{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T13:25:17Z","timestamp":1762521917826},"reference-count":0,"publisher":"ARAN Ediciones","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutr Hosp"],"abstract":"<jats:p>Introducci\u00f3n y objetivos: el cobre (Cu) es un oligoelemento muy estudiado, pero poco se sabe de su evoluci\u00f3n en los pacientes alimentados por gastrostom\u00eda endosc\u00f3pica (GEP). Pretendemos evaluar la evoluci\u00f3n del Cu s\u00e9rico desde la gastrostom\u00eda hasta 12 semanas despu\u00e9s de la intervenci\u00f3n en estos pacientes alimentados con preparaciones dom\u00e9sticas. \u00a0M\u00e9todos: realizamos un estudio observacional prospectivo para evaluar el Cu s\u00e9rico, la alb\u00famina, la transferrina y el \u00edndice de masa corporal (IMC) en el momento de la GEP, tras 4 semanas y 12 semanas despu\u00e9s de la intervenci\u00f3n. Los datos incluyen edad, g\u00e9nero, NRS 2002 y enfermedad subyacente: c\u00e1nceres de cabeza y cuello (CCC) y disfagia neurol\u00f3gica (DN). Despu\u00e9s de la intervenci\u00f3n, estos pacientes fueron alimentados conpreparaciones dom\u00e9sticas.\u00a0Resultados: 146 enfermos (89 hombres), entre 21\u201095 a\u00f1os: CCC-56, DN-90. Valores de Cu entre 42-160 \u03bcg\/dl (normal: 70-140 \u03bcg\/dl); normales 89% (n = 130); bajos 11% (n = 16), alb\u00famina baja: 53% (n = 77), transferrina baja: 65% (n = 94), IMC bajo: 53% (n = 78). Despu\u00e9s de 4 semanas: valores normales de Cu en 93% y bajos en 7%, alb\u00famina baja en 34%, transferrina baja en 52%. Tras 12 semanas: valores normales de Cu en 95% y bajos en 5%, alb\u00famina baja en 25%, transferrina baja en 32%. No encontramos diferencias significativas en el Cus\u00e9rico cuando se compara edad, g\u00e9nero, enfermedad subyacente, IMC, alb\u00famina y transferrina.\u00a0Conclusiones: la mayor\u00eda de los enfermos presentan Cu s\u00e9rico normal en el momento de la gastrostom\u00eda. Para los enfermos con Cu s\u00e9rico bajo antes del procedimiento, la alimentaci\u00f3n con preparaciones dom\u00e9sticas parece suficiente para su normalizaci\u00f3n progresiva.<\/jats:p>","DOI":"10.20960\/nh.91","type":"journal-article","created":{"date-parts":[[2016,6,6]],"date-time":"2016-06-06T17:45:02Z","timestamp":1465235102000},"source":"Crossref","is-referenced-by-count":3,"title":["Evoluci\u00f3n del cobre s\u00e9rico en pacientes sometidos a gastrostom\u00eda endosc\u00f3pica para nutrici\u00f3n enteral a largo plazo"],"prefix":"10.20960","volume":"33","author":[{"given":"Carla Adriana","family":"Santos","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jorge","family":"Fonseca","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisabete","family":"Carolino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Teresa","family":"Lopes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ant\u00f3nio","family":"Sousa Guerreiro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"8588","published-online":{"date-parts":[[2016,3,25]]},"container-title":["Nutrici\u00f3n Hospitalaria"],"original-title":[],"link":[{"URL":"http:\/\/revista.nutricionhospitalaria.net\/index.php\/nh\/article\/viewFile\/91\/48","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/revista.nutricionhospitalaria.net\/index.php\/nh\/article\/viewFile\/91\/48","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2016,6,6]],"date-time":"2016-06-06T17:45:02Z","timestamp":1465235102000},"score":1,"resource":{"primary":{"URL":"http:\/\/revista.nutricionhospitalaria.net\/index.php\/nh\/article\/view\/91"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,3,25]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2016,3,25]]}},"URL":"https:\/\/doi.org\/10.20960\/nh.91","relation":{},"ISSN":["1699-5198","0212-1611"],"issn-type":[{"value":"1699-5198","type":"electronic"},{"value":"0212-1611","type":"print"}],"subject":[],"published":{"date-parts":[[2016,3,25]]}}}