mellitus: frequency, duration, and influential factors. Pediatr Diabetes. 2006;7(2):101-7.","journal-title":"Pediatr Diabetes"},{"issue":"6","key":"key20220325081415_B20","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1111\/pedi.12413","article-title":"Factors contributing to partial remission in type 1 diabetes: analysis based on the insulin dose-adjusted HbA1c in 3657 children and adolescents from Germany and Austria","volume":"18","author":"Nagl","year":"2017","unstructured":"20 Nagl K, Hermann JM, Plamper M, Schroder C, Dost A, Kordonouri O, et al. Factors contributing to partial remission in type 1 diabetes: analysis based on the insulin dose-adjusted HbA1c in 3657 children and adolescents from Germany and Austria. Pediatr Diabetes 2017;18(6):428-34.","journal-title":"Pediatr Diabetes"},{"issue":"11","key":"key20220325081415_B21","doi-asserted-by":"crossref","first-page":"1166","DOI":"10.1111\/j.1651-2227.1997.tb14837.x","article-title":"Age governs gender-dependent islet cell autoreactivity and predicts the clinical course in childhood IDDM","volume":"86","author":"Ortqvist","year":"1997","unstructured":"21 Ortqvist E, Falorni A, Scheynius A, Persson B, Lernmark A. Age governs gender-dependent islet cell autoreactivity and predicts the clinical course in childhood IDDM. Acta Paediatr. 1997;86(11):1166-71.","journal-title":"Acta Paediatr"},{"key":"key20220325081415_B22","doi-asserted-by":"crossref","first-page":"851378","DOI":"10.1155\/2014\/851378","article-title":"Characteristics and determinants of partial remission in children with type 1 diabetes using the insulin-dose-adjusted A1C definition","volume":"2014","author":"Pecheur","year":"2014","unstructured":"22 Pecheur A, Barrea T, Vandooren V, Beauloye V, Robert A, Lysy PA. Characteristics and determinants of partial remission in children with type 1 diabetes using the insulin-dose-adjusted A1C definition. J Diabetes Res. 2014;2014:851378.","journal-title":"J Diabetes Res"},{"issue":"46","key":"key20220325081415_B23","doi-asserted-by":"crossref","first-page":"74415","DOI":"10.18632\/oncotarget.12766","article-title":"Characterization of pancreatic glucagon-producing tumors and pituitary gland tumors in transgenic mice overexpressing MYCN in hGFAP-positive cells","volume":"7","author":"Fielitz","year":"2016","unstructured":"23 Fielitz K, Althoff K, De Preter K, Nonnekens J, Ohli J, Elges S, et al. Characterization of pancreatic glucagon-producing tumors and pituitary gland tumors in transgenic mice overexpressing MYCN in hGFAP-positive cells. Oncotarget. 2016;7(46):74415-26.","journal-title":"Oncotarget"},{"issue":"6","key":"key20220325081415_B24","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1530\/eje.0.1450757","article-title":"Is the process of beta-cell destruction in type 1 diabetes at time of diagnosis more extensive in females than in males?","volume":"145","author":"Pozzilli","year":"2001","unstructured":"24 Pozzilli P, Mesturino CA, Crino A, Gross TM, Jeng LM, Visalli N, et al. Is the process of beta-cell destruction in type 1 diabetes at time of diagnosis more extensive in females than in males? Eur J Endocrinol 2001;145(6):757-61.","journal-title":"Eur J Endocrinol"},{"key":"key20220325081415_B25","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1111\/dom.14022","article-title":"Impact of obesity on the increasing incidence of type 1 diabetes","volume":"22","author":"Buzzetti","year":"2020","unstructured":"25 Buzzetti R, Zampetti S, Pozzilli P. Impact of obesity on the increasing incidence of type 1 diabetes. Diabetes Obes Metab. 2020;22:1009-13.","journal-title":"Diabetes Obes Metab"},{"issue":"1","key":"key20220325081415_B26","doi-asserted-by":"crossref","first-page":"9","DOI":"10.2337\/diacare.13.1.9","article-title":"Impact of physical fitness and glycemic control on in vivo insulin action in adolescents with IDDM","volume":"13","author":"Arslanian","year":"1990","unstructured":"26 Arslanian S, Nixon PA, Becker D, Drash AL. Impact of physical fitness and glycemic control on in vivo insulin action in adolescents with IDDM. Diabetes Care. 1990;13(1):9-15.","journal-title":"Diabetes Care"},{"issue":"3","key":"key20220325081415_B27","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1111\/j.1464-5491.2007.02357.x","article-title":"Insulin sensitivity in type 1 diabetic children and adolescents","volume":"25","author":"Szadkowska","year":"2008","unstructured":"27 