{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T15:26:53Z","timestamp":1787498813641,"version":"build-2736575974"},"reference-count":0,"publisher":"African Traditional Herbal Medicine Supporters Initiative (ATHMSI)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Afr J  Tradit Complement Altern Med"],"abstract":"<jats:p>Background: Chinese medicine theory shows that \u201clung being connected with large intestine\u201d, and the modern western\r\nmedicine also shows that the lung and intestinal tract affect each other in physiological and pathological conditions. If\r\nthe lung ventilation dysfunction is caused by inflammatory exudate or secretions obstruction of the small airway\r\nventilation, blood gas partial pressure is increased and intestinal gas absorption difficulty may lead to intestinal\r\ninflation and dysfunction (Wang N et al., 2011). Rheum palmatum L. can play the roles of anti-coagulation and\r\nanti-thrombosis, and improve microcirculation through lowering the endotoxin-induced permeability of microvascular\r\ntissue, reducing tissue oedema, decreasing inflammatory exudation and necrosis, and enhancing cyto-protection\r\nmechanism (Yang TZ et al., 2014). Therefore, systemic evaluation of the evidence pertaining to the usage of Rheum\r\npalmatum L. in treating acute lung injury and acute respiratory distress syndrome (ARDS) has significant\r\nclinical significance.\r\nMaterials and Methods: Various Electronic Databases CBM, CNKI, VIP, Wanfang, PubMed and Cochrane Library\r\nwere searched until December 2015. Numerous randomized-controlled trials (RCTs) evaluating the efficacy of\r\nRheum palmatum L. for the treatment of acute lung injury and acute respiratory distress syndrome were\r\ncollected. The quality of the included studies was evaluated and a meta-analysis was performed using the RevMan5.0\r\nsoftware.\r\nResults: Eight RCTs involving 489 patients were selected for this review. The results of the Meta-analysis revealed that\r\nRheum palmatum L. therapy, combined with routine comprehensive treatment, was significantly superior to that of\r\nroutine comprehensive treatment alone, in the areas of decreasing mortality, the mechanical ventilation time, the level\r\nof interleukin-6,8 and the untoward effect, and also in improving arterial blood gas (PaO2\/FiO2, PaO2) (P<\/jats:p>","DOI":"10.21010\/ajtcam.v14i2.35","type":"journal-article","created":{"date-parts":[[2017,3,29]],"date-time":"2017-03-29T06:59:47Z","timestamp":1490770787000},"page":"334-347","source":"Crossref","is-referenced-by-count":8,"title":["THE USE OF RHEUM PALMATUM L. IN THE TREATMENT OF ACUTE RESPIRATORY DISTRESS SYNDROME: A META-ANALYSIS OF RANDOMIZED, CONTROLLED TRIALS"],"prefix":"10.21010","volume":"14","author":[{"given":"Tie-zhu","family":"Yang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yue-Yun","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiu-Fang","family":"Ding","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia-Xu","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei-Jing","family":"Kou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-Juan","family":"Zou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"8656","published-online":{"date-parts":[[2017,1,13]]},"container-title":["African Journal of Traditional, Complementary and Alternative Medicines"],"original-title":[],"link":[{"URL":"http:\/\/journals.athmsi.org\/index.php\/ajtcam\/article\/download\/4603\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/journals.athmsi.org\/index.php\/ajtcam\/article\/download\/4603\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,8]],"date-time":"2023-05-08T04:43:25Z","timestamp":1683521005000},"score":1,"resource":{"primary":{"URL":"http:\/\/journals.athmsi.org\/index.php\/ajtcam\/article\/view\/4603"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1,13]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2017,1,13]]}},"URL":"https:\/\/doi.org\/10.21010\/ajtcam.v14i2.35","relation":{},"ISSN":["2505-0044","0189-6016"],"issn-type":[{"value":"2505-0044","type":"electronic"},{"value":"0189-6016","type":"print"}],"subject":[],"published":{"date-parts":[[2017,1,13]]}}}