{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T09:04:20Z","timestamp":1782205460391,"version":"3.54.5"},"reference-count":28,"publisher":"Archives of Endocrinology and Metabolism","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,6,3]]},"DOI":"10.20945\/2359-3997000000480","type":"journal-article","created":{"date-parts":[[2022,6,6]],"date-time":"2022-06-06T13:31:57Z","timestamp":1654522317000},"source":"Crossref","is-referenced-by-count":5,"title":["Precipitating factors of diabetic ketoacidosis in type 1 diabetes patients at a tertiary hospital: a cross-sectional study with a two-time-period comparison"],"prefix":"10.20945","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1578-6096","authenticated-orcid":false,"given":"Laura Emanuelle da Rosa Carlos","family":"Monteiro","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2181-0697","authenticated-orcid":false,"given":"Sheila Piccoli","family":"Garcia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5260-3001","authenticated-orcid":false,"given":"Leonardo Grabinski","family":"Bottino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9676-3170","authenticated-orcid":false,"given":"Julia Luchese","family":"Custodio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9093-383X","authenticated-orcid":false,"given":"Gabriela Heiden","family":"Telo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2128-8387","authenticated-orcid":false,"given":"Beatriz D.","family":"Schaan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"8510","reference":[{"issue":"7","key":"key20220606093152_B1","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2017-016587","article-title":"Incidence and prevalence of diabetic ketoacidosis (DKA) among adults with type 1 diabetes mellitus (T1D): A systematic literature review","volume":"7","author":"Farsani","year":"2017","unstructured":"Farsani SF, Brodovicz K, Soleymanlou N, Marquard J, Wissinger E, Maiese BA. Incidence and prevalence of diabetic ketoacidosis (DKA) among adults with type 1 diabetes mellitus (T1D): A systematic literature review. BMJ Open. 2017;7(7).","journal-title":"BMJ Open"},{"issue":"9","key":"key20220606093152_B2","doi-asserted-by":"crossref","first-page":"1870","DOI":"10.2337\/dc17-1583","article-title":"Trends in hospital admission for diabetic ketoacidosis in adults with type 1 and type 2 diabetes in England, 1998-2013: a retrospective cohort study","volume":"41","author":"Zhong","year":"2018","unstructured":"Zhong VW, Juhaeri J, Mayer-Davis EJ. Trends in hospital admission for diabetic ketoacidosis in adults with type 1 and type 2 diabetes in England, 1998-2013: a retrospective cohort study. Diabetes Care. 2018;41(9):1870-7.","journal-title":"Diabetes Care"},{"issue":"5","key":"key20220606093152_B3","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.2337\/dc19-2449","article-title":"Trends in emergency department visits and inpatient admissions for hyperglycemic crises in adults with diabetes in the U.S., 2006-2015","volume":"43","author":"Benoit","year":"2020","unstructured":"Benoit SR, Hora I, Pasquel FJ, Gregg EW, Albright AL, Imperatore G. Trends in emergency department visits and inpatient admissions for hyperglycemic crises in adults with diabetes in the U.S., 2006-2015. Diabetes Care. 2020;43(5):1057-64.","journal-title":"Diabetes Care"},{"issue":"10","key":"key20220606093152_B4","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/j.cppeds.2012.07.002","article-title":"Type 1 diabetes: Current concepts in epidemiology, pathophysiology, clinical care, and research","volume":"42","author":"Gan","year":"2012","unstructured":"Gan MJ, Albanese-O\u2019Neill A, Haller MJ. Type 1 diabetes: Current concepts in epidemiology, pathophysiology, clinical care, and research. Curr Probl Pediatr Adolesc Health Care. 2012;42(10): 269-91.","journal-title":"Curr Probl Pediatr Adolesc Health Care"},{"issue":"10","key":"key20220606093152_B5","doi-asserted-by":"crossref","first-page":"1361","DOI":"10.1111\/dme.13427","article-title":"The cost of treating diabetic ketoacidosis in the UK: a national survey of hospital resource use","volume":"34","author":"Dhatariya","year":"2017","unstructured":"Dhatariya