{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,30]],"date-time":"2022-03-30T01:34:23Z","timestamp":1648604063700},"reference-count":0,"publisher":"ARAN Ediciones","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutr Hosp"],"abstract":"<jats:p>Introducci\u00f3n: la alteraci\u00f3n histol\u00f3gica en el intestino delgado de los enfermos celiacos produce una pobre absorci\u00f3n que deteriora o dificulta una ganancia \u00f3ptima de peso. Esto puede ser el resultado de un aumento de la expresi\u00f3n de las interleuquinas Th17 gluten-espec\u00edficas.Objetivo: el objetivo de este estudio fue comparar la expresi\u00f3n de las interleuquinas Th17 en pacientes celiacos con peso normal y sobrepeso\/ obesidad. M\u00e9todos: se estudiaron 22 pacientes con reciente diagn\u00f3stico de enfermedad celiaca: 15 con peso normal y siete con sobrepeso\/obesidad. Se tomaron biopsias de intestino delgado para la evaluaci\u00f3n de la expresi\u00f3n de las interleuquinas a trav\u00e9s de PCR a tiempo-real.Resultados: los niveles de expresi\u00f3n de las interleuquinas Th17 mostraron una tendencia a ser m\u00e1s altos en las biopsias de intestino de pacientes con sobrepeso\/obesidad en comparaci\u00f3n a los celiacos con peso normal, sin embargo, esta diferencia no fue significativa.Conclusi\u00f3n: el exceso de peso en pacientes celiacos no es influenciado por los niveles de expresi\u00f3n de interleuquinas Th17.<\/jats:p>","DOI":"10.20960\/nh.1554","type":"journal-article","created":{"date-parts":[[2018,9,7]],"date-time":"2018-09-07T04:56:27Z","timestamp":1536296187000},"page":"957","source":"Crossref","is-referenced-by-count":1,"title":["Sobrepeso y obesidad en enfermedad celiaca: expresi\u00f3n del perfil de interleuquinas Th17"],"prefix":"10.20960","volume":"35","author":[{"given":"Alejandra","family":"Parada","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carolina","family":"Aguirre","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco","family":"P\u00e9rez-Bravo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"8588","published-online":{"date-parts":[[2018,8,2]]},"container-title":["Nutrici\u00f3n Hospitalaria"],"original-title":[],"link":[{"URL":"http:\/\/revista.nutricionhospitalaria.net\/index.php\/nh\/article\/viewFile\/1554\/985","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/revista.nutricionhospitalaria.net\/index.php\/nh\/article\/viewFile\/1554\/985","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,9,7]],"date-time":"2018-09-07T04:56:27Z","timestamp":1536296187000},"score":1,"resource":{"primary":{"URL":"http:\/\/revista.nutricionhospitalaria.net\/index.php\/nh\/article\/view\/1554"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8,2]]},"references-count":0,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2018,8,2]]}},"URL":"https:\/\/doi.org\/10.20960\/nh.1554","relation":{},"ISSN":["1699-5198","0212-1611"],"issn-type":[{"value":"1699-5198","type":"electronic"},{"value":"0212-1611","type":"print"}],"subject":[],"published":{"date-parts":[[2018,8,2]]}}}