{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T12:07:20Z","timestamp":1789560440794,"version":"build-2803163510"},"reference-count":0,"publisher":"Archives of Endocrinology and Metabolism","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["A&amp;EM"],"published-print":{"date-parts":[[2026]]},"abstract":"<jats:p>Anaplastic thyroid cancer (ATC) is a highly aggressive histologic subtype of thyroid malignancy. Its rarity, rapidly progressive\nclinical course, along with limitations in health-care resources make management particularly challenging in Latin America.\nIn recent years, substantial advances in the understanding of ATC biology have led to modifications in therapeutic strategies.\nThis consensus aims to raise awareness and provide practical, evidence-based guidance for the diagnosis and management of\nATC, summarizing current diagnostic and therapeutic advances while offering an accessible framework tailored to the Latin\nAmerican context. A multidisciplinary panel of experts in endocrinology, surgery, oncology, pathology, and genetics from Latin\nAmerican countries developed a series of recommendations. Each recommendation is accompanied by its rationale and supporting\nevidence, adapted to the regional context to facilitate implementation. All recommendations were reviewed and voted\non through a non-anonymous process. Recommendation wording was pre-specified and linked to voting thresholds: \u201cshould\u201d\nindicated unanimous agreement (100%); \u201cis recommended\u201d indicated \u226570% agreement; and \u201cmay be considered\u201d was used\nwhen agreement was &lt;70% and\/or when applicability depended on local availability, feasibility, or patient-specific clinical context.\nThe consensus includes 37 recommendations covering the initial approach, diagnosis, and management of locoregional\nand advanced disease. By integrating current evidence with expert consensus and accounting for regional resource variability,\nthis document aims to harmonize clinical practice, support multidisciplinary care, and facilitate timely diagnosis and treatment.\nThese recommendations may also serve as a foundation for future research initiatives and the development and updating of\nregional health policies for this highly lethal disease.<\/jats:p>","DOI":"10.20945\/2359-4292-2026-0100","type":"journal-article","created":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T11:35:21Z","timestamp":1789558521000},"page":"1-21","source":"Crossref","is-referenced-by-count":0,"title":["Latin American Thyroid Society expert panel consensus on anaplastic thyroid cancer"],"prefix":"10.20945","volume":"70","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7450-5832","authenticated-orcid":false,"given":"In\u00e9s","family":"Califano","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5547-599X","authenticated-orcid":false,"given":"Fabiano Mesquita","family":"Callegari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0156-8274","authenticated-orcid":false,"given":"Janete Maria","family":"Cerutti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6759-9463","authenticated-orcid":false,"given":"Aline Lauda Freitas","family":"Chaves","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8765-3044","authenticated-orcid":false,"given":"Gilberto","family":"de Castro Junior","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6157-8055","authenticated-orcid":false,"given":"Jose Miguel Dominguez","family":"Ruiz-Tagle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4487-2444","authenticated-orcid":false,"given":"Agustin","family":"Falco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7058-6321","authenticated-orcid":false,"given":"Ana Am\u00e9lia Oliveira","family":"Hoff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0481-156X","authenticated-orcid":false,"given":"Luiz Paulo","family":"Kowalski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4186-5532","authenticated-orcid":false,"given":"Ana Luiza","family":"Maia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-2791-4195","authenticated-orcid":false,"given":"Marcos David","family":"Pereira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5563-8840","authenticated-orcid":false,"given":"Alvaro","family":"Sanabria","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2742-7085","authenticated-orcid":false,"given":"Fabian","family":"Pitoia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"8510","published-online":{"date-parts":[[2026]]},"container-title":["Archives of Endocrinology and Metabolism"],"original-title":[],"link":[{"URL":"https:\/\/www.aem-sbem.com\/article\/latin-american-thyroid-society-expert-panel-consensus-on-anaplastic-thyroid-cancer\/","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T11:35:22Z","timestamp":1789558522000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.aem-sbem.com\/article\/latin-american-thyroid-society-expert-panel-consensus-on-anaplastic-thyroid-cancer\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":0,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2026]]},"published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.20945\/2359-4292-2026-0100","relation":{},"ISSN":["2359-3997"],"issn-type":[{"value":"2359-3997","type":"print"}],"subject":[],"published":{"date-parts":[[2026]]}}}