KK, Skedgel C, Fordham R. The cost of treating diabetic ketoacidosis in the UK: a national survey of hospital resource use. Diabet Med. 2017;34(10):1361-6.","journal-title":"Diabet Med"},{"issue":"1","key":"key20220606093152_B6","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.diabres.2011.11.006","article-title":"Precipitating factors of diabetic ketoacidosis at a public hospital in a middle-income country","volume":"96","author":"Weinert","year":"2012","unstructured":"Weinert LS, Scheffel RS, Severo MD, Cioffi AP, Tel\u00f3 GH, Boschi A, et al. Precipitating factors of diabetic ketoacidosis at a public hospital in a middle-income country. Diabetes Res Clin Pract. 2012;96(1):29-34.","journal-title":"Diabetes Res Clin Pract"},{"issue":"2","key":"key20220606093152_B7","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1016\/j.diabres.2012.05.004","article-title":"Characteristics of diabetic ketoacidosis in Chinese adults and adolescents \u2013 a teaching hospital-based analysis","volume":"97","author":"Tan","year":"2012","unstructured":"Tan H, Zhou Y, Yu Y. Characteristics of diabetic ketoacidosis in Chinese adults and adolescents \u2013 a teaching hospital-based analysis. Diabetes Res Clin Pract. 2012;97(2):306-12.","journal-title":"Diabetes Res Clin Pract"},{"issue":"4","key":"key20220606093152_B8","doi-asserted-by":"crossref","first-page":"e938","DOI":"10.1542\/peds.2013-2795","article-title":"Trends in the Prevalence of Ketoacidosis at Diabetes Diagnosis: The SEARCH for Diabetes in Youth Study","volume":"133","author":"Dabelea","year":"2014","unstructured":"Dabelea D, Rewers A, Stafford JM, Standiford DA, Lawrence JM, Saydah S, et al. Trends in the Prevalence of Ketoacidosis at Diabetes Diagnosis: The SEARCH for Diabetes in Youth Study. Pediatrics. 2014;133(4):e938-45.","journal-title":"Pediatrics"},{"issue":"4","key":"key20220606093152_B9","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1038\/nrendo.2016.15","article-title":"Diabetic emergencies-ketoacidosis, hyperglycaemic hyperosmolar state and hypoglycaemia","volume":"12","author":"Umpierrez","year":"2016","unstructured":"Umpierrez G, Korytkowski M. Diabetic emergencies-ketoacidosis, hyperglycaemic hyperosmolar state and hypoglycaemia. Nat Rev Endocrinol. 2016;12(4):222-32.","journal-title":"Nat Rev Endocrinol"},{"issue":"4","key":"key20220606093152_B10","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/j.jclinepi.2007.11.008","article-title":"The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies","volume":"61","author":"von Elm","year":"2008","unstructured":"von Elm E, Altman DG, Egger M, Pocock SJ, G\u00f8tzsche PC, Vandenbroucke JP. The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies. J Clin Epidemiol. 2008;61(4):344-9.","journal-title":"J Clin Epidemiol"},{"issue":"7","key":"key20220606093152_B11","doi-asserted-by":"crossref","first-page":"1335","DOI":"10.2337\/dc09-9032","article-title":"Hyperglycemic crises in adult patients with diabetes","volume":"32","author":"Kitabchi","year":"2009","unstructured":"Kitabchi AE, Umpierrez GE, Miles JM, Fisher JN. Hyperglycemic crises in adult patients with diabetes. Diabetes Care. 2009;32(7):1335-43.","journal-title":"Diabetes Care"},{"issue":"10","key":"key20220606093152_B12","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2337\/diacare.28.10.2384","article-title":"Mortality in Childhood-Onset Type 1 Diabetes","volume":"28","author":"Dahlquist","year":"2005","unstructured":"Dahlquist G, K\u00e4ll\u00e9n B. Mortality in Childhood-Onset Type 1 Diabetes. Diabetes Care. 2005;28(10):1-4.","journal-title":"Diabetes Care"},{"issue":"3","key":"key20220606093152_B13","doi-asserted-by":"crossref","first-page":"121","DOI":"10.4103\/0300-1652.104378","article-title":"Clinical profile and outcomes of adult patients with hyperglycemic emergencies managed at a tertiary care hospital in Nigeria","volume":"53","author":"Edo","year":"2012","unstructured":"Edo AE. Clinical profile and outcomes of adult patients with hyperglycemic emergencies managed at a tertiary care hospital in Nigeria. Niger Med J. 2012;53(3):121-5.","journal-title":"Niger Med