Szadkowska A, Pietrzak I, Mianowska B, Bodalska-Lipinska J, Keenan HA, Toporowska-Kowalska E, et al. Insulin sensitivity in type 1 diabetic children and adolescents. Diabet Med. 2008;25(3):282-8.","journal-title":"Diabet Med"},{"issue":"11","key":"key20220325081415_B28","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1515\/jpem-2017-0100","article-title":"Markers influencing the presence of partial clinical remission in patients with newly diagnosed type 1 diabetes","volume":"30","author":"Pyziak","year":"2017","unstructured":"28 Pyziak A, Zmyslowska A, Bobeff K, Malachowska B, Fendler W, Wyka K, et al. Markers influencing the presence of partial clinical remission in patients with newly diagnosed type 1 diabetes. J Pediatr Endocrinol Metab. 2017;30(11):1147-53.","journal-title":"J Pediatr Endocrinol Metab"},{"issue":"12","key":"key20220325081415_B29","first-page":"4619","article-title":"Prognostic factors for the course of beta cell function in autoimmune diabetes","volume":"85","author":"Torn","year":"2000","unstructured":"29 Torn C, Landin-Olsson M, Lernmark A, Palmer JP, Arnqvist HJ, Blohme G, et al. Prognostic factors for the course of beta cell function in autoimmune diabetes. J Clin Endocrinol Metab. 2000;85(12):4619-23.","journal-title":"J Clin Endocrinol Metab"},{"issue":"5","key":"key20220325081415_B30","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0176860","article-title":"A predictive model for lack of partial clinical remission in new-onset pediatric type 1 diabetes","volume":"12","author":"Marino","year":"2017","unstructured":"30 Marino KR, Lundberg RL, Jasrotia A, Maranda LS, Thompson MJ, Barton BA, et al. A predictive model for lack of partial clinical remission in new-onset pediatric type 1 diabetes. PLoS One 2017;12(5):e0176860.","journal-title":"PLoS One"},{"key":"key20220325081415_B31","doi-asserted-by":"crossref","first-page":"34","DOI":"10.4158\/EP.12.S1.34","article-title":"Insights from the diabetes control and complications trial\/epidemiology of diabetes interventions and complications study on the use of intensive glycemic treatment to reduce the risk of complications of type 1 diabetes","volume":"12","author":"Genuth","year":"2006","unstructured":"31 Genuth S. Insights from the diabetes control and complications trial\/epidemiology of diabetes interventions and complications study on the use of intensive glycemic treatment to reduce the risk of complications of type 1 diabetes. Endocrine Practice. 2006;12 Suppl 1: 34-41.","journal-title":"Endocrine Practice"},{"key":"key20220325081415_B32","doi-asserted-by":"crossref","first-page":"2198","DOI":"10.2337\/dc08-0864","article-title":"A1C variability and the risk of microvascular complications in type 1 diabetes - Data from the Diabetes Control and Complications Trial","volume":"31","author":"Kilpatrick","year":"2008","unstructured":"32 Kilpatrick ES, Rigby AS, Atkin S. A1C variability and the risk of microvascular complications in type 1 diabetes - Data from the Diabetes Control and Complications Trial. Diabetes Care. 2008;31:2198-202.","journal-title":"Diabetes Care"},{"issue":"5","key":"key20220325081415_B33","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1038\/nrendo.2015.8","article-title":"Combination immunotherapies for type 1 diabetes mellitus","volume":"11","author":"Pozzilli","year":"2015","unstructured":"33 Pozzilli P, Maddaloni E, Buzzetti R. Combination immunotherapies for type 1 diabetes mellitus. Nat Rev Endocrinol. 2015;11(5):289-97.","journal-title":"Nat Rev Endocrinol"}],"container-title":["Archives of Endocrinology and Metabolism"],"original-title":[],"language":"en","deposited":{"date-parts":[[2022,3,25]],"date-time":"2022-03-25T12:15:35Z","timestamp":1648210535000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.aem-sbem.com\/article\/the-remission-phase-in-adolescents-and-young-adults-with-newly-diagnosed-type-1-diabetes-mellitus-prevalence-predicting-factors-and-glycemic-control-during-follow-up\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3,23]]},"references-count":33,"alternative-id":["10.20945\/2359-3997000000456"],"URL":"https:\/\/doi.org\/10.20945\/2359-3997000000456","relation":{},"ISSN":["2359-3997","2359-4292"],"issn-type":[{"value":"2359-3997","type":"print"},{"value":"2359-4292","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,3,23]]}}}