{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,5,6]],"date-time":"2023-05-06T09:40:15Z","timestamp":1683366015685},"reference-count":0,"publisher":"African Traditional Herbal Medicine Supporters Initiative (ATHMSI)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Afr J  Tradit Complement Altern Med"],"abstract":"<jats:p>Background: Currently-available antidepressant agents produce various adverse effects, and are expensive. At present,&#x0D;\nvarious plants are being evaluated for their possible role against numerous diseases, and no doubt, the role of traditional&#x0D;\nand complementary medicines in the development of effective therapy is incredible. The present study was designed to&#x0D;\nevaluate antidepressant-like activity of Raphanus sativus L. Var. caudatus at different doses in mice.&#x0D;\nMaterials and Methods: Antidepressant potential of ethanolic extract of Raphanus caudatus L. was evaluated at three&#x0D;\ndifferent doses 250 mg\/kg, 500 mg\/kg and 1000 mg\/kg by using forced swim test and tail suspension test on albino&#x0D;\nmale mice. The results were compared with control and standard mice groups administered with normal saline and&#x0D;\nFluoxetine respectively. In both parameters immobility period was recorded two times during 60 days dosing.&#x0D;\nResults: The ethanol extract at all three tested doses (250 mg\/kg, 500 mg\/kg and 1000 mg \/kg) and standard fluoxetine&#x0D;\ndemonstrated notable antidepressant-like activity (p<\/jats:p>","DOI":"10.21010\/ajtcam.v14i3.15","type":"journal-article","created":{"date-parts":[[2017,3,29]],"date-time":"2017-03-29T13:00:04Z","timestamp":1490792404000},"page":"142-146","source":"Crossref","is-referenced-by-count":2,"title":["BEHAVIORAL EVIDENCE OF ANTIDEPRESSANT-LIKE ACTIVITY OF RAPHANUS SATIVUS L. VAR. CAUDATUS IN MICE"],"prefix":"10.21010","volume":"14","author":[{"given":"Ishrat","family":"Younus","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Afshan","family":"Siddiq","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"8656","published-online":{"date-parts":[[2017,3,1]]},"container-title":["African Journal of Traditional, Complementary and Alternative Medicines"],"original-title":[],"link":[{"URL":"http:\/\/journals.athmsi.org\/index.php\/ajtcam\/article\/download\/4666\/2895","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/journals.athmsi.org\/index.php\/ajtcam\/article\/download\/4666\/2895","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,6]],"date-time":"2023-05-06T09:08:10Z","timestamp":1683364090000},"score":1,"resource":{"primary":{"URL":"http:\/\/journals.athmsi.org\/index.php\/ajtcam\/article\/view\/4666"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,3,1]]},"references-count":0,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2017,3,1]]}},"URL":"https:\/\/doi.org\/10.21010\/ajtcam.v14i3.15","relation":{},"ISSN":["2505-0044","0189-6016"],"issn-type":[{"value":"2505-0044","type":"electronic"},{"value":"0189-6016","type":"print"}],"subject":[],"published":{"date-parts":[[2017,3,1]]}}}