J"},{"issue":"4","key":"key20220606093152_B14","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1111\/j.1464-5491.2005.01450.x","article-title":"Clinical characteristics of diabetic ketoacidosis in Korea over the past two decades","volume":"22","author":"Ko","year":"2005","unstructured":"Ko S, Lee W, Lee J, Kwon H, Lee J, Kim S, et al. Clinical characteristics of diabetic ketoacidosis in Korea over the past two decades. Diabet Med. 2005;22(4):466-9.","journal-title":"Diabet Med"},{"issue":"1","key":"key20220606093152_B15","doi-asserted-by":"crossref","first-page":"32","DOI":"10.4103\/2278-0521.151407","article-title":"Electronic health records: Use and barriers among physicians in eastern province of Saudi Arabia","volume":"4","author":"El Mahalli","year":"2015","unstructured":"El Mahalli A. Electronic health records: Use and barriers among physicians in eastern province of Saudi Arabia. Saudi J Heal Sci. 2015;4(1):32.","journal-title":"Saudi J Heal Sci"},{"issue":"1","key":"key20220606093152_B16","doi-asserted-by":"crossref","first-page":"20","DOI":"10.15537\/smj.2015.1.9763","article-title":"Characteristics of pediatric diabetic ketoacidosis patients in Saudi Arabia","volume":"36","author":"Naeem","year":"2015","unstructured":"Naeem MA, Al-Alem HA, Al-Dubayee MS, Al-Juraibah FN, Omair A, Al-Ruwaili AS, et al. Characteristics of pediatric diabetic ketoacidosis patients in Saudi Arabia. Saudi Med J. 2015;36(1):20-5.","journal-title":"Saudi Med J"},{"issue":"1","key":"key20220606093152_B17","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1111\/j.1399-5448.2008.00441.x","article-title":"A 2-yr national population study of pediatric ketoacidosis in Sweden: Predisposing conditions and insulin pump use","volume":"10","author":"Hanas","year":"2009","unstructured":"Hanas R, Lindgren F, Lindblad B. A 2-yr national population study of pediatric ketoacidosis in Sweden: Predisposing conditions and insulin pump use. Pediatr Diabetes. 2009;10(1):33-7.","journal-title":"Pediatr Diabetes"},{"issue":"17","key":"key20220606093152_B18","doi-asserted-by":"crossref","first-page":"1836","DOI":"10.1001\/archinte.166.17.1836","article-title":"Effect of medication nonadherence on hospitalization and mortality among patients with diabetes mellitus","volume":"166","author":"Ho","year":"2006","unstructured":"Ho PM, Rumsfeld JS, Masoudi FA, McClure DL, Plomondon ME, Steiner JF, et al. Effect of medication nonadherence on hospitalization and mortality among patients with diabetes mellitus. Arch Intern Med. 2006;166(17):1836-41.","journal-title":"Arch Intern Med"},{"key":"key20220606093152_B19","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1097\/01.mlr.0000163641.86870.af","article-title":"Impact of medication adherence on hospitalization risk and healthcare cost","author":"Sokol","year":"2005","unstructured":"Sokol MC, McGuigan KA, Verbrugge RR, Epstein RS. Impact of medication adherence on hospitalization risk and healthcare cost. Med Care. 2005;521-30.","journal-title":"Med Care"},{"issue":"4","key":"key20220606093152_B20","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1016\/j.pcl.2015.04.002","article-title":"Preventing Diabetic Ketoacidosis","volume":"62","author":"Jefferies","year":"2015","unstructured":"Jefferies CA, Nakhla M, Derraik JGB, Gunn AJ, Daneman D, Cutfield WS. Preventing Diabetic Ketoacidosis. Pediatr Clin North Am. 2015;62(4):857-71.","journal-title":"Pediatr Clin North Am"},{"issue":"2","key":"key20220606093152_B21","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/S0022-3476(85)80124-4","article-title":"An approach to prevention of recurrent diabetic ketoacidosis in the pediatric population","volume":"107","author":"Golden","year":"1985","unstructured":"Golden MP, Herrold AJ, Orr DP. An approach to prevention of recurrent diabetic ketoacidosis in the pediatric population. J Pediatr. 1985;107(2):195-200.","journal-title":"J Pediatr"},{"issue":"5","key":"key20220606093152_B22","doi-asserted-by":"crossref","first-page":"e193","DOI":"10.3928\/19382359-20170425-01","article-title":"Models of care for adolescents and young adults with type 1 diabetes in transition: Shared medical appointments and telemedicine","volume":"46","author":"Raymond","year":"2017","unstructured":"Raymond JK. Models of care for adolescents and young adults with type 1 diabetes in transition: Shared medical appointments and telemedicine. Pediatr Ann. 2017;46(5):e193-7.","journal-title":"Pediatr Ann"},{"issue":"5","key":"key20220606093152_B23","first-page":"1","article-title":"Precipitating Risk Factors, Clinical Presentation, and Outcome of Diabetic Ketoacidosis in Patients with Type 1 Diabetes","volume":"11","author":"Ahuja","year":"2019","unstructured":"Ahuja W, Kumar N, Kumar S, Rizwan A. Precipitating Risk Factors, Clinical Presentation, and Outcome of Diabetic Ketoacidosis in Patients with Type 1 Diabetes. Cureus. 2019;11(5):1-9.","journal-title":"Cureus"},{"issue":"8","key":"key20220606093152_B24","doi-asserted-by":"crossref","first-page":"729","DOI":"10.2169\/internalmedicine.49.2965","article-title":"Short-Term Case Fatality Rate and Associated Factors among Inpatients with Diabetic Ketoacidosis and Hyperglycemic Hyperosmolar State: A Hospital-Based Analysis over a 15-Year Period","volume":"49","author":"Chen","year":"2010","unstructured":"Chen HF, Wang CY, Lee HY, See TT, Chen MH, Jiang JY, et al. Short-Term Case Fatality Rate and Associated Factors among Inpatients with Diabetic Ketoacidosis and Hyperglycemic Hyperosmolar State: A Hospital-Based Analysis over a 15-Year Period. Intern Med. 2010;49(8):729-37.","journal-title":"Intern Med"},{"issue":"9","key":"key20220606093152_B25","doi-asserted-by":"crossref","first-page":"1142","DOI":"10.1111\/j.1464-5491.2012.03590.x","article-title":"Temporal changes in the diagnosis of type 1 diabetes by diabetic ketoacidosis in Brazil: A nationwide survey","volume":"29","author":"Negrato","year":"2012","unstructured":"Negrato CA, Cobas RA, Gomes MB. Temporal changes in the diagnosis of type 1 diabetes by diabetic ketoacidosis in Brazil: A nationwide survey. Diabet Med. 2012;29(9):1142-7.","journal-title":"Diabet Med"},{"issue":"2","key":"key20220606093152_B26","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1111\/cen.12350","article-title":"Socioeconomic factors associated with pediatric diabetic ketoacidosis admissions in Southern West Virginia","volume":"81","author":"Lewis","year":"2014","unstructured":"Lewis KR, Clark C, Velarde MC. Socioeconomic factors associated with pediatric diabetic ketoacidosis admissions in Southern West Virginia. Clin Endocrinol (Oxf). 2014;81(2):218-21.","journal-title":"Clin Endocrinol (Oxf)"},{"issue":"5","key":"key20220606093152_B27","first-page":"299","article-title":"Diabetic ketoacidosis: clinical characteristics, precipitating factors and outcomes of care","volume":"14","author":"Barski","year":"2012","unstructured":"Barski L, Nevzorov R, Rabaev E, Jotkowitz AB, Harman-Boehm I, Zektser M, et al. Diabetic ketoacidosis: clinical characteristics, precipitating factors and outcomes of care. IMAJ. 2012;14(5):299-303.","journal-title":"IMAJ"},{"issue":"19","key":"key20220606093152_B28","doi-asserted-by":"crossref","first-page":"2511","DOI":"10.1001\/jama.287.19.2511","article-title":"Predictors of acute complications in children with type 1 diabetes","volume":"287","author":"Rewers","year":"2002","unstructured":"Rewers A, Chase HP, Mackenzie T, Walravens P, Roback M, Rewers M, et al. Predictors of acute complications in children with type 1 diabetes. JAMA. 2002;287(19):2511-8.","journal-title":"JAMA"}],"container-title":["Archives of Endocrinology and Metabolism"],"original-title":[],"language":"en","deposited":{"date-parts":[[2022,6,6]],"date-time":"2022-06-06T13:32:21Z","timestamp":1654522341000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.aem-sbem.com\/article\/precipitating-factors-of-diabetic-ketoacidosis-in-type-1-diabetes-patients-at-a-tertiary-hospital-a-cross-sectional-study-with-a-two-time-period-comparison\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6,3]]},"references-count":28,"alternative-id":["10.20945\/2359-3997000000480"],"URL":"https:\/\/doi.org\/10.20945\/2359-3997000000480","relation":{},"ISSN":["2359-3997","2359-4292"],"issn-type":[{"value":"2359-3997","type":"print"},{"value":"2359-4292","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,6,3]]